Q9H239
PR
Gene name |
MMP28 (MMP25, UNQ1893/PRO4339) |
Protein name |
Matrix metalloproteinase-28 |
Names |
MMP-28, Epilysin |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:79148 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9H239
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9H239-F1 | Predicted | AlphaFoldDB |
568 variants for Q9H239
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| TCGA novel | 1 | M>? | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290098914 rs554782960 |
2 | V>A | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA290098905 rs987667402 |
4 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs901164018 CA290098904 |
5 | V>A | No |
TOPMed ClinGen |
|
|
CA399154071 rs1238042590 |
5 | V>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1238042590 CA399154073 |
5 | V>I | No |
TOPMed gnomAD ClinGen |
|
|
rs1039749469 CA290098902 |
6 | G>A | No |
TOPMed gnomAD ClinGen |
|
|
CA399154063 rs1187768478 |
7 | L>I | No |
TOPMed ClinGen |
|
|
rs1350184108 CA399154053 |
8 | L>R | No |
gnomAD ClinGen |
|
|
rs1448764315 CA399154045 |
10 | R>C | No |
gnomAD ClinGen |
|
|
rs1292593615 CA399154036 |
11 | A>V | No |
TOPMed gnomAD ClinGen |
|
|
rs750549071 CA290098861 |
13 | Q>H | No |
ExAC gnomAD ClinGen |
|
|
CA290098866 rs754833581 |
13 | Q>P | No |
ExAC gnomAD ClinGen |
|
|
rs1438516193 CA399154002 |
17 | W>C | No |
ClinGen gnomAD |
|
|
rs757238191 CA399153972 |
22 | A>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290098834 rs757238191 |
22 | A>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs930147227 CA290098830 |
22 | A>V | No |
TOPMed ClinGen |
|
|
rs1265628259 CA399153952 |
25 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1265628259 CA399153950 |
25 | A>V | No |
TOPMed gnomAD ClinGen |
|
|
CA399153946 rs1392385365 |
26 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1338892568 CA399153939 |
27 | R>C | No |
TOPMed ClinGen |
|
|
CA399153933 rs1488963679 |
28 | G>E | No |
gnomAD ClinGen |
|
|
rs201598708 TCGA novel CA290098821 |
28 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
1000Genomes ESP ExAC TOPMed gnomAD NCI-TCGA ClinGen |
|
rs1267436021 CA399153928 |
29 | G>S | No |
gnomAD ClinGen |
|
|
CA399153922 rs1214597769 |
30 | Q>* | No |
ClinGen gnomAD |
|
|
CA399153918 rs1568216457 |
30 | Q>H | No |
ClinGen Ensembl |
|
|
CA399153910 rs963801814 CA290098809 |
31 | E>D | No |
TOPMed gnomAD ClinGen |
|
|
rs764144708 CA290098791 |
33 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs1016320009 CA290098794 |
33 | R>S | No |
ClinGen Ensembl |
|
|
CA290098789 rs763434043 |
35 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1432275758 CA399153878 |
37 | E>Q | No |
TOPMed gnomAD ClinGen |
|
|
rs1555608692 CA399151986 |
38 | A>T | No |
gnomAD ClinGen |
|
|
CA290089486 rs200955662 |
38 | A>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1555608682 CA399151968 |
41 | E>* | No |
gnomAD ClinGen |
|
|
CA399151963 rs1555608681 |
41 | E>D | No |
gnomAD ClinGen |
|
|
rs1555608682 CA399151970 |
41 | E>K | No |
ClinGen gnomAD |
|
|
CA399151969 rs1555608682 |
41 | E>Q | No |
gnomAD ClinGen |
|
|
CA290089466 rs181150846 |
44 | G>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA290089468 rs181150846 |
44 | G>R | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290089461 rs552076033 |
44 | G>V | No |
ClinGen 1000Genomes |
|
|
CA399151936 rs1555608660 |
45 | Y>* | No |
ClinGen gnomAD |
|
|
CA399151933 rs1555608656 |
46 | L>F | No |
gnomAD ClinGen |
|
|
CA290089452 rs772754493 |
48 | E>D | No |
ExAC gnomAD ClinGen |
|
|
CA399151921 rs1223843467 |
48 | E>K | No |
ClinGen TOPMed |
|
|
CA290089451 rs771642501 |
49 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290089445 rs761444557 |
50 | V>D | No |
ExAC gnomAD ClinGen |
|
|
CA399151907 rs1009727691 |
50 | V>I | No |
ClinGen gnomAD |
|
|
CA290089449 rs1009727691 |
50 | V>L | No |
ClinGen gnomAD |
|
|
CA399151898 rs1342355706 |
51 | P>L | No |
ClinGen TOPMed |
|
|
CA399151896 rs1555608627 |
52 | K>E | No |
gnomAD ClinGen |
|
|
CA290089444 rs201680056 |
52 | K>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA399151890 rs1555608621 |
53 | A>T | No |
ClinGen gnomAD |
|
|
CA399151883 rs1555608618 |
54 | P>S | No |
gnomAD ClinGen |
|
|
CA399151877 rs1555608615 |
55 | T>A | No |
gnomAD ClinGen |
|
|
CA290089443 rs768696597 |
57 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs749225885 CA290089440 |
58 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
|
rs779882824 CA399151860 |
58 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779882824 CA290089436 |
58 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1263041837 CA399151858 |
59 | F>L | No |
TOPMed ClinGen |
|
|
rs769487242 CA290089417 |
60 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777998075 CA290089407 |
61 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs1555608574 CA399151832 |
62 | A>G | No |
ClinGen gnomAD |
|
|
CA399151831 rs1555608574 |
62 | A>V | No |
ClinGen gnomAD |
|
| TCGA novel | 64 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs201925301 CA290089281 |
65 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs560975119 CA290089280 |
65 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs763590338 CA290089273 |
67 | Q>R | No |
ExAC gnomAD ClinGen |
|
|
CA290089269 rs775445556 CA290089264 |
69 | V>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1378575627 CA399151772 |
70 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
CA399151771 rs1555608458 |
70 | S>Y | No |
ClinGen gnomAD |
|
|
rs1568173984 CA399151755 |
73 | P>T | No |
Ensembl ClinGen |
|
| TCGA novel | 75 | S>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399151736 rs765062835 |
75 | S>R | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs759557284 CA290089255 |
76 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770768624 CA290089249 |
77 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs968106578 CA399151718 |
79 | D>H | No |
Ensembl ClinGen |
|
|
