Q6ZMY6
PR
Gene name |
WDR88 (PQWD) |
Protein name |
WD repeat-containing protein 88 |
Names |
PQQ repeat and WD repeat-containing protein |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:126248 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6ZMY6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6ZMY6-F1 | Predicted | AlphaFoldDB |
387 variants for Q6ZMY6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA405220179 rs1407134666 |
2 | A>T | No |
ClinGen TOPMed |
|
|
rs1303046117 CA405220193 |
3 | S>C | No |
ClinGen TOPMed |
|
|
rs746842354 CA9361839 |
3 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781080516 CA9361841 |
4 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405220221 rs1256842277 |
6 | R>Q | No |
ClinGen gnomAD |
|
|
rs1203946416 CA405220217 |
6 | R>W | No |
ClinGen gnomAD |
|
|
CA9361844 rs774336672 |
7 | C>* | No |
ClinGen ExAC gnomAD |
|
|
rs1206534877 CA405220228 |
7 | C>F | No |
ClinGen gnomAD |
|
| TCGA novel | 7 | C>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9361843 rs769818307 |
7 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs774336672 CA405220229 |
7 | C>W | No |
ClinGen ExAC gnomAD |
|
|
CA9361846 rs772240791 |
9 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA307537047 rs772240791 |
9 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
rs761933539 CA9361845 |
9 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs766752473 CA9361849 |
10 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs766752473 CA9361850 |
10 | T>K | No |
ClinGen ExAC gnomAD |
|
|
CA405220270 rs1395856779 |
12 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1408211658 CA405220290 |
14 | R>K | No |
ClinGen gnomAD |
|
|
CA9361852 rs765750241 |
15 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361851 rs760075210 |
15 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA9361853 rs752205154 |
16 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1404911037 CA405220307 |
16 | C>R | No |
ClinGen gnomAD |
|
|
rs900682050 CA307537056 |
19 | P>L | No |
ClinGen Ensembl |
|
|
CA9361854 rs563701169 |
20 | P>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA405220363 rs1267965453 |
21 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA307537061 rs996390125 |
22 | S>F | No |
ClinGen Ensembl |
|
|
CA307537065 rs751241166 |
23 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405220373 rs1337049568 |
23 | A>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1337049568 CA405220376 |
23 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA9361856 rs751241166 |
23 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756925010 CA9361857 |
24 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1273130095 CA405220381 |
24 | P>S | No |
ClinGen gnomAD |
|
|
CA405220410 rs1220216842 |
27 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9361858 rs781166699 |
29 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs745629907 CA9361859 |
30 | P>L | No |
ClinGen ExAC gnomAD |
|
|
COSM3388843 COSM3388844 CA9361861 rs371696429 |
31 | G>S | pancreas [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA9361862 rs748242710 |
36 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA9361863 rs772198262 |
40 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs375921114 CA307537081 |
41 | A>V | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs529290113 CA9361865 |
44 | R>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9361864 rs773116014 |
44 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361866 rs771109571 |
47 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs777027370 CA9361867 |
48 | S>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1429992280 CA405220645 |
50 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1429992280 CA405220642 |
50 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1358168441 CA405220651 |
51 | H>P | No |
ClinGen gnomAD |
|
|
rs763306931 CA405220657 |
51 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA9361870 rs201338259 |
51 | H>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1360086914 CA405220677 |
53 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA405220699 rs1204276375 |
56 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs763686538 CA405220715 |
58 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361872 rs763686538 |
58 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA307537100 rs957991386 |
59 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA405220724 rs1445461024 |
59 | D>Y | No |
ClinGen gnomAD |
|
|
rs1161757722 CA405220752 |
62 | A>S | No |
ClinGen gnomAD |
|
|
CA405220783 rs1568355306 |
