Q94AA9
PR
Gene name |
XGD1 (At5g33290, F19N2.10) |
Protein name |
Xylogalacturonan beta-1,3-xylosyltransferase |
Names |
Protein XYLOGALACTURONAN DEFICIENT 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G33290 |
EC number |
2.4.2.41: Pentosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q94AA9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q94AA9-F1 | Predicted | AlphaFoldDB |
18 variants for Q94AA9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH03215577 | 15 | T>A | No | 1000Genomes | |
| ENSVATH00668479 | 48 | I>T | No | 1000Genomes | |
| ENSVATH11718061 | 72 | L>F | No | 1000Genomes | |
| ENSVATH07167048 | 90 | S>F | No | 1000Genomes | |
| ENSVATH11718062 | 110 | K>N | No | 1000Genomes | |
| tmp_5_12558769_A_C | 111 | I>L | No | 1000Genomes | |
| tmp_5_12558960_T_G | 125 | D>E | No | 1000Genomes | |
| tmp_5_12558965_C_T | 127 | A>V | No | 1000Genomes | |
| ENSVATH14479749 | 138 | S>F | No | 1000Genomes | |
| ENSVATH11718120 | 255 | D>Y | No | 1000Genomes | |
| ENSVATH11718121 | 257 | V>I | No | 1000Genomes | |
| tmp_5_12561325_T_C | 330 | F>L | No | 1000Genomes | |
| ENSVATH00668486 | 340 | I>V | No | 1000Genomes | |
| ENSVATH11718198 | 351 | E>K | No | 1000Genomes | |
| ENSVATH00668488 | 365 | N>D | No | 1000Genomes | |
| tmp_5_12561482_C_T | 382 | T>I | No | 1000Genomes | |
| tmp_5_12561550_G_T | 405 | A>S | No | 1000Genomes | |
| tmp_5_12561722_G_A | 462 | R>K | No | 1000Genomes |
No associated diseases with Q94AA9
1 regional properties for Q94AA9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exostosin, GT47 domain | 162 - 451 | IPR040911 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.2.41 | Pentosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| trans-Golgi network | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| UDP-xylosyltransferase activity | Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule. |
| xylogalacturonan beta-1,3-xylosyltransferase activity | Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| pectin biosynthetic process | The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. |
| protein glycosylation | A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. |
| xylogalacturonan metabolic process | The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues. |
14 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A5D7I4 | EXT1 | Exostosin-1 | Bos taurus (Bovine) | PR |
| O77783 | EXT2 | Exostosin-2 | Bos taurus (Bovine) | PR |
| Q9Y169 | sotv | Exostosin-2 | Drosophila melanogaster (Fruit fly) | PR |
| Q16394 | EXT1 | Exostosin-1 | Homo sapiens (Human) | PR |
| O43909 | EXTL3 | Exostosin-like 3 | Homo sapiens (Human) | PR |
| P97464 | Ext1 | Exostosin-1 | Mus musculus (Mouse) | PR |
| P70428 | Ext2 | Exostosin-2 | Mus musculus (Mouse) | PR |
| Q9WVL6 | Extl3 | Exostosin-like 3 | Mus musculus (Mouse) | PR |
| Q10SX7 | Os03g0107900 | Probable glucuronosyltransferase Os03g0107900 | Oryza sativa subsp japonica (Rice) | PR |
| O01704 | rib-1 | Exostosin-1 homolog | Caenorhabditis elegans | PR |
| Q9LFP3 | At5g11130/At5g11120 | Probable glycosyltransferase At5g11130 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3EAR7 | At3g42180 | Probable glycosyltransferase At3g42180 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5IGR8 | ext1a | Exostosin-1a | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q5IGR7 | ext1b | Exostosin-1b | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAPRSRRCS | LSLLTLFSIT | LILISVSLFV | STKPANKPFL | DYRNQFSISI | SISSPLEQNT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TNTSFVSASP | PLSPLGQSNT | TNTILASSSS | SSSFSDHQNQ | NKSPSPTSKK | IVIRKRSGLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KIESDLAKAR | AAIKKAASTQ | NYVSSLYKNP | AAFHQSHTEM | MNRFKVWTYT | EGEVPLFHDG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PVNDIYGIEG | QFMDEMCVDG | PKSRSRFRAD | RPENAHVFFI | PFSVAKVIHF | VYKPITSVEG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FSRARLHRLI | EDYVDVVATK | HPYWNRSQGG | DHFMVSCHDW | APDVIDGNPK | LFEKFIRGLC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NANTSEGFRP | NVDVSIPEIY | LPKGKLGPSF | LGKSPRVRSI | LAFFAGRSHG | EIRKILFQHW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KEMDNEVQVY | DRLPPGKDYT | KTMGMSKFCL | CPSGWEVASP | REVEAIYAGC | VPVIISDNYS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LPFSDVLNWD | SFSIQIPVSR | IKEIKTILQS | VSLVRYLKMY | KRVLEVKQHF | VLNRPAKPYD |
| 490 | |||||
| VMHMMLHSIW | LRRLNLRLGT |