rs968106578 CA290089234 |
79 | D>N | No |
Ensembl ClinGen |
|
| TCGA novel | 79 | D>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs373463098 CA290089206 |
80 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ESP ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
CA290089202 rs531148530 |
80 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs373463098 CA399151711 |
80 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs749353494 CA290089199 |
81 | A>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 82 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290089198 rs780233358 |
83 | L>P | No |
ExAC gnomAD ClinGen |
|
|
CA290089194 rs375923654 |
84 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs200590299 CA290089191 |
84 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766859009 CA290089190 |
88 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757698905 CA290089189 |
88 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1568173515 CA399151657 |
89 | P>L | No |
Ensembl ClinGen |
|
|
CA290089185 rs751213333 |
89 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA290089183 rs545716418 |
90 | R>C | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
rs901981147 CA290089166 |
90 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA399151653 rs901981147 |
90 | R>L | No |
TOPMed gnomAD ClinGen |
|
|
rs199792911 CA290089154 |
92 | G>R | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 92 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs973259197 CA290089149 |
93 | V>I | No |
ClinGen TOPMed |
|
|
CA290089124 rs759455709 |
94 | T>R | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 95 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290089120 rs776564710 |
96 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766097476 CA290089119 |
96 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs776564710 CA399151621 |
96 | T>P | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290089116 rs889362604 |
97 | N>D | No |
Ensembl ClinGen |
|
|
CA399151611 rs1555608382 |
97 | N>K | No |
gnomAD ClinGen |
|
|
CA399151606 rs1555608373 |
98 | S>I | No |
gnomAD ClinGen |
|
|
rs760494318 CA290089112 |
98 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA290089107 rs750488670 |
100 | A>E | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 100 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290089102 rs750488670 |
100 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 102 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399151584 rs1555608371 |
102 | W>R | No |
gnomAD ClinGen |
|
|
rs573447178 CA290089094 |
104 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA399151569 rs1555608369 |
104 | E>K | No |
ClinGen gnomAD |
|
|
rs1568173027 CA399151565 |
104 | E>V | No |
Ensembl ClinGen |
|
|
rs775429933 CA399151563 |
105 | R>G | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs775429933 CA290089090 |
105 | R>W | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399151546 rs1555608352 |
107 | S>N | No |
gnomAD ClinGen |
|
|
CA290089088 rs908525502 |
109 | L>S | No |
TOPMed gnomAD ClinGen |
|
|
rs1049352294 CA290089086 |
111 | A>D | No |
ClinGen Ensembl |
|
| TCGA novel | 111 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399151514 rs1340326070 |
112 | R>G | No |
TOPMed gnomAD ClinGen |
|
|
rs1219856597 CA399151505 |
113 | H>Y | No |
ClinGen TOPMed |
|
| TCGA novel | 114 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290089058 rs562955735 |
114 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs746307365 CA290089062 |
114 | R>W | Variant assessed as Somatic; 9.282e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs375453890 CA290089056 |
115 | T>A | No |
ESP TOPMed gnomAD ClinGen |
|
|
rs747351869 CA290089051 |
115 | T>I | No |
ExAC gnomAD ClinGen |
|
|
CA290089050 rs747351869 |
115 | T>N | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 116 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290089049 rs778238911 |
117 | M>R | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs778238911 CA399151481 |
117 | M>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs762050128 CA290089045 |
118 | R>G | No |
ClinGen Ensembl |
|
|
CA290089042 rs757981837 |
119 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs368472692 CA290089041 |
119 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 119 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 120 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290089040 rs764592511 |
122 | R>C | No |
ExAC gnomAD ClinGen |
|
|
rs1555608283 CA399151440 |
122 | R>H | No |
ClinGen gnomAD |
|
|
rs542660936 CA290089036 |
126 | Q>* | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 127 | G>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1204893122 CA399150809 |
128 | N>D | No |
ClinGen TOPMed |
|
|
rs750434930 CA290085176 |
128 | N>K | No |
ClinGen ExAC gnomAD |
|
|
CA290085178 rs756045524 |
128 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA290085168 rs201780117 |
129 | K>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 129 | K>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399150786 rs1555606647 |
130 | W>C | No |
ClinGen gnomAD |
|
|
rs752810494 CA290085144 |
130 | W>R | No |
ExAC gnomAD ClinGen |
|
|
rs919211337 CA290085140 |
135 | L>I | No |
Ensembl ClinGen |
|
|
CA290085139 rs973134377 |
135 | L>P | No |
ClinGen Ensembl |
|
|
CA290085138 rs560605503 |
136 | S>Y | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs759874056 CA290085133 |
138 | R>C | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399150701 rs1013683814 |
138 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA290085117 rs1013683814 |
138 | R>L | No |
TOPMed gnomAD ClinGen |
|
|
rs759874056 CA399150703 |
138 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1033851665 CA290085110 |
142 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1555606620 CA399150662 |
142 | W>G | No |
ClinGen gnomAD |
|
|
CA290085093 rs771193067 |