65 | R>G | No |
ClinGen Ensembl |
|
|
CA9361875 rs757012981 |
66 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1158316326 CA405220817 |
68 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA405220830 rs1225536837 |
69 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA405220823 rs1383311220 |
69 | P>S | No |
ClinGen gnomAD |
|
|
CA405220869 rs1374708010 |
73 | P>L | No |
ClinGen TOPMed |
|
|
rs1449758006 CA405220899 |
76 | H>N | No |
ClinGen gnomAD |
|
|
CA405220926 rs755933546 |
78 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA9361878 rs755933546 |
78 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA405220940 rs1238290762 |
79 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA405220952 rs1258712610 |
80 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9361879 rs779648023 |
82 | L>M | No |
ClinGen ExAC gnomAD |
|
|
CA307537116 rs751606015 |
84 | W>* | No |
ClinGen Ensembl |
|
|
rs749269993 CA9361880 |
85 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs1014688532 CA405221016 |
87 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
CA307537121 rs1014688532 |
87 | Q>E | No |
ClinGen TOPMed gnomAD |
|
|
CA405221043 rs1181781858 |
89 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA405221045 rs1181781858 |
89 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA307537129 rs969863558 |
91 | S>T | No |
ClinGen Ensembl |
|
|
CA405221430 rs1599879406 |
93 | I>T | No |
ClinGen Ensembl |
|
|
CA9361907 rs147156559 COSM710391 |
95 | F>L | lung [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
| TCGA novel | 98 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs775965034 CA9361909 |
99 | S>N | No |
ClinGen ExAC gnomAD |
|
|
TCGA novel rs1206564433 CA405221472 |
99 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen gnomAD |
|
CA9361910 rs749596712 |
101 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361912 rs774996368 |
102 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs140302466 CA9361914 |
102 | E>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9361913 rs774996368 |
102 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA307538478 rs931699319 |
103 | H>Y | No |
ClinGen TOPMed |
|
|
rs753724422 CA9361920 |
104 | A>D | No |
ClinGen ExAC |
|
|
rs753724422 CA9361919 |
104 | A>G | No |
ClinGen ExAC |
|
|
rs114139486 CA9361917 |
104 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs114139486 CA9361916 |
104 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs753724422 CA9361918 |
104 | A>V | No |
ClinGen ExAC |
|
|
CA9361922 rs758279288 |
105 | V>G | No |
ClinGen ExAC |
|
|
CA405221499 rs752641881 |
105 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361921 rs752641881 |
105 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780129522 CA9361927 |
106 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs756412352 CA9361925 |
106 | S>R | No |
ClinGen ExAC |
|
|
rs780129522 CA9361926 |
106 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs200077528 CA9361928 |
107 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA405221541 rs1363482947 |
111 | C>S | No |
ClinGen gnomAD |
|
|
CA405221562 rs779365271 |
114 | D>A | No |
ClinGen ExAC gnomAD |
|
|
CA9361929 rs779365271 |
114 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA405221574 rs1368521940 |
116 | K>* | No |
ClinGen gnomAD |
|
| TCGA novel | 116 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1381903285 CA405221576 |
116 | K>R | No |
ClinGen gnomAD |
|
|
COSM78777 rs772675231 CA9361931 |
119 | S>C | ovary [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1599879521 CA405221615 |
122 | Y>H | No |
ClinGen Ensembl |
|
|
CA405221619 rs1599879524 |
122 | Y>S | No |
ClinGen Ensembl |
|
|
CA9361933 rs760089262 |
123 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs543234357 CA9361934 |
124 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9361935 rs776149136 |
125 | T>P | No |
ClinGen ExAC TOPMed |
|
| TCGA novel | 126 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 127 | K>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 128 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9361936 rs759166123 |
128 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361937 rs765035730 |
129 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs1568358367 CA405221709 |
129 | W>S | No |
ClinGen Ensembl |
|
|
CA405223105 rs1222372306 |
130 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs778138509 CA9361967 |
131 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1202690246 CA405223137 |
132 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1260687034 CA405223140 |
133 | D>N | No |
