Q28FX0

PR
Gene name
elavl3
Protein name
ELAV-like protein 3
Names
Protein ElrC
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:594912
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q28FX0

Entry ID Method Resolution Chain Position Source
AF-Q28FX0-F1 Predicted AlphaFoldDB

No variants for Q28FX0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q28FX0

No associated diseases with Q28FX0

11 regional properties for Q28FX0

Type Name Position InterPro Accession
domain FERM domain 211 - 492 IPR000299
domain SAB domain 661 - 709 IPR007477
domain Band 4.1, C-terminal 747 - 854 IPR008379
domain FERM adjacent 499 - 545 IPR014847
domain FERM, N-terminal 215 - 277 IPR018979
domain FERM, C-terminal PH-like domain 406 - 496 IPR018980
conserved_site FERM conserved site 265 - 293 IPR019747-1
conserved_site FERM conserved site 372 - 401 IPR019747-2
domain FERM central domain 295 - 402 IPR019748
domain Band 4.1 domain 207 - 402 IPR019749
domain Band 4.1 protein, FERM domain, F1 sub-domain 211 - 293 IPR021187

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
nervous system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P26378 ELAVL4 ELAV-like protein 4 Homo sapiens (Human) PR
Q12926 ELAVL2 ELAV-like protein 2 Homo sapiens (Human) PR
Q14576 ELAVL3 ELAV-like protein 3 Homo sapiens (Human) PR
Q7TPD6 Raver2 Ribonucleoprotein PTB-binding 2 Mus musculus (Mouse) PR
Q60899 Elavl2 ELAV-like protein 2 Mus musculus (Mouse) PR
Q61701 Elavl4 ELAV-like protein 4 Mus musculus (Mouse) PR
Q60900 Elavl3 ELAV-like protein 3 Mus musculus (Mouse) PR
Q8CH84 Elavl2 ELAV-like protein 2 Rattus norvegicus (Rat) PR
O09032 Elavl4 ELAV-like protein 4 Rattus norvegicus (Rat) PR
A4QNI8 elavl4 ELAV-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q28GD4 elavl2 ELAV-like protein 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q28CY2 eif3g Eukaryotic translation initiation factor 3 subunit G Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MVTQIISTME TQASNGPGSV GILNGTNGAA DDSKTNLIVN YLPQNMTQEE FKSLFGSIGE
70 80 90 100 110 120
IESCKLVRDK ITGQSLGYGF VNYVDPNDAD KAINTLNGLK LQTKTIKVSY ARPSSASIRD
130 140 150 160 170 180
ANLYVSSLPK TMNQKEMEQL FSQYGRIITS RILVDQVTGS VSRGVGFIRF DKRIEAEEAI
190 200 210 220 230 240
KGLNGQKPLG ASEPITVKFA NNPSQKTGQA LLTHLYQTTA RRYTGPLHHQ TQRFRFSPIT
250 260 270 280 290 300
IDSVTNLAGV SLTGPTTAGW CIFVYNLSPE ADESVLWQLF GPFGAVTNVK VIRDFTTNKC
310 320 330 340
KGFGFVTMTN YDEAAMAIAS LNGYRLGDRV LQVSFKTSKQ HKA