144 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399150639 CA290085084 rs532099250 |
144 | E>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs773773026 CA290085081 |
145 | H>R | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290085075 rs201410342 |
147 | P>A | No |
ClinGen ExAC |
|
|
CA290085063 rs879018115 |
147 | P>L | No |
ClinGen TOPMed |
|
|
CA399150605 rs1555606552 |
148 | E>G | No |
gnomAD ClinGen |
|
|
rs1555606553 CA399150610 |
148 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA290085037 rs560787866 |
149 | P>L | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290085036 rs560787866 |
149 | P>Q | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290085039 rs779299235 |
149 | P>S | No |
ClinGen ExAC |
|
|
CA399150577 rs1314636123 |
151 | V>F | No |
TOPMed ClinGen |
|
|
rs755638138 CA399150570 |
152 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs540834874 CA290084983 |
152 | R>P | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
rs540834874 CA290084992 |
152 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs755638138 CA290085005 |
152 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs115343634 CA290084982 |
153 | G>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA290084964 rs751333303 |
154 | A>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs754124166 CA290084952 |
155 | V>M | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290084948 rs766498522 |
156 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290084951 rs766498522 |
156 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290084942 rs760841295 |
156 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
|
CA399150535 rs766498522 |
156 | R>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290084925 rs768046033 |
157 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs575740651 CA290084900 |
158 | A>T | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1410002860 CA399150510 |
158 | A>V | No |
ClinGen TOPMed |
|
|
rs1299556556 CA399150488 |
160 | Q>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs376773362 CA290084896 |
162 | W>* | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs376773362 CA290084894 |
162 | W>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 162 | W>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399150452 rs1555606458 |
163 | S>R | No |
gnomAD ClinGen |
|
|
rs1390323440 CA399150460 |
163 | S>R | No |
TOPMed ClinGen |
|
|
CA399150440 rs1555606445 |
165 | V>D | No |
ClinGen gnomAD |
|
|
CA399150443 rs1555606447 |
165 | V>I | No |
ClinGen gnomAD |
|
|
CA399150429 rs1244196176 |
167 | A>S | No |
TOPMed gnomAD ClinGen |
|
|
CA290084885 rs769133820 |
167 | A>V | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290084873 rs373261169 |
168 | L>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA290084857 rs377300676 |
169 | E>D | No |
ClinGen Ensembl |
|
| TCGA novel | 170 | F>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290084850 rs573260163 |
171 | W>L | No |
1000Genomes ExAC gnomAD ClinGen |
|
|
CA290084846 rs961646838 |
173 | A>V | No |
gnomAD ClinGen |
|
|
CA290084830 rs777653586 |
175 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399150377 rs777653586 |
175 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290084824 rs758271265 |
177 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA290084791 rs372443837 |
179 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA399150340 rs1598434341 |
181 | I>M | No |
ClinGen Ensembl |
|
|
CA399150342 rs767563445 |
181 | I>N | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290084774 rs767563445 |
181 | I>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290084761 rs368769155 |
182 | R>Q | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs762370811 CA290084770 |
182 | R>W | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290084749 rs375265707 |
183 | L>F | No |
ESP ExAC gnomAD ClinGen |
|
|
rs1172011145 CA399150326 |
184 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1555606372 CA399150314 |
186 | F>C | No |
ClinGen gnomAD |
|
| TCGA novel | 186 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1555606370 CA399150303 |
187 | Q>H | No |
ClinGen gnomAD |
|
|
rs775878320 CA290084743 |
189 | D>E | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 189 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399150282 rs1352456425 |
190 | H>Q | No |
TOPMed ClinGen |
|
|
CA290084739 rs372323971 |
191 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs776189829 CA290084736 |
192 | D>N | No |
ExAC gnomAD ClinGen |
|
|
rs1385585901 CA399150266 |
193 | G>R | No |
TOPMed gnomAD ClinGen |
|
| TCGA novel | 193 | G>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs759605469 CA290084729 |
198 | F>S | No |
gnomAD ClinGen |
|
| TCGA novel | 200 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290084727 rs746875822 |
200 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399150209 rs746875822 |
200 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 201 | P>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399150189 CA290084720 rs777884367 |
202 | G>R | No |
ExAC gnomAD ClinGen |
|
|
CA290082478 rs753052718 |
203 | G>D | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1013029066 CA290082468 |
204 | A>V | No |
ClinGen TOPMed |
|
| TCGA novel | 206 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399149744 rs765574799 |
207 | H>Q | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 207 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399149742 rs1555605139 |
208 | A>T | No |
gnomAD ClinGen |
|
| TCGA novel | 208 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs529273884 CA290082436 |
209 | F>S | No |
1000Genomes ClinGen |
|
|
CA290082430 rs1033215349 |
211 | P>S | No |
ClinGen TOPMed |
|
|
CA290082421 rs776151150 |
212 | R>C | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399149718 rs776151150 |
212 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290082414 rs1000026322 |
212 | R>H | No |
