Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q28GD4

Entry ID Method Resolution Chain Position Source
AF-Q28GD4-F1 Predicted AlphaFoldDB

No variants for Q28GD4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q28GD4

No associated diseases with Q28GD4

5 regional properties for Q28GD4

Type Name Position InterPro Accession
domain RNA recognition motif domain 67 - 145 IPR000504-1
domain RNA recognition motif domain 153 - 233 IPR000504-2
domain RNA recognition motif domain 292 - 370 IPR000504-3
domain HuB, RNA recognition motif 3 289 - 374 IPR034914
domain HuB, RNA recognition motif 2 148 - 231 IPR034999

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasm, cell cortex
  • Enriched at the vegetal cortex in stage III and IV oocytes
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell cortex The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P26378 ELAVL4 ELAV-like protein 4 Homo sapiens (Human) PR
Q14576 ELAVL3 ELAV-like protein 3 Homo sapiens (Human) PR
Q12926 ELAVL2 ELAV-like protein 2 Homo sapiens (Human) PR
Q60900 Elavl3 ELAV-like protein 3 Mus musculus (Mouse) PR
Q7TPD6 Raver2 Ribonucleoprotein PTB-binding 2 Mus musculus (Mouse) PR
Q61701 Elavl4 ELAV-like protein 4 Mus musculus (Mouse) PR
Q60899 Elavl2 ELAV-like protein 2 Mus musculus (Mouse) PR
O09032 Elavl4 ELAV-like protein 4 Rattus norvegicus (Rat) PR
Q8CH84 Elavl2 ELAV-like protein 2 Rattus norvegicus (Rat) PR
Q28FX0 elavl3 ELAV-like protein 3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
A4QNI8 elavl4 ELAV-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q28CY2 eif3g Eukaryotic translation initiation factor 3 subunit G Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MAVRLCDVAS LLRSGSWAAE PWTGQVIAAM ETQLSNGPTC NNTANCPNTI NNCSSPVESS
70 80 90 100 110 120
NTEDSKTNLI VNYLPQNMTQ EELKSLFGSI GEIESCKLVR DKITGQSLGY GFVNYIDPKD
130 140 150 160 170 180
AEKAINTLNG LRLQTKTIKV SYARPSSASI RDANLYVSGL PKTMTQKELE QLFSQYGRII
190 200 210 220 230 240
TSRILVDQVT GVSRGVGFIR FDKRIEAEEA IKGLNGQKPP GATEPITVKF ANNPSQKVNH
250 260 270 280 290 300
TILSQLYQSP NRRYPGPLAQ QAQRFSRFSP MTIDGMTSLA GINFPGHAGT GWCIFVYNLA
310 320 330 340 350 360
PDADESILWQ MFGPFGAVTN VKVIRDFNTN KCKGFGFVTM TNYDEAAMAI ASLNGYRLGD
370
RVLQVSFKTS KTHKA