Q60900
Gene name |
Elavl3 (Huc) |
Protein name |
ELAV-like protein 3 |
Names |
Hu-antigen C, HuC |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:15571 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
4 structures for Q60900
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1D8Z | NMR | - | A | 36-123 | PDB |
| 1D9A | NMR | - | A | 124-208 | PDB |
| 1FNX | NMR | - | H | 36-208 | PDB |
| AF-Q60900-F1 | Predicted | AlphaFoldDB |
12 variants for Q60900
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs1134083846 | 45 | Y>C | No | EVA | |
| rs3389036712 | 60 | G>V | No | EVA | |
| rs3389030369 | 61 | S>R | No | EVA | |
| rs3389009731 | 67 | S>T | No | EVA | |
| rs3389004335 | 86 | N>K | No | EVA | |
| rs3389028072 | 116 | R>H | No | EVA | |
| rs3389030242 | 122 | I>N | No | EVA | |
| rs3389028043 | 165 | S>T | No | EVA | |
| rs3389024030 | 175 | K>N | No | EVA | |
| rs3389030206 | 267 | M>K | No | EVA | |
| rs3389004352 | 296 | D>N | No | EVA | |
| rs49423886 | 332 | M>I | No | EVA |
No associated diseases with Q60900
No regional properties for Q60900
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q60900 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA 3'-UTR AU-rich region binding | Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P26378 | ELAVL4 | ELAV-like protein 4 | Homo sapiens (Human) | PR |
| Q12926 | ELAVL2 | ELAV-like protein 2 | Homo sapiens (Human) | PR |
| Q14576 | ELAVL3 | ELAV-like protein 3 | Homo sapiens (Human) | PR |
| Q7TPD6 | Raver2 | Ribonucleoprotein PTB-binding 2 | Mus musculus (Mouse) | PR |
| Q61701 | Elavl4 | ELAV-like protein 4 | Mus musculus (Mouse) | PR |
| Q60899 | Elavl2 | ELAV-like protein 2 | Mus musculus (Mouse) | PR |
| Q9Z1D1 | Eif3g | Eukaryotic translation initiation factor 3 subunit G | Mus musculus (Mouse) | PR |
| Q8CH84 | Elavl2 | ELAV-like protein 2 | Rattus norvegicus (Rat) | PR |
| O09032 | Elavl4 | ELAV-like protein 4 | Rattus norvegicus (Rat) | PR |
| Q28GD4 | elavl2 | ELAV-like protein 2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A4QNI8 | elavl4 | ELAV-like protein 4 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q28FX0 | elavl3 | ELAV-like protein 3 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVTQILGAME | SQVGGGPAGP | ALPNGPLLGT | NGATDDSKTN | LIVNYLPQNM | TQDEFKSLFG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SIGDIESCKL | VRDKITGQSL | GYGFVNYSDP | NDADKAINTL | NGLKLQTKTI | KVSYARPSSA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SIRDANLYVS | GLPKTMSQKE | MEQLFSQYGR | IITSRILLDQ | ATGVSRGVGF | IRFDKRIEAE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EAIKGLNGQK | PLGAAEPITV | KFANNPSQKT | GQALLTHLYQ | SSARRYAGPL | HHQTQRFRLD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NLLNMAYGVK | SPLSLIARFS | PIAIDGMSGL | AGVGLSGGAA | GAGWCIFVYN | LSPEADESVL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WQLFGPFGAV | TNVKVIRDFT | TNKCKGFGFV | TMTNYDEAAM | AIASLNGYRL | GERVLQVSFK |
| TSKQHKA |