ClinGen gnomAD |
|
|
COSM3764728 COSM3764727 rs924796394 CA307539302 |
134 | G>S | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
COSM994679 rs201739777 CA9361971 |
138 | R>C | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 138 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405223205 rs1178683132 |
138 | R>L | No |
ClinGen gnomAD |
|
|
COSM994680 rs866791537 CA307539303 |
139 | D>N | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs775123698 CA9361973 |
141 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA9361975 rs768349048 |
143 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361976 rs774148373 |
145 | K>T | No |
ClinGen ExAC gnomAD |
|
|
CA405223302 rs1294613845 |
146 | A>P | No |
ClinGen TOPMed |
|
|
rs761688962 CA9361977 |
147 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361978 rs556019352 |
152 | S>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA405223392 rs1599887326 |
154 | T>P | No |
ClinGen Ensembl |
|
|
rs759683512 CA405223406 |
155 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759683512 CA9361980 |
155 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9361983 rs758640744 |
156 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3357110 CA405223416 rs148478015 COSM2751399 |
156 | D>N | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs148478015 CA9361982 |
156 | D>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs370627703 CA9362010 |
163 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
| VAR_035892 | 166 | D>H | a breast cancer sample; somatic mutation [UniProt] | No | UniProt |
|
rs1483589630 CA405223627 |
166 | D>N | No |
ClinGen TOPMed |
|
|
rs779572529 CA9362012 |
167 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA9362013 CA405223640 rs753316645 |
167 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1208876423 CA405223643 |
168 | T>A | No |
ClinGen TOPMed |
|
|
rs74994260 CA9362014 |
171 | A>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9362015 rs778621044 |
174 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs374055138 CA9362016 |
176 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA405223699 rs1266968697 |
177 | G>S | No |
ClinGen gnomAD |
|
|
rs1314726939 CA405223704 |
177 | G>V | No |
ClinGen TOPMed |
|
|
rs771914123 CA9362017 |
178 | K>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1428168027 CA405223805 |
181 | W>* | No |
ClinGen gnomAD |
|
|
CA9362042 rs774250848 |
183 | V>G | No |
ClinGen ExAC gnomAD |
|
|
rs1402770829 CA405223838 |
184 | R>M | No |
ClinGen gnomAD |
|
|
CA405223844 rs1486113529 |
184 | R>S | No |
ClinGen TOPMed |
|
|
CA405223852 rs1390787414 |
185 | Y>D | No |
ClinGen gnomAD |
|
|
CA9362044 rs772252424 |
188 | F>V | No |
ClinGen ExAC gnomAD |
|
|
rs902564871 CA307539716 |
189 | I>V | No |
ClinGen TOPMed |
|
|
CA9362046 COSM1712129 rs144304527 |
190 | V>I | skin [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs977301033 CA307539717 |
191 | S>C | No |
ClinGen Ensembl |
|
|
rs199681301 CA9362047 |
192 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9362048 rs146562379 |
193 | K>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs964934511 CA307539718 |
195 | S>A | No |
ClinGen TOPMed |
|
|
rs1568363565 CA405224053 |
196 | P>R | No |
ClinGen Ensembl |
|
|
CA405224041 rs1231101220 |
196 | P>T | No |
ClinGen gnomAD |
|
|
rs764829746 CA9362050 |
201 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1195781744 CA405224205 |
204 | G>A | No |
ClinGen gnomAD |
|
|
rs752113451 CA9362051 |
205 | F>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405224217 rs752113451 |
205 | F>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1599892558 CA405224212 |
205 | F>V | No |
ClinGen Ensembl |
|
|
rs141262115 CA9362054 |
206 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
COSM1392653 rs757075743 CA9362053 |
206 | D>N | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA9362056 rs781080393 |
207 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA405224299 rs1183614787 |
209 | H>R | No |
ClinGen TOPMed |
|
|
rs779091057 CA9362059 |
211 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1461407337 CA405224371 |
213 | I>V | No |
ClinGen gnomAD |
|
|
rs1372336471 CA405224396 |
214 | M>K | No |
ClinGen gnomAD |
|
|
rs1166155145 CA405224395 |
214 | M>L | No |
ClinGen gnomAD |
|
|
rs1372336471 CA405224400 |
214 | M>R | No |
ClinGen gnomAD |
|
|
CA9362061 COSM994681 rs772340255 |
216 | A>T | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA9362062 rs773425928 |
216 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs574958369 CA9362065 |
217 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA9362064 rs771306190 |
