Q0V8J1
Gene name |
WSB2 |
Protein name |
WD repeat and SOCS box-containing protein 2 |
Names |
WSB-2 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:508388 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0V8J1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0V8J1-F1 | Predicted | AlphaFoldDB |
No variants for Q0V8J1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0V8J1 | |||||
No associated diseases with Q0V8J1
8 regional properties for Q0V8J1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SOCS box domain | 362 - 406 | IPR001496 |
| repeat | WD40 repeat | 83 - 186 | IPR001680-1 |
| repeat | WD40 repeat | 188 - 325 | IPR001680-2 |
| repeat | WD40 repeat | 326 - 363 | IPR001680-3 |
| conserved_site | WD40 repeat, conserved site | 171 - 185 | IPR019775 |
| repeat | G-protein beta WD-40 repeat | 128 - 142 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 171 - 185 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 256 - 270 | IPR020472-3 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular signal transduction | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. |
| protein polyubiquitination | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q6ZMY6 | WDR88 | WD repeat-containing protein 88 | Homo sapiens (Human) | PR |
| Q8N157 | AHI1 | Jouberin | Homo sapiens (Human) | PR |
| Q8TEB1 | DCAF11 | DDB1- and CUL4-associated factor 11 | Homo sapiens (Human) | PR |
| Q9NYS7 | WSB2 | WD repeat and SOCS box-containing protein 2 | Homo sapiens (Human) | PR |
| Q5F201 | Cfap52 | Cilia- and flagella-associated protein 52 | Mus musculus (Mouse) | PR |
| Q8K3E5 | Ahi1 | Jouberin | Mus musculus (Mouse) | PR |
| A6H603 | Nwd1 | NACHT domain- and WD repeat-containing protein 1 | Mus musculus (Mouse) | PR |
| O54929 | Wsb2 | WD repeat and SOCS box-containing protein 2 | Mus musculus (Mouse) | PR |
| Q23256 | wdr-5.3 | WD repeat-containing protein wdr-5.3 | Caenorhabditis elegans | PR |
| Q94AI7 | TPL | Protein TOPLESS | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0WV90 | TPR1 | Topless-related protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRZ0 | TPR2 | Topless-related protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLSPAPEEPL | LLAELKPGRP | HQFDWKSSCE | TWSVAFSPDG | SWFAWSQGHC | IVKLIPWPLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EQFIPKGFEA | KSRSSKNETK | GRGSPKEKTL | DCGQIVWGLA | FSPWPSPPSK | KLWARHHPQV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PDVSCLILAT | GLNDGQIKIW | EVQTGLLLLN | LSGHQDVVRD | LSFTPSGSLI | LVSASRDKTL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RIWDLNKHGK | QIQVLSGHLQ | WVYCCSISPD | CSMLCSAAGE | KSVFLWSMRS | YTLIRKLEGH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QSSVVSCDFS | PDSALLVTAS | YDTNVIMWDP | YTGERLRSLH | HTQLNPPMDD | SDVHISSLRS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VCFSPEGLYL | ATVADDRLLR | IWALELKTPI | AFAPMTNGLC | CTFFPHGGVI | ATGTRDGHVQ |
| 370 | 380 | 390 | 400 | ||
| FWTAPRVLSS | LKHLCRKALR | SFLTTYQVLA | LPIPKKMKEF | LTYRTF |