Q23256
Gene name |
wdr-5.3 (swd-3.3, ZC302.2) |
Protein name |
WD repeat-containing protein wdr-5.3 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_ZC302.2 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q23256
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q23256-F1 | Predicted | AlphaFoldDB |
No variants for Q23256
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q23256 | |||||
No associated diseases with Q23256
6 regional properties for Q23256
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 202 - 499 | IPR001680 |
| conserved_site | WD40 repeat, conserved site | 312 - 326 | IPR019775-1 |
| conserved_site | WD40 repeat, conserved site | 354 - 368 | IPR019775-2 |
| repeat | G-protein beta WD-40 repeat | 228 - 242 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 312 - 326 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 442 - 456 | IPR020472-3 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| MLL3/4 complex | A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q0V8J1 | WSB2 | WD repeat and SOCS box-containing protein 2 | Bos taurus (Bovine) | PR |
| Q6ZMY6 | WDR88 | WD repeat-containing protein 88 | Homo sapiens (Human) | PR |
| Q8N157 | AHI1 | Jouberin | Homo sapiens (Human) | PR |
| Q9NYS7 | WSB2 | WD repeat and SOCS box-containing protein 2 | Homo sapiens (Human) | PR |
| Q8TEB1 | DCAF11 | DDB1- and CUL4-associated factor 11 | Homo sapiens (Human) | PR |
| Q5F201 | Cfap52 | Cilia- and flagella-associated protein 52 | Mus musculus (Mouse) | PR |
| O54929 | Wsb2 | WD repeat and SOCS box-containing protein 2 | Mus musculus (Mouse) | PR |
| Q8K3E5 | Ahi1 | Jouberin | Mus musculus (Mouse) | PR |
| A6H603 | Nwd1 | NACHT domain- and WD repeat-containing protein 1 | Mus musculus (Mouse) | PR |
| Q94AI7 | TPL | Protein TOPLESS | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0WV90 | TPR1 | Topless-related protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRZ0 | TPR2 | Topless-related protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNPERQETIS | PKNVPFQPVP | TPNQQSLQSR | MLESNQAVPD | AFQKVAAWNH | YNAVATPPIG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VPQTARPPSN | QSPHPNPPGY | PYQSHQQQFH | PLAIAFQQPF | GLPQQVIYPP | PPPGFTPHRV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QVSPVGLLGP | PGFFPQFAGS | TTSQGNPSEV | SVRTKSAEGT | TGPIAPSITT | KPTSTIQVAP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PRDPVAPTTS | SSGITKKPEN | GEFSLVKTIS | GHTKSVSVIK | FSYCGKYLGT | GSADKQIKVW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NTVDMTYLQT | LASHQLGIND | FSWSSNSQFI | ASASDDTTVK | IFDVISGACL | RTMRGHTNYV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FCCSFNPQSS | LIASAGFDET | VRVWDFKTGL | CVKCIPAHSD | PITSISYNHD | GNTMATSSYD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GCIRVWDAAS | GSCLKTLVDT | DHAPVTFVCF | SPNGKYLLSA | QLDSSLKLWD | PKKAKPLKYY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NGHKNKKYCL | FANMSVPLGK | HIISGSEDGR | ILVWSIQTKQ | IVQILEGHTT | PVLATDSHPT |
| 490 | 500 | ||||
| LNIIASGGLE | PDNVIRIWRR | N |