217 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 219 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405224518 rs1354307443 |
220 | T>I | No |
ClinGen TOPMed |
|
|
CA307539720 rs771491162 |
221 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs201611292 CA9362066 |
222 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9362067 rs765636472 |
223 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA9362069 rs138538856 COSM3959900 COSM1392654 |
224 | V>I | lung large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA9362070 rs763634191 |
227 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs1318593010 CA405211159 |
227 | D>V | No |
ClinGen gnomAD |
|
|
CA405211187 rs1390996134 |
229 | H>Q | No |
ClinGen gnomAD |
|
|
rs760385302 CA9362094 |
230 | T>R | No |
ClinGen ExAC gnomAD |
|
|
CA9362096 rs572771067 |
234 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9362097 rs572771067 |
234 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1313922721 CA405211280 |
235 | S>L | No |
ClinGen gnomAD |
|
|
rs1315930267 CA405211317 |
238 | F>L | No |
ClinGen gnomAD |
|
|
rs751612872 CA9362099 |
239 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA405211339 rs1226245973 |
239 | D>H | No |
ClinGen gnomAD |
|
|
CA405211362 rs1202491497 |
240 | P>H | No |
ClinGen gnomAD |
|
|
CA9362103 rs770070086 |
241 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA307539995 rs929201472 |
241 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs770070086 CA9362104 |
241 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405211382 rs1483240756 |
243 | Q>* | No |
ClinGen TOPMed |
|
|
rs1472378586 CA405211417 |
245 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA405211436 rs1157302011 |
246 | A>V | No |
ClinGen gnomAD |
|
|
rs946383536 CA307539996 |
250 | L>S | No |
ClinGen gnomAD |
|
|
rs1044827821 CA307539997 |
252 | R>G | No |
ClinGen Ensembl |
|
|
rs774053759 CA9362107 |
253 | C>S | No |
ClinGen ExAC gnomAD |
|
|
CA307539998 rs140728940 |
253 | C>Y | No |
ClinGen 1000Genomes |
|
|
rs1048996124 CA307539999 |
254 | I>N | No |
ClinGen TOPMed |
|
|
CA405211567 rs1450864450 |
255 | K>N | No |
ClinGen gnomAD |
|
|
CA9362108 rs761395193 |
257 | W>G | No |
ClinGen ExAC gnomAD |
|
|
rs1350318862 CA405211616 |
258 | D>V | No |
ClinGen gnomAD |
|
|
rs771826170 CA9362109 |
260 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA307540001 rs773154150 |
260 | T>I | No |
ClinGen Ensembl |
|
|
rs777838329 CA307540002 |
261 | S>P | No |
ClinGen Ensembl |
|
|
CA307540004 rs879045054 |
262 | Q>H | No |
ClinGen Ensembl |
|
|
rs377500931 CA9362110 |
262 | Q>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA405211683 rs1313236012 |
262 | Q>L | No |
ClinGen TOPMed |
|
|
rs1313858280 CA405211692 |
263 | A>S | No |
ClinGen gnomAD |
|
|
rs760323135 CA9362111 |
263 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA9362113 rs753595272 |
264 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759519170 CA9362114 |
264 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405211754 rs1172039021 |
267 | T>I | No |
ClinGen gnomAD |
|
| TCGA novel | 269 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405211788 rs1568364873 |
269 | T>I | No |
ClinGen Ensembl |
|
|
rs1230580877 CA405212687 |
270 | K>N | No |
ClinGen gnomAD |
|
|
CA9362132 rs764944367 |
271 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA405212695 rs1355465499 |
272 | H>Y | No |
ClinGen gnomAD |
|
|
rs1207849205 CA405212706 |
273 | S>C | No |
ClinGen gnomAD |
|
|
CA405212711 rs1287925072 |
274 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1222353701 CA405212751 |
280 | C>R | No |
ClinGen gnomAD |
|
|
CA9362134 rs762900723 |
282 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA9362135 rs767526630 |
284 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1472639742 CA405212784 |
284 | S>R | No |
ClinGen gnomAD |
|
|
CA405212782 rs1391329076 |
284 | S>T | No |
ClinGen gnomAD |
|
|
rs148143446 CA9362136 |
287 | F>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA405212813 rs1415458334 |
289 | C>R | No |
ClinGen gnomAD |
|
|
rs1323534877 CA405212815 |
289 | C>Y | No |
ClinGen TOPMed |
|
|
rs756339559 CA9362137 |
291 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA9362138 rs766698986 |
293 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs1454699628 CA405212844 |
293 | W>* | No |
ClinGen gnomAD |
|
| TCGA novel | 295 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1036131338 CA307540543 |
297 | L>* | No |
ClinGen Ensembl |
|
|
CA9362140 rs755400871 |
298 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs779365427 CA9362141 |
