Q2QN30

PR
Gene name
NRAMP6 (Os12g0581600, LOC_Os12g39180, OsJ_36661)
Protein name
Metal transporter Nramp6
Names
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4352640
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2QN30

Entry ID Method Resolution Chain Position Source
AF-Q2QN30-F1 Predicted AlphaFoldDB

No variants for Q2QN30

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2QN30

No associated diseases with Q2QN30

No regional properties for Q2QN30

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q2QN30

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
cadmium ion transmembrane transporter activity Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.
manganese ion transmembrane transporter activity Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q27981 SLC11A1 Natural resistance-associated macrophage protein 1 Bos taurus (Bovine) PR
P49279 SLC11A1 Natural resistance-associated macrophage protein 1 Homo sapiens (Human) PR
P49281 SLC11A2 Natural resistance-associated macrophage protein 2 Homo sapiens (Human) PR
P41251 Slc11a1 Natural resistance-associated macrophage protein 1 Mus musculus (Mouse) PR
P49282 Slc11a2 Natural resistance-associated macrophage protein 2 Mus musculus (Mouse) PR
O77741 SLC11A1 Natural resistance-associated macrophage protein 1 Sus scrofa (Pig) PR
P70553 Slc11a1 Natural resistance-associated macrophage protein 1 Rattus norvegicus (Rat) PR
O54902 Slc11a2 Natural resistance-associated macrophage protein 2 Rattus norvegicus (Rat) PR
Q6ZG85 NRAT1 Metal transporter NRAT1 Oryza sativa subsp japonica (Rice) PR
Q9C6B2 NRAMP2 Metal transporter Nramp2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SN36 NRAMP5 Metal transporter Nramp5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SNV9 NRAMP3 Metal transporter Nramp3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAPLPAAATA TASSAATPAD DEAHSLLPST PSNEEDDDDL EERAYEATEK VIVSISDFPD
70 80 90 100 110 120
ADDDEEESGL ATSTAASGIP PFSWRKLWLF TGPGFLMSIA FLDPGNLEGD LQAGAVAGDT
130 140 150 160 170 180
LLWLLLWATS MGLLVQLLAA RVGVATGRHL AELCRDEYPS WARRALWLMA EVAMVGADIQ
190 200 210 220 230 240
EVIGSAIAIK ILSRGFLPLW AGVVITALDC FIFLSLENYG VRKLEAVFAI LIATMAVSFA
250 260 270 280 290 300
WMFTDTKPNM KNLFIGILVP KLSSRTIRQA VGVVGCVIMP HNVFLHSALV QSRKIDPNKE
310 320 330 340 350 360
HQVREALRYY SIESTIALAV SFMINLFVTT VFAKGFYGTK EAGNIGLENA GQYLQEKFGG
370 380 390 400 410 420
GFFPILYIWG IGLLAAGQSS TITGTYAGQF IMGGFLNLKL KKWIRSLITR SFAIVPTIIV
430 440 450 460 470 480
ALFFDKSDSL DVLNEWLNVL QSIQIPFALI PLITLVSKEK VMGVFKIGRN TQAVTWTVAT
490 500 510 520 530 540
LLITINGYLL LDFFSSEIRG LLSGSILCVA VLAYASFVLY LILRGTELPN QIITTIRKSF
S