TOPMed gnomAD ClinGen |
|
|
CA399149716 rs1000026322 |
212 | R>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs776151150 CA399149719 |
212 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770434341 CA290082412 |
213 | R>G | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399149713 rs760282921 |
213 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290082411 rs760282921 |
213 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399149715 rs770434341 |
213 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399149711 rs563321974 |
214 | G>C | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290082384 rs563321974 |
214 | G>R | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290082398 rs563321974 |
214 | G>S | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA399149705 rs1326416466 |
215 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA399149694 rs1555605098 |
216 | A>V | No |
gnomAD ClinGen |
|
|
rs778757734 CA290082374 |
218 | F>C | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs973973035 CA399149679 |
218 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA399149673 rs1555605066 |
219 | D>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA290082349 rs550042644 |
219 | D>G | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
rs1555605078 CA399149676 |
219 | D>N | No |
gnomAD ClinGen |
|
|
rs746039705 CA290082342 |
220 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
CA290082332 rs781304682 |
220 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751603102 CA290082317 |
221 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA399149665 rs757516159 |
221 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs757516159 CA290082319 |
221 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA290082311 rs372881071 |
223 | R>H | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs372881071 CA290082310 |
223 | R>L | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs372881071 CA399149649 |
223 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA290082315 rs777893799 |
223 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA290082288 rs765569858 |
225 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs943402562 CA290082278 |
227 | S>C | No |
TOPMed ClinGen |
|
|
CA290082273 rs759849789 |
227 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs368717030 CA290082249 |
228 | R>H | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 229 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399149615 rs1187097680 |
229 | R>H | No |
ClinGen TOPMed |
|
|
rs533461832 CA290082242 |
230 | R>H | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 230 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771767357 CA290082212 |
231 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290082228 TCGA novel rs772845386 |
231 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC TOPMed gnomAD NCI-TCGA |
|
rs761787539 CA290082204 |
232 | R>C | No |
ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 232 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs370806648 CA290082198 |
232 | R>L | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
CA399149603 rs761787539 |
232 | R>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399149593 rs1555605014 |
233 | N>K | No |
gnomAD ClinGen |
|
|
rs377269394 CA290082183 |
234 | L>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs377269394 CA290082193 |
234 | L>Q | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs1555604998 CA399149582 |
235 | F>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
gnomAD ClinGen NCI-TCGA |
|
rs749064025 CA290082176 |
236 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757624583 CA290082155 |
239 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1555604990 CA399149558 |
240 | H>N | No |
ClinGen gnomAD |
|
|
CA290082148 rs370434781 |
240 | H>Q | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs758475977 CA290082143 |
241 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs758475977 CA399149551 |
241 | E>Q | No |
ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 243 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399149536 rs1555604979 |
243 | G>R | No |
gnomAD ClinGen |
|
|
CA290082116 rs755557404 |
244 | H>Q | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290082115 rs754121685 |
245 | T>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 246 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290082099 rs750115316 |
247 | G>D | No |
ExAC TOPMed ClinGen |
|
|
CA290082093 rs767071995 |
248 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA399149497 rs1555604961 |
250 | H>N | No |
gnomAD ClinGen |
|
|
rs761264052 CA290082084 |
250 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA290082089 rs970234000 |
250 | H>R | No |
ClinGen Ensembl |
|
|
rs372470385 CA290082083 |
251 | S>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA290082055 rs564376727 |
251 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
1000Genomes ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
CA399149491 rs372470385 |
251 | S>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs564376727 CA399149488 |
251 | S>W | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290082045 rs775131064 |
253 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs373798048 CA290082042 |
254 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA399149472 rs373798048 |
254 | P>R | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
CA290082040 rs747166219 |
255 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747166219 CA290082039 |
255 | R>G | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1386501340 CA399149468 |
255 | R>L | No |
TOPMed ClinGen |
|
|
rs1598425691 CA399149467 |
256 | A>S | No |
ClinGen Ensembl |
|
|
CA399149462 rs1598425675 |
256 | A>V | No |
Ensembl ClinGen |
|
|
rs772090801 CA290082029 |
259 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
|
rs1318313803 CA399149440 |
260 | P>A | No |
TOPMed ClinGen |
|
|