299 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs758903617 CA9362143 |
302 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA405212913 rs1358705585 |
303 | H>Y | No |
ClinGen gnomAD |
|
|
rs1171658458 CA405212921 |
304 | T>A | No |
ClinGen TOPMed |
|
|
CA307540544 rs201210259 CA307540545 |
305 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA405212926 rs201210259 |
305 | G>W | No |
ClinGen TOPMed gnomAD |
|
|
rs1193023525 CA405212942 |
307 | F>C | No |
ClinGen TOPMed |
|
|
CA9362146 COSM994682 rs746514517 |
308 | R>* | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA9362147 rs770635793 |
308 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
VAR_032030 CA9362148 rs11881580 |
310 | C>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA9362149 rs745463721 |
310 | C>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 312 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405212973 rs1458869710 |
312 | A>V | No |
ClinGen TOPMed |
|
|
CA9362151 rs775316893 |
313 | C>* | No |
ClinGen ExAC gnomAD |
|
|
CA405212985 rs1158050446 |
314 | V>E | No |
ClinGen gnomAD |
|
|
rs930942136 CA307540546 |
319 | G>A | No |
ClinGen TOPMed gnomAD |
|
|
rs571091956 CA9362153 |
320 | H>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs571091956 CA9362154 |
320 | H>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs760808538 CA9362155 |
322 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA307540547 rs938493076 |
322 | G>S | No |
ClinGen gnomAD |
|
|
CA9362156 rs760808538 |
322 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779946826 CA9362157 |
326 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs1340910043 CA405213060 |
326 | S>P | No |
ClinGen gnomAD |
|
|
CA307540548 rs916309262 |
327 | C>G | No |
ClinGen TOPMed |
|
|
rs765733742 CA405213090 |
330 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs1327366823 CA405213087 |
330 | A>T | No |
ClinGen gnomAD |
|
|
rs765733742 CA9362159 |
330 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs765538459 CA307540974 |
334 | S>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765538459 CA9362176 |
334 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs138717522 CA307540976 |
339 | G>E | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs753069912 CA9362177 |
339 | G>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 340 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9362179 rs764306322 |
343 | R>T | No |
ClinGen ExAC gnomAD |
|
|
rs1395568192 CA405213780 |
346 | A>T | No |
ClinGen gnomAD |
|
|
rs752127991 CA9362180 |
346 | A>V | No |
ClinGen ExAC |
|
|
CA307540981 rs200178208 |
348 | W>L | No |
ClinGen Ensembl |
|
|
rs1166461189 CA405213879 |
353 | G>S | No |
ClinGen gnomAD |
|
|
rs1346383343 CA405213890 |
354 | Y>C | No |
ClinGen TOPMed |
|
|
rs150713418 CA9362183 |
355 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs142717725 CA9362182 |
355 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9362184 rs368108396 |
356 | K>N | No |
ClinGen ESP ExAC gnomAD |
|
|
CA9362185 rs779756076 |
358 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA405213923 rs1372328636 |
360 | K>E | No |
ClinGen gnomAD |
|
| TCGA novel | 361 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1213339071 CA405214201 |
362 | H>R | No |
ClinGen TOPMed |
|
|
CA307542494 rs994716918 |
365 | W>* | No |
ClinGen TOPMed |
|
|
CA405214280 rs1249763471 |
367 | M>I | No |
ClinGen gnomAD |
|
|
CA9362207 rs142169288 |
368 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs778814914 CA9362208 |
369 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs11668547 CA307542514 |
372 | S>I | No |
ClinGen Ensembl |
|
|
CA9362211 rs1981827 |
374 | N>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA405214384 rs1358501274 |
375 | K>E | No |
ClinGen gnomAD |
|
|
CA9362212 rs149540278 |
375 | K>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9362213 rs746885751 |
376 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs1456726393 CA405214418 COSM1712130 |
377 | W>* | skin [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA307542564 rs956691814 |
378 | I>S | No |
ClinGen Ensembl |
|
|
CA9362214 rs144099790 |
378 | I>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA405214457 rs892255611 |
380 | S>C | No |
ClinGen TOPMed gnomAD |
|
|
CA307542573 rs892255611 |
380 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
rs775390989 CA9362215 |
380 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs1302622164 CA405214465 |
381 | A>S | No |
ClinGen gnomAD |
|
|
rs768741120 CA9362217 |
383 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs752419607 CA9362245 |
