Q1ECE0
Gene name |
PVA41 (MAMI, At5g54110, MJP23.9) |
Protein name |
Vesicle-associated protein 4-1 |
Names |
Plant VAP homolog 4-1, AtPVA41, Protein MEMBRANE-ASSOCIATED MANNITOL-INDUCED, AtMAMI, VAMP-associated protein 4-1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G54110 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1ECE0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1ECE0-F1 | Predicted | AlphaFoldDB |
22 variants for Q1ECE0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_21958370_C_A | 5 | D>E | No | 1000Genomes | |
| ENSVATH03425483 | 12 | E>K | No | 1000Genomes | |
| tmp_5_21958403_C_G | 16 | N>K | No | 1000Genomes | |
| ENSVATH03425484 | 27 | R>S | No | 1000Genomes | |
| ENSVATH07414525 | 35 | T>K | No | 1000Genomes | |
| ENSVATH07414526 | 36 | Q>E | No | 1000Genomes | |
| ENSVATH00733016 | 39 | N>S | No | 1000Genomes | |
| tmp_5_21958479_T_C | 42 | Y>H | No | 1000Genomes | |
| tmp_5_21958489_G_A | 45 | R>H | No | 1000Genomes | |
| ENSVATH00733017 | 48 | N>H | No | 1000Genomes | |
| ENSVATH03425485 | 60 | P>S | No | 1000Genomes | |
| ENSVATH07414529 | 65 | S>T | No | 1000Genomes | |
| tmp_5_21958573_C_A | 73 | A>D | No | 1000Genomes | |
| ENSVATH14631657 | 88 | P>S | No | 1000Genomes | |
| tmp_5_21958877_C_T | 108 | H>Y | No | 1000Genomes | |
| ENSVATH12752947 | 166 | M>L | No | 1000Genomes | |
| ENSVATH03425505 | 174 | V>I | No | 1000Genomes | |
| ENSVATH00733030 | 203 | R>C | No | 1000Genomes | |
| tmp_5_21960007_G_A | 206 | A>T | No | 1000Genomes | |
| tmp_5_21960191_G_A | 238 | G>R | No | 1000Genomes | |
| ENSVATH03425520 | 258 | Q>L | No | 1000Genomes | |
| tmp_5_21960363_C_G | 266 | S>C | No | 1000Genomes |
No associated diseases with Q1ECE0
1 regional properties for Q1ECE0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major sperm protein (MSP) domain | 76 - 199 | IPR000535 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane. |
| endoplasmic reticulum-plasma membrane tethering | The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers. |
| response to osmotic stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2T9W7 | MOSPD1 | Motile sperm domain-containing protein 1 | Bos taurus (Bovine) | PR |
| A2VDZ9 | VAPB | Vesicle-associated membrane protein-associated protein B | Bos taurus (Bovine) | PR |
| O95292 | VAPB | Vesicle-associated membrane protein-associated protein B/C | Homo sapiens (Human) | PR |
| Q8VEL0 | Mospd1 | Motile sperm domain-containing protein 1 | Mus musculus (Mouse) | PR |
| Q9QY76 | Vapb | Vesicle-associated membrane protein-associated protein B | Mus musculus (Mouse) | PR |
| Q5RJS6 | Mospd1 | Motile sperm domain-containing protein 1 | Rattus norvegicus (Rat) | PR |
| Q9Z269 | Vapb | Vesicle-associated membrane protein-associated protein B | Rattus norvegicus (Rat) | PR |
| Q8LPQ7 | PVA43 | Vesicle-associated protein 4-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VYN2 | PVA42 | Vesicle-associated protein 4-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VZ95 | PVA11 | Vesicle-associated protein 1-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPIGDRQNPS | VEKKKNLFRL | CPFWQRRSTT | SSSSTQNPNQ | NYRSRHGNRN | TDISAVSKPP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LTMSSVARSL | LPARRRLRLD | PSSYLYFPYE | PGKQVRSAIK | LKNTSKSHTA | FKFQTTAPKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CYMRPPGGVL | APGESVFATV | FKFVEHPENN | EKQPLNQKSK | VKFKIMSLKV | KPGVEYVPEL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FDEQKDQVAV | EQVLRVIFID | ADRPSAALEK | LKRQLDEAEA | AVEARKKPPP | ETGPRVVGEG |
| 250 | 260 | ||||
| LVIDEWKERR | EKYLARQQVE | SVDSLS |