CA290082027 rs1040058004 |
260 | P>R | No |
TOPMed ClinGen |
|
|
CA399149432 rs1555604889 |
261 | Y>C | No |
gnomAD ClinGen |
|
|
CA399149435 rs1555604891 |
261 | Y>H | No |
gnomAD ClinGen |
|
|
CA290082011 rs573037463 |
262 | Y>C | No |
ClinGen 1000Genomes gnomAD |
|
|
rs779090998 CA290082019 |
262 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs755436729 CA290082008 |
263 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399149408 rs1347375733 |
265 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
TOPMed ClinGen NCI-TCGA |
|
rs1555604866 CA399149395 |
267 | R>C | No |
gnomAD ClinGen |
|
|
CA290081986 rs756554998 |
267 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA399149390 rs1555604856 |
268 | D>Y | No |
ClinGen gnomAD |
|
|
rs1555604852 CA399149383 |
269 | A>T | No |
gnomAD ClinGen |
|
|
rs750058315 CA290081961 |
269 | A>V | No |
ExAC gnomAD ClinGen |
|
|
rs1050820246 CA290081951 |
270 | L>Q | No |
Ensembl ClinGen |
|
|
CA399149378 rs1261000457 |
270 | L>V | No |
ClinGen TOPMed |
|
|
rs767304856 TCGA novel CA290081941 |
273 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ExAC gnomAD ClinGen |
|
CA290081934 rs756987596 |
274 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
|
CA399149345 rs1555604842 |
275 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
gnomAD ClinGen NCI-TCGA |
|
rs1468734170 CA399149340 |
275 | D>V | No |
ClinGen TOPMed |
|
|
CA290081923 rs751024631 |
277 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs1195215320 CA399149324 |
278 | A>V | No |
TOPMed ClinGen |
|
|
rs759347423 CA399149316 |
279 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759347423 CA290081868 |
279 | V>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764976085 CA290081881 |
279 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA290081888 rs764976085 |
279 | V>M | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 280 | Q>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs776458981 CA290081866 |
281 | S>R | No |
ExAC gnomAD ClinGen |
|
|
CA290081863 rs774281780 |
282 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774281780 CA290081862 |
282 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761885135 CA290080641 |
285 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs1431256272 CA399148381 |
286 | P>T | No |
TOPMed gnomAD ClinGen |
|
| TCGA novel | 288 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290080624 rs759609205 |
289 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs759609205 CA290080634 |
289 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
|
CA399148349 rs774639772 |
289 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
|
CA290080640 rs774639772 |
289 | G>S | No |
ExAC gnomAD ClinGen |
|
|
rs759609205 CA290080623 |
289 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA290080606 rs771327669 |
293 | V>A | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs375879517 CA290080611 |
293 | V>I | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs539729285 CA290080601 |
296 | P>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs929595282 CA290080605 |
296 | P>S | No |
Ensembl ClinGen |
|
|
CA290080596 rs267604816 |
297 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
Ensembl ClinGen NCI-TCGA |
|
CA290080593 rs777501875 |
298 | K>R | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 300 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs758034658 CA290080587 |
301 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1568137487 CA399148224 |
302 | D>N | No |
ClinGen Ensembl |
|
|
CA399148188 rs1555604280 |
306 | W>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1555604271 CA399148164 |
309 | Y>* | No |
ClinGen gnomAD |
|
| TCGA novel | 310 | S>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs778460768 CA290080579 |
311 | P>S | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 312 | Q>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290080560 rs570864449 |
314 | R>S | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
rs751685683 CA290080543 |
315 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs368500708 CA290080538 |
315 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA290080535 rs368500708 |
315 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs751685683 CA290080552 |
315 | R>S | No |
ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 317 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290080511 rs370540313 |
318 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1555604253 CA399148107 |
319 | Q>* | No |
ClinGen gnomAD |
|
|
rs760049945 CA290080495 |
320 | G>V | No |
ExAC gnomAD ClinGen |
|
|
rs1555604245 CA399148094 |
321 | P>S | No |
gnomAD ClinGen |
|
|
CA290080460 rs76254587 |
323 | Y>S | No |
ClinGen Ensembl |
|
| TCGA novel | 327 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 328 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs773488573 CA290080450 |
329 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 329 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290080458 rs747375514 |
329 | D>Y | No |
ExAC ClinGen |
|
|
CA290080443 rs747857027 |
331 | I>F | No |
ExAC gnomAD ClinGen |
|
|
rs752969197 CA290080123 |
334 | D>G | No |
ExAC gnomAD ClinGen |
|
|
rs765365910 CA290080122 |
336 | Q>* | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs765365910 CA399147982 |
336 | Q>K | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290080120 rs200216940 |
337 | Q>* | No |
ClinGen gnomAD |
|
|
CA399147966 rs1322176218 |
338 | Q>K | No |
ClinGen TOPMed |
|
|
CA399147951 rs1555604114 |
340 | Y>C | No |
gnomAD ClinGen |
|
|
rs1263365026 CA399147904 |
346 | H>R | No |
ClinGen TOPMed |
|
| TCGA novel | 347 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290080053 rs761151588 |
349 | E>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 351 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399147846 rs1555604103 |
354 | G>D | No |
ClinGen gnomAD |
|
|
CA399147848 rs1555604105 |
354 | G>S | No |