384 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA9362244 rs764781611 |
384 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs764019263 CA405215636 |
385 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757278706 CA9362249 |
386 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9362248 rs751290834 |
386 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA405215648 CA9362250 rs200368986 |
387 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA307548210 rs993894810 |
387 | M>T | No |
ClinGen gnomAD |
|
| TCGA novel | 387 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405215651 rs1321284002 |
388 | R>K | No |
ClinGen TOPMed |
|
|
rs750309839 CA9362251 |
389 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs755030166 COSM710387 CA9362252 |
390 | W>C | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA405215661 rs1291251743 |
390 | W>R | No |
ClinGen TOPMed gnomAD |
|
|
rs778920204 CA9362253 |
391 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA405215692 rs1382005846 COSM1392657 |
394 | E>* | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
| TCGA novel | 394 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9362255 rs772254326 |
395 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1339885621 CA405215702 |
395 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1568373065 CA405215705 |
396 | D>H | No |
ClinGen Ensembl |
|
| TCGA novel | 399 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs143369467 CA9362257 |
408 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs777013462 CA9362259 |
409 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 409 | G>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405215817 rs1297537549 |
412 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs530876000 CA9362260 |
412 | L>W | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA307548253 rs543510035 |
413 | K>* | No |
ClinGen TOPMed |
|
|
rs753214293 CA9362287 |
415 | C>* | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs753214293 | 415 | C>= | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761481837 CA9362284 |
415 | C>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9362285 rs753214293 |
415 | C>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs116680138 CA9362288 |
416 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs753706528 CA405216982 |
417 | R>I | No |
ClinGen ExAC gnomAD |
|
|
rs753706528 CA9362290 |
417 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA9362289 rs753706528 |
417 | R>T | No |
ClinGen ExAC gnomAD |
|
|
CA9362291 rs764181250 |
418 | C>F | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 419 | D>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1471559247 CA405217043 |
420 | R>T | No |
ClinGen TOPMed |
|
|
CA9362292 rs751759441 |
421 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1334129164 CA405217218 |
429 | T>A | No |
ClinGen gnomAD |
|
|
CA405217226 rs77589178 |
429 | T>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs77589178 CA9362297 |
429 | T>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9362300 rs773875375 |
431 | S>F | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 432 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9362303 rs539358526 |
433 | M>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9362302 rs570267559 |
433 | M>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs571512176 CA307551651 |
436 | Q>R | No |
ClinGen Ensembl |
|
|
CA9362304 rs760463708 |
437 | C>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs556151988 CA9362305 COSM994685 |
438 | V>M | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA9362306 rs142286952 |
440 | C>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA405217399 rs1293226153 |
440 | C>W | No |
ClinGen TOPMed |
|
|
CA405217404 rs575618079 |
441 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9362307 rs575618079 |
441 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA307551660 rs370633263 |
441 | R>W | No |
ClinGen ESP TOPMed |
|
|
rs151252826 CA9362308 |
443 | D>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA405217434 rs1395389291 |
444 | T>I | No |
ClinGen gnomAD |
|
|
CA405217437 rs1395389291 |
444 | T>K | No |
ClinGen gnomAD |
|
|
CA9362311 rs757478322 |
445 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs868518012 CA307551688 |
445 | R>K | No |
ClinGen Ensembl |
|
|
CA307551738 rs756563131 |
446 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405217454 rs1346056489 |
446 | G>D | No |
ClinGen TOPMed |
|
|
CA9362313 rs756563131 |
446 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs187257808 CA9362314 |
