Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8CH84
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8CH84-F1 | Predicted | AlphaFoldDB |
No variants for Q8CH84
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8CH84 | |||||
No associated diseases with Q8CH84
7 regional properties for Q8CH84
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GAF domain | 158 - 317 | IPR003018 |
| domain | Histidine kinase/HSP90-like ATPase | 455 - 587 | IPR003594 |
| domain | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain | 341 - 408 | IPR003661 |
| domain | Signal transduction histidine kinase-related protein, C-terminal | 511 - 525 | IPR004358-1 |
| domain | Signal transduction histidine kinase-related protein, C-terminal | 529 - 539 | IPR004358-2 |
| domain | Signal transduction histidine kinase-related protein, C-terminal | 546 - 564 | IPR004358-3 |
| domain | Histidine kinase domain | 350 - 587 | IPR005467 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| synapse | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to leukemia inhibitory factor | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P26378 | ELAVL4 | ELAV-like protein 4 | Homo sapiens (Human) | PR |
| Q14576 | ELAVL3 | ELAV-like protein 3 | Homo sapiens (Human) | PR |
| Q12926 | ELAVL2 | ELAV-like protein 2 | Homo sapiens (Human) | PR |
| Q60900 | Elavl3 | ELAV-like protein 3 | Mus musculus (Mouse) | PR |
| Q7TPD6 | Raver2 | Ribonucleoprotein PTB-binding 2 | Mus musculus (Mouse) | PR |
| Q61701 | Elavl4 | ELAV-like protein 4 | Mus musculus (Mouse) | PR |
| Q60899 | Elavl2 | ELAV-like protein 2 | Mus musculus (Mouse) | PR |
| Q5RK09 | Eif3g | Eukaryotic translation initiation factor 3 subunit G | Rattus norvegicus (Rat) | PR |
| O09032 | Elavl4 | ELAV-like protein 4 | Rattus norvegicus (Rat) | PR |
| A4QNI8 | elavl4 | ELAV-like protein 4 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q28FX0 | elavl3 | ELAV-like protein 3 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q28GD4 | elavl2 | ELAV-like protein 2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| METQLSNGPT | CNNTANGPTT | VNNNCSSPVD | SGNTEDSKTN | LIDNYLPQNM | TQEELKSLFG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SIGEIESCKL | VRDKITGQSL | GYGFVNYIDP | KDAEKAINTL | NGLRLQTKTI | KVSYARPSSA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SIRDANLYVS | GLPKTMTQKE | LEQLFSQYGR | IITSRILVDQ | VTGISRGVGF | IRFDKRIEAE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EAIKGLNGQK | PPGATEPITV | KFANNPSQKT | NQAILSQLYQ | SPNRRYPGPL | AQQAQRFRLD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NLLNMAYGVK | RFSPMTIDGM | TSLAGINIPG | HPGTGWCIFV | YNLAPDADES | ILWQMFGPFG |
| 310 | 320 | 330 | 340 | 350 | |
| AVTNVKVIRD | FNTNKCKGFG | FVTMTNYDEA | AMAIASLNGY | RLGDRVLQVS | FKTNKTHKA |