ClinGen gnomAD |
|
|
CA399147836 rs376963669 |
355 | N>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA290080023 rs373546365 |
356 | V>F | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs373546365 CA290080028 |
356 | V>I | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs373546365 CA290080018 |
356 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA290080011 rs768108095 |
357 | S>L | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 358 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs371440451 CA290080005 |
360 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA290080004 rs201181477 |
360 | R>H | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 361 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290079992 rs376846489 |
363 | Q>H | No |
ESP ExAC gnomAD ClinGen |
|
| TCGA novel | 364 | E>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399147766 rs1598419099 |
367 | V>L | No |
Ensembl ClinGen |
|
|
CA290079977 rs755290122 |
368 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290079970 rs755290122 |
368 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1555604039 CA399147752 |
370 | P>S | No |
ClinGen gnomAD |
|
|
rs753946857 CA290079965 |
371 | P>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399147742 rs753946857 |
371 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs750644158 | 372 | N>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290079958 rs1035217182 |
373 | I>L | No |
TOPMed gnomAD ClinGen |
|
|
rs1276145863 CA399147730 |
373 | I>T | No |
ClinGen TOPMed |
|
|
rs766427332 CA290079956 |
375 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399147719 rs766427332 |
375 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs369105121 CA399147711 |
376 | A>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1257046802 CA399147714 |
376 | A>T | No |
TOPMed ClinGen |
|
|
CA290079954 rs369105121 |
376 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA399147708 rs1555604004 |
377 | A>T | No |
ClinGen gnomAD |
|
|
CA290079910 rs762189335 |
378 | V>M | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 381 | N>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290079881 rs762583584 |
382 | D>V | No |
ExAC gnomAD ClinGen |
|
|
rs1190825470 CA399147669 |
383 | G>R | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 385 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs775056613 CA290079873 |
386 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 388 | F>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 389 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290079867 rs745774492 |
389 | K>R | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs966593744 CA290079865 |
390 | G>R | No |
ClinGen Ensembl |
|
|
CA290079184 rs775032482 |
391 | G>V | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs769311015 CA290079161 |
392 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290079154 rs558972752 |
392 | R>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA399147559 rs1343516538 |
393 | C>S | No |
TOPMed gnomAD ClinGen |
|
|
CA399147550 rs1555603646 |
394 | W>* | No |
gnomAD ClinGen |
|
|
CA290079153 CA290079152 rs539276001 |
394 | W>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
1000Genomes ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs770980548 CA290079146 |
395 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA290079109 rs777645399 |
397 | R>Q | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290079120 rs570288318 |
397 | R>W | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
rs1356617694 CA399147525 |
398 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
CA290079101 rs771776742 |
398 | G>D | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1356617694 CA399147527 |
398 | G>S | No |
TOPMed gnomAD ClinGen |
|
|
CA399147518 rs1288984053 |
399 | P>R | No |
ClinGen TOPMed |
|
|
rs780170095 CA290079097 |
401 | P>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399147508 rs780170095 |
401 | P>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs868853158 CA290079090 |
402 | V>L | No |
Ensembl ClinGen |
|
|
CA290079084 rs866619470 |
403 | W>C | No |
ClinGen Ensembl |
|
|
rs1254409698 CA399147490 |
404 | G>S | No |
TOPMed ClinGen |
|
| TCGA novel | 405 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290079079 rs75119129 |
405 | L>P | No |
Ensembl ClinGen |
|
|
rs1555603592 CA399147474 |
406 | P>L | No |
ClinGen gnomAD |
|
|
CA399147466 rs1417760367 |
407 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
CA399147452 rs756397870 |
410 | R>G | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs750478027 CA399147451 |
410 | R>P | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290079072 rs750478027 |
410 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290079073 rs756397870 |
410 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781304210 CA399147445 |
411 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290079071 rs781304210 |
411 | A>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399147432 rs1555603564 |
412 | G>E | No |
ClinGen gnomAD |
|
|
CA399147426 rs1598415813 |
413 | G>S | No |
ClinGen Ensembl |
|
|
CA399147401 rs751609610 |
415 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA290079059 rs751609610 |
415 | P>T | No |
TOPMed gnomAD ClinGen |
|
|
CA290079048 rs533824994 |
416 | R>C | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA399147388 rs1312239488 |
416 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1555603534 CA399147379 |
417 | H>R | No |
gnomAD ClinGen |
|
|
CA399147364 rs1358187204 |
418 | P>L | No |
TOPMed ClinGen |
|
| TCGA novel | 418 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs200933511 CA399147345 |
419 | D>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs758725453 CA290079023 |
420 | A>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290079012 rs867571976 |
420 | A>V | No |
gnomAD ClinGen |
|
|
CA290079003 rs371940194 |
