Q5RJS6
Gene name |
Mospd1 |
Protein name |
Motile sperm domain-containing protein 1 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:686087 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RJS6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RJS6-F1 | Predicted | AlphaFoldDB |
No variants for Q5RJS6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RJS6 | |||||
No associated diseases with Q5RJS6
1 regional properties for Q5RJS6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major sperm protein (MSP) domain | 16 - 143 | IPR000535 |
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A2VDZ9 | VAPB | Vesicle-associated membrane protein-associated protein B | Bos taurus (Bovine) | PR |
| Q2T9W7 | MOSPD1 | Motile sperm domain-containing protein 1 | Bos taurus (Bovine) | PR |
| O95292 | VAPB | Vesicle-associated membrane protein-associated protein B/C | Homo sapiens (Human) | PR |
| Q9QY76 | Vapb | Vesicle-associated membrane protein-associated protein B | Mus musculus (Mouse) | PR |
| Q8VEL0 | Mospd1 | Motile sperm domain-containing protein 1 | Mus musculus (Mouse) | PR |
| Q9Z269 | Vapb | Vesicle-associated membrane protein-associated protein B | Rattus norvegicus (Rat) | PR |
| Q5RJS6 | Mospd1 | Motile sperm domain-containing protein 1 | Rattus norvegicus (Rat) | PR |
| Q8VZ95 | PVA11 | Vesicle-associated protein 1-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LPQ7 | PVA43 | Vesicle-associated protein 4-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VYN2 | PVA42 | Vesicle-associated protein 4-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q1ECE0 | PVA41 | Vesicle-associated protein 4-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHQQKRQPEL | VEGNLPVFVF | PTELIFYADD | QSTHKQVLTL | YNPYEFALKF | KVLCTTPNKY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VVIDAAGAVK | PQCCVDIVIR | HRDVRSCHYG | VIDKFRLQVS | EQSQRKALGR | KEVIATLLPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AKEQQKEEEE | KRIKEHLTES | VFFEQSCQPE | NRAVSSGPSL | LTVFLGVVCI | AALMLPTLGD |
| 190 | 200 | 210 | |||
| MESLVPLYLH | LSVNQKLVAA | YILGLITMAI | LRT |