Q2T9W7
Gene name |
MOSPD1 |
Protein name |
Motile sperm domain-containing protein 1 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:523578 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2T9W7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2T9W7-F1 | Predicted | AlphaFoldDB |
44 variants for Q2T9W7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs438602626 | 29 | D>A | No | EVA | |
| rs456244833 | 36 | Q>* | No | EVA | |
| rs443750800 | 37 | V>A | No | EVA | |
| rs476503165 | 43 | P>A | No | EVA | |
| rs454823888 | 44 | Y>D | No | EVA | |
| rs472715028 | 47 | A>D | No | EVA | |
| rs436302437 | 47 | A>T | No | EVA | |
| rs454374761 | 49 | K>R | No | EVA | |
| rs432597719 | 50 | F>S | No | EVA | |
| rs461238287 | 55 | T>N | No | EVA | |
| rs476515551 | 55 | T>S | No | EVA | |
| rs442790801 | 59 | K>T | No | EVA | |
| rs454020631 | 69 | V>G | No | EVA | |
| rs432710485 | 71 | P>H | No | EVA | |
| rs472073756 | 73 | C>Y | No | EVA | |
| rs435653903 | 86 | S>C | No | EVA | |
| rs468601299 | 93 | D>H | No | EVA | |
| rs480219051 | 103 | S>G | No | EVA | |
| rs458408396 | 120 | S>Y | No | EVA | |
| rs482198641 | 125 | Q>E | No | EVA | |
| rs441700818 | 126 | K>N | No | EVA | |
| rs463771096 | 126 | K>T | No | EVA | |
| rs480914549 | 128 | E>G | No | EVA | |
| rs480914549 | 128 | E>V | No | EVA | |
| rs459326620 | 132 | R>K | No | EVA | |
| rs440740029 | 135 | E>* | No | EVA | |
| rs452344380 | 136 | H>Q | No | EVA | |
| rs470880889 | 136 | H>Y | No | EVA | |
| rs443419249 | 138 | T>N | No | EVA | |
| rs454708414 | 142 | F>V | No | EVA | |
| rs435717473 | 143 | F>C | No | EVA | |
| rs468664810 | 144 | E>Q | No | EVA | |
| rs471117077 | 152 | R>K | No | EVA | |
| rs458843026 | 154 | V>A | No | EVA | |
| rs472871576 | 169 | C>G | No | EVA | |
| rs437663332 | 170 | I>F | No | EVA | |
| rs432534515 | 172 | A>G | No | EVA | |
| rs456259433 | 180 | D>A | No | EVA | |
| rs469081605 | 180 | D>H | No | EVA | |
| rs437681664 | 181 | V>G | No | EVA | |
| rs445543969 | 183 | S>* | No | EVA | |
| rs466789973 | 196 | K>T | No | EVA | |
| rs477037887 | 197 | L>* | No | EVA | |
| rs477037887 | 197 | L>S | No | EVA |
No associated diseases with Q2T9W7
1 regional properties for Q2T9W7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major sperm protein (MSP) domain | 16 - 143 | IPR000535 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A2VDZ9 | VAPB | Vesicle-associated membrane protein-associated protein B | Bos taurus (Bovine) | PR |
| O95292 | VAPB | Vesicle-associated membrane protein-associated protein B/C | Homo sapiens (Human) | PR |
| Q9QY76 | Vapb | Vesicle-associated membrane protein-associated protein B | Mus musculus (Mouse) | PR |
| Q8VEL0 | Mospd1 | Motile sperm domain-containing protein 1 | Mus musculus (Mouse) | PR |
| Q9Z269 | Vapb | Vesicle-associated membrane protein-associated protein B | Rattus norvegicus (Rat) | PR |
| Q5RJS6 | Mospd1 | Motile sperm domain-containing protein 1 | Rattus norvegicus (Rat) | PR |
| Q8VZ95 | PVA11 | Vesicle-associated protein 1-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LPQ7 | PVA43 | Vesicle-associated protein 4-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VYN2 | PVA42 | Vesicle-associated protein 4-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q1ECE0 | PVA41 | Vesicle-associated protein 4-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHQQKRQPEL | VEGNLPVFVF | PTELIFYADD | QSTHKQVLTL | YNPYEFALKF | KVLCTTPNKY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VVVDAAGAVK | PQCCMDIVIR | HRDVRSCHYG | VIDKFRLQVS | EQSQRKALGR | KEVVATLLPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AKEQQKEEEE | KRIKEHLTES | LFFEQSFQPE | NRTVSSGPSL | LTVFLAVVCI | TALMLPTLGD |
| 190 | 200 | 210 | |||
| VESLVPLYLH | LSVNQKLVAA | YILGLITMAI | FRT |