421 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs370737986 CA290078998 |
423 | F>L | No |
ESP TOPMed ClinGen |
|
|
CA399147273 rs1257363015 |
425 | P>L | No |
TOPMed ClinGen |
|
|
CA399147279 rs1555603491 |
425 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
gnomAD ClinGen NCI-TCGA |
|
rs764777782 CA290078996 |
426 | P>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290078995 rs759293292 |
427 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs367820262 CA290078994 |
428 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ESP ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs765992640 CA290078993 |
428 | R>H | Variant assessed as Somatic; 6.025e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA399147246 rs765992640 |
428 | R>L | No |
ExAC gnomAD ClinGen |
|
|
rs367820262 CA399147253 |
428 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs760632184 CA290078984 |
429 | R>C | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290078983 rs773304036 |
429 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399147238 rs773304036 |
429 | R>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs760632184 CA399147244 |
429 | R>S | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs964011123 CA290078977 |
430 | L>R | No |
TOPMed gnomAD ClinGen |
|
|
rs1334347837 CA399147158 |
436 | A>T | No |
TOPMed ClinGen |
|
|
rs1381598439 CA399147142 |
437 | R>C | No |
TOPMed gnomAD ClinGen |
|
|
CA399147140 rs774249689 |
437 | R>H | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs774249689 CA399147137 |
437 | R>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290078953 rs774249689 |
437 | R>P | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1381598439 CA399147146 |
437 | R>S | No |
TOPMed gnomAD ClinGen |
|
|
CA399147105 rs769891235 |
440 | V>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290078943 rs769891235 |
440 | V>M | No |
ExAC TOPMed gnomAD ClinGen |
|
| TCGA novel | 442 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs369027708 CA290078940 |
443 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290078941 rs369027708 |
443 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781178488 CA290078939 |
443 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs1598415137 CA399147064 |
444 | G>E | No |
ClinGen Ensembl |
|
| TCGA novel | 445 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399147059 rs1555603417 |
445 | G>R | No |
ClinGen gnomAD |
|
|
rs757338388 CA290078903 |
446 | L>P | No |
ExAC gnomAD ClinGen |
|
|
CA290078880 rs901634099 |
447 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
rs747477806 CA290078874 |
448 | V>M | No |
ExAC gnomAD ClinGen |
|
|
CA290078864 rs778115477 |
449 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs758996305 CA290078858 |
450 | P>L | No |
ExAC gnomAD ClinGen |
|
|
rs754612478 CA290078852 |
453 | P>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290078854 rs138254597 |
453 | P>S | No |
1000Genomes ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs1555603380 CA919831620 |
453 | P>S | No |
ClinGen Ensembl |
|
|
CA399146976 rs138254597 |
453 | P>T | No |
1000Genomes ESP ExAC TOPMed gnomAD ClinGen |
|
|
CA290078850 rs765937653 |
454 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs760292726 CA290078844 |
454 | R>Q | No |
ExAC TOPMed ClinGen |
|
| TCGA novel | 457 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 457 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290078843 rs531295060 |
459 | W>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1302517657 CA399146929 |
460 | G>R | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 463 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA399146884 rs1555603361 |
463 | P>L | No |
gnomAD ClinGen |
|
|
CA399146867 rs1314466913 |
465 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs761866090 CA290078835 |
465 | E>V | No |
ExAC gnomAD ClinGen |
|
| TCGA novel | 466 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA290078808 rs768499454 |
468 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA290078784 rs776873799 |
469 | A>D | No |
ClinGen ExAC gnomAD |
|
|
rs1555603342 CA399146830 |
469 | A>P | No |
gnomAD ClinGen |
|
|
rs1555603342 CA399146832 |
469 | A>T | No |
ClinGen gnomAD |
|
|
CA290078759 rs771185619 |
471 | P>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs777969136 CA290078751 |
472 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA290078737 rs532783200 |
474 | D>N | No |
1000Genomes ExAC TOPMed gnomAD ClinGen |
|
|
CA290078727 rs753502013 |
475 | G>A | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs753502013 CA290078730 |
475 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399146765 rs1191857446 |
475 | G>S | No |
TOPMed gnomAD ClinGen |
|
|
rs753502013 CA290078720 |
475 | G>V | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1481393295 CA399146746 |
477 | I>L | No |
ClinGen TOPMed |
|
|
CA290078717 rs779820951 |
478 | I>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA290078718 rs779820951 |
478 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA399146700 rs1428393563 |
481 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1012437556 CA290078702 |
481 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs755879354 CA290078691 |
484 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290078685 rs1053381994 |
484 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
TOPMed gnomAD ClinGen NCI-TCGA |
|
rs1555603303 CA399146339 |
485 | Y>H | No |
ClinGen gnomAD |
|
|
CA290078673 rs767119397 |
486 | W>C | No |
ExAC gnomAD ClinGen |
|
|
rs75045636 CA290078669 |
487 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA290078668 rs372991755 |
487 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA399146320 rs372991755 |
487 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1283006246 CA399146315 |
488 | L>P | No |
ClinGen TOPMed |
|
|
rs775316487 CA290078649 |
489 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762709550 CA290078660 |