448 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 449 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1331056394 CA405217484 |
449 | A>V | No |
ClinGen gnomAD |
|
|
rs749847465 CA9362315 |
451 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9362316 rs749847465 |
451 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405217528 rs1168016306 |
453 | S>L | No |
ClinGen TOPMed |
|
|
CA9362320 rs747684854 |
455 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs1228105144 CA405217549 |
455 | S>P | No |
ClinGen gnomAD |
|
|
rs1228105144 CA405217547 |
455 | S>T | No |
ClinGen gnomAD |
|
|
rs771413024 CA9362321 |
457 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA9362322 rs777412006 |
458 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777412006 CA9362323 |
458 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs776378566 CA9362325 |
461 | E>G | No |
ClinGen ExAC |
|
|
rs1161235853 CA405217616 |
461 | E>K | No |
ClinGen gnomAD |
|
|
rs142578978 CA9362327 |
464 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1168022151 CA405217676 |
465 | P>Q | No |
ClinGen gnomAD |
|
|
CA9362330 rs761958145 |
467 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9362329 rs761958145 |
467 | R>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs900945130 CA307551871 |
469 | S>G | No |
ClinGen TOPMed |
|
|
rs895606290 CA307551872 |
469 | S>I | No |
ClinGen Ensembl |
|
|
rs760940871 CA9362332 |
473 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs760940871 CA9362333 |
473 | D>R | No |
ClinGen ExAC gnomAD |
|
|
CA9362334 rs146733199 |
473 | D>W | No |
ClinGen ESP ExAC |
No associated diseases with Q6ZMY6
13 regional properties for Q6ZMY6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 91 - 215 | IPR001680-1 |
| repeat | WD40 repeat | 218 - 310 | IPR001680-2 |
| repeat | WD40 repeat | 310 - 400 | IPR001680-3 |
| repeat | Pyrrolo-quinoline quinone repeat | 160 - 190 | IPR002372 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 152 - 184 | IPR018391 |
| conserved_site | WD40 repeat, conserved site | 160 - 174 | IPR019775-1 |
| conserved_site | WD40 repeat, conserved site | 245 - 259 | IPR019775-2 |
| conserved_site | WD40 repeat, conserved site | 288 - 302 | IPR019775-3 |
| conserved_site | WD40 repeat, conserved site | 336 - 350 | IPR019775-4 |
| conserved_site | WD40 repeat, conserved site | 378 - 392 | IPR019775-5 |
| repeat | G-protein beta WD-40 repeat | 117 - 131 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 336 - 350 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 378 - 392 | IPR020472-3 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q0V8J1 | WSB2 | WD repeat and SOCS box-containing protein 2 | Bos taurus (Bovine) | PR |
| Q8N157 | AHI1 | Jouberin | Homo sapiens (Human) | PR |
| Q9NYS7 | WSB2 | WD repeat and SOCS box-containing protein 2 | Homo sapiens (Human) | PR |
| Q8TEB1 | DCAF11 | DDB1- and CUL4-associated factor 11 | Homo sapiens (Human) | PR |
| Q5F201 | Cfap52 | Cilia- and flagella-associated protein 52 | Mus musculus (Mouse) | PR |
| O54929 | Wsb2 | WD repeat and SOCS box-containing protein 2 | Mus musculus (Mouse) | PR |
| Q8K3E5 | Ahi1 | Jouberin | Mus musculus (Mouse) | PR |
| A6H603 | Nwd1 | NACHT domain- and WD repeat-containing protein 1 | Mus musculus (Mouse) | PR |
| Q23256 | wdr-5.3 | WD repeat-containing protein wdr-5.3 | Caenorhabditis elegans | PR |
| Q94AI7 | TPL | Protein TOPLESS | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0WV90 | TPR1 | Topless-related protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRZ0 | TPR2 | Topless-related protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASPPRCSPT | AHDRECKLPP | PSAPASEYCP | GKLSWGTMAR | ALGRFKLSIP | HTHLLATLDP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LALDREPPPH | LLPEKHQVPE | KLIWGDQDPL | SKIPFKILSG | HEHAVSTCHF | CVDDTKLLSG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SYDCTVKLWD | PVDGSVVRDF | EHRPKAPVVE | CSITGDSSRV | IAASYDKTVR | AWDLETGKLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WKVRYDTFIV | SCKFSPDGKY | VVSGFDVDHG | ICIMDAENIT | TVSVIKDHHT | RSITSCCFDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DSQRVASVSL | DRCIKIWDVT | SQATLLTITK | AHSNAISNCC | FTFSGHFLCT | SSWDKNLKIW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NVHTGEFRNC | GACVTLMQGH | EGSVSSCHFA | RDSSFLISGG | FDRTVAIWDV | AEGYRKLSLK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GHNDWVMDVA | ISNNKKWILS | ASKDRTMRLW | NIEEIDEIPL | VIKYKKAVGL | KLKQCERCDR |
| 430 | 440 | 450 | 460 | 470 | |
| PFSIFKSDTS | SEMFTQCVFC | RIDTRGLPAD | TSSSSSSSER | ENSPPPRGSK | DD |