Q84TF0
Gene name |
AKR4C10 (At2g37790, T8P21.30) |
Protein name |
Aldo-keto reductase family 4 member C10 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G37790 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q84TF0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q84TF0-F1 | Predicted | AlphaFoldDB |
27 variants for Q84TF0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13564696 | 33 | N>K | No | 1000Genomes | |
| ENSVATH14593957 | 38 | A>S | No | 1000Genomes | |
| ENSVATH13564700 | 41 | I>F | No | 1000Genomes | |
| ENSVATH13564700 | 41 | I>V | No | 1000Genomes | |
| ENSVATH01961985 | 53 | G>S | No | 1000Genomes | |
| ENSVATH01961996 | 61 | V>A | No | 1000Genomes | |
| ENSVATH01961998 | 68 | G>D | No | 1000Genomes | |
| ENSVATH01962005 | 106 | D>H | No | 1000Genomes | |
| tmp_2_15839964_T_A | 117 | V>D | No | 1000Genomes | |
| ENSVATH01962010 | 137 | P>S | No | 1000Genomes | |
| tmp_2_15840069_C_T | 152 | A>V | No | 1000Genomes | |
| tmp_2_15840071_C_G | 153 | R>G | No | 1000Genomes | |
| ENSVATH01962011 | 170 | V>A | No | 1000Genomes | |
| ENSVATH13564723 | 199 | K>E | No | 1000Genomes | |
| tmp_2_15840224_T_G | 204 | S>A | No | 1000Genomes | |
| ENSVATH01962023 | 218 | T>K | No | 1000Genomes | |
| tmp_2_15840373_C_A | 225 | P>H | No | 1000Genomes | |
| tmp_2_15840402_G_A | 235 | G>S | No | 1000Genomes | |
| tmp_2_15840429_C_T | 244 | R>C | No | 1000Genomes | |
| ENSVATH05673436 | 265 | Q>H | No | 1000Genomes | |
| ENSVATH05673437 | 268 | D>N | No | 1000Genomes | |
| ENSVATH05673437 | 268 | D>Y | No | 1000Genomes | |
| ENSVATH01962031 | 276 | E>D | No | 1000Genomes | |
| tmp_2_15840536_A_C | 279 | L>F | No | 1000Genomes | |
| ENSVATH01962032 | 286 | G>E | No | 1000Genomes | |
| tmp_2_15840703_A_G | 299 | E>G | No | 1000Genomes | |
| ENSVATH13564747 | 303 | Y>C | No | 1000Genomes |
No associated diseases with Q84TF0
7 regional properties for Q84TF0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 10 - 204 | IPR000795 |
| domain | Translation elongation factor EFTu/EF1A, C-terminal | 298 - 392 | IPR004160 |
| domain | Translation elongation factor EFTu-like, domain 2 | 225 - 293 | IPR004161 |
| domain | Small GTP-binding protein domain | 13 - 148 | IPR005225 |
| conserved_site | Tr-type G domain, conserved site | 51 - 66 | IPR031157 |
| domain | Elongation factor Tu, domain 2 | 211 - 297 | IPR033720 |
| domain | Elongation factor Tu (EF-Tu), GTP-binding domain | 11 - 203 | IPR041709 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| alditol:NADP+ 1-oxidoreductase activity | Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P16116 | AKR1B1 | Aldo-keto reductase family 1 member B1 | Bos taurus (Bovine) | PR |
| O60218 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Homo sapiens (Human) | PR |
| P15121 | AKR1B1 | Aldo-keto reductase family 1 member B1 | Homo sapiens (Human) | PR |
| P45376 | Akr1b1 | Aldo-keto reductase family 1 member B1 | Mus musculus (Mouse) | PR |
| P45377 | Akr1b8 | Aldose reductase-related protein 2 | Mus musculus (Mouse) | PR |
| P80276 | AKR1B1 | Aldo-keto reductase family 1 member B1 | Sus scrofa (Pig) | PR |
| P07943 | Akr1b1 | Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Rat) | PR |
| Q9M338 | AKR4C11 | Aldo-keto reductase family 4 member C11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0PGJ6 | AKR4C9 | NADPH-dependent aldo-keto reductase, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80944 | AKR4C8 | Aldo-keto reductase family 4 member C8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEEIRFFEL | NTGAKIPSVG | LGTWQADPGL | VGNAVDAAVK | IGYRHIDCAQ | IYGNEKEIGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLKKLFDGGV | VKREEMFITS | KLWCTYHDPQ | EVPEALNRTL | QDLQLDYVDL | YLIHWPVSLK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGSTGFKPEN | ILPTDIPSTW | KAMESLFDSG | KARAIGVSNF | SSKKLADLLV | VARVPPAVNQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VECHPSWQQN | VLRDFCKSKG | VHLSGYSPLG | SPGTTWLTSD | VLKNPILGGV | AEKLGKTPAQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VALRWGLQMG | QSVLPKSTHE | DRIKQNFDVF | NWSIPEDMLS | KFSEIGQGRL | VRGMSFVHET |
| 310 | |||||
| SPYKSLEELW | DGEI |