489 | D>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762709550 CA399146312 |
489 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs771132233 CA290078639 |
490 | Q>R | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1555603259 CA399146295 |
491 | A>V | No |
gnomAD ClinGen |
|
|
rs1555603256 CA399146278 |
494 | Q>P | No |
gnomAD ClinGen |
|
| TCGA novel | 495 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 495 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs772206617 CA290078630 |
497 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs779505830 CA290078614 |
498 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290078620 rs779505830 |
498 | S>W | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs375047060 CA290078548 |
500 | R>C | No |
ESP ExAC TOPMed gnomAD ClinGen |
|
|
rs146307755 CA290078543 |
500 | R>H | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs146307755 CA399146244 |
500 | R>L | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs146307755 CA290078538 |
500 | R>P | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA290078530 rs750091428 |
502 | A>G | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs756809910 CA290078517 |
504 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA290078505 rs371276704 |
506 | P>S | No |
Ensembl ClinGen |
|
|
CA399146184 rs1366940211 |
509 | G>A | No |
TOPMed ClinGen |
|
|
rs751074222 CA290078500 |
510 | C>S | No |
ExAC gnomAD ClinGen |
|
|
CA399146168 rs1555603217 |
511 | W>C | No |
gnomAD ClinGen |
|
|
CA290078491 rs763999932 |
512 | H>P | No |
ClinGen ExAC gnomAD |
|
|
rs762938904 CA290078475 |
513 | A>T | No |
ExAC TOPMed gnomAD ClinGen |
|
|
rs1555603204 CA399146147 |
514 | N>K | No |
ClinGen gnomAD |
|
|
CA290078471 rs760538429 |
515 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA290078472 rs760538429 |
515 | S>L | No |
ExAC TOPMed gnomAD ClinGen |
|
|
CA399146143 rs760538429 |
515 | S>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1555603195 CA399146126 |
518 | A>D | No |
gnomAD ClinGen |
|
|
rs540421800 CA290078463 |
518 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
CA399146124 rs1555603195 |
518 | A>V | No |
ClinGen gnomAD |
|
|
rs1555603189 CA399146114 |
520 | F>C | No |
gnomAD ClinGen |
|
| TCGA novel | 521 | F>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
No associated diseases with Q9H239
9 regional properties for Q9H239
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Hemopexin-like domain | 321 - 510 | IPR000585 |
| domain | Peptidase M10, metallopeptidase | 129 - 284 | IPR001818 |
| domain | Peptidoglycan binding-like | 33 - 86 | IPR002477 |
| domain | Peptidase, metallopeptidase | 126 - 285 | IPR006026 |
| repeat | Hemopexin-like repeats | 325 - 371 | IPR018487-1 |
| repeat | Hemopexin-like repeats | 370 - 416 | IPR018487-2 |
| repeat | Hemopexin-like repeats | 415 - 464 | IPR018487-3 |
| repeat | Hemopexin-like repeats | 466 - 510 | IPR018487-4 |
| domain | Peptidase M10A, catalytic domain | 129 - 284 | IPR033739 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| collagen-containing extracellular matrix | An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| extracellular matrix | A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. |
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metalloendopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
| zinc ion binding | Binding to a zinc ion (Zn). |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| collagen catabolic process | The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. |
| extracellular matrix organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. |
| negative regulation of macrophage chemotaxis | Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3SZV7 | HPX | Hemopexin | Bos taurus (Bovine) | PR |
| O77656 | MMP13 | Collagenase 3 | Bos taurus (Bovine) | PR |
| Q9GLE5 | MMP2 | 72 kDa type IV collagenase | Bos taurus (Bovine) | PR |
| Q90611 | MMP2 | 72 kDa type IV collagenase | Gallus gallus (Chicken) | PR |
| Q8MPP3 | Mmp2 | Matrix metalloproteinase-2 | Drosophila melanogaster (Fruit fly) | PR |
| P04004 | VTN | Vitronectin | Homo sapiens (Human) | PR |
| Q99542 | MMP19 | Matrix metalloproteinase-19 | Homo sapiens (Human) | PR |
| Q9NPA2 | MMP25 | Matrix metalloproteinase-25 | Homo sapiens (Human) | PR |
| P45452 | MMP13 | Collagenase 3 | Homo sapiens (Human) | PR |
| P34960 | Mmp12 | Macrophage metalloelastase | Mus musculus (Mouse) | PR |
| P33435 | Mmp13 | Collagenase 3 | Mus musculus (Mouse) | PR |
| P33434 | Mmp2 | 72 kDa type IV collagenase | Mus musculus (Mouse) | PR |
| P28862 | Mmp3 | Stromelysin-1 | Mus musculus (Mouse) | PR |
| P23097 | Mmp13 | Collagenase 3 | Rattus norvegicus (Rat) | PR |
| Q63341 | Mmp12 | Macrophage metalloelastase | Rattus norvegicus (Rat) | PR |
| P33436 | Mmp2 | 72 kDa type IV collagenase | Rattus norvegicus (Rat) | PR |
| Q6PHG2 | hpx | Hemopexin | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVARVGLLLR | ALQLLLWGHL | DAQPAERGGQ | ELRKEAEAFL | EKYGYLNEQV | PKAPTSTRFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DAIRAFQWVS | QLPVSGVLDR | ATLRQMTRPR | CGVTDTNSYA | AWAERISDLF | ARHRTKMRRK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KRFAKQGNKW | YKQHLSYRLV | NWPEHLPEPA | VRGAVRAAFQ | LWSNVSALEF | WEAPATGPAD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IRLTFFQGDH | NDGLGNAFDG | PGGALAHAFL | PRRGEAHFDQ | DERWSLSRRR | GRNLFVVLAH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EIGHTLGLTH | SPAPRALMAP | YYKRLGRDAL | LSWDDVLAVQ | SLYGKPLGGS | VAVQLPGKLF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TDFETWDSYS | PQGRRPETQG | PKYCHSSFDA | ITVDRQQQLY | IFKGSHFWEV | AADGNVSEPR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PLQERWVGLP | PNIEAAAVSL | NDGDFYFFKG | GRCWRFRGPK | PVWGLPQLCR | AGGLPRHPDA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ALFFPPLRRL | ILFKGARYYV | LARGGLQVEP | YYPRSLQDWG | GIPEEVSGAL | PRPDGSIIFF |
| 490 | 500 | 510 | |||
| RDDRYWRLDQ | AKLQATTSGR | WATELPWMGC | WHANSGSALF |