Q0DZE0

PR
Gene name
ZB8 (Os02g0627100, LOC_Os02g41680, OsJ_007359, P0042D01.10)
Protein name
Phenylalanine ammonia-lyase
Names
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4330040
EC number
4.3.1.24: Ammonia-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

504-574 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0DZE0

Entry ID Method Resolution Chain Position Source
AF-Q0DZE0-F1 Predicted AlphaFoldDB

No variants for Q0DZE0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0DZE0

No associated diseases with Q0DZE0

1 regional properties for Q0DZE0

Type Name Position InterPro Accession
active_site Phenylalanine/histidine ammonia-lyases, active site 195 - 211 IPR022313

Functions

Description
EC Number 4.3.1.24 Ammonia-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ammonia-lyase activity Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
phenylalanine ammonia-lyase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.

2 GO annotations of biological process

Name Definition
cinnamic acid biosynthetic process The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
L-phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P45735 PAL Phenylalanine ammonia-lyase Vitis vinifera (Grape) PR
P42357 HAL Histidine ammonia-lyase Homo sapiens (Human) PR
Q8VXG7 PAL1 Phenylalanine/tyrosine ammonia-lyase Zea mays (Maize) PR
P35492 Hal Histidine ammonia-lyase Mus musculus (Mouse) PR
P31425 PAL-1 Phenylalanine ammonia-lyase 1 Solanum tuberosum (Potato) PR
P31426 PAL-2 Phenylalanine ammonia-lyase 2 Solanum tuberosum (Potato) PR
P14717 PAL Phenylalanine ammonia-lyase Oryza sativa subsp japonica (Rice) PR
P26600 PAL5 Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P35511 PAL Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MECENGRVSA NGMSGLCVAA PRADPLNWGK ATEEMTGSHL DEVKRMVAEY RQPLVKIEGA
70 80 90 100 110 120
SLRIAQVAAV AAAGEARVEL DESARERVKA SSDWVMNSMM NGTDSYGVTT GFGATSHRRT
130 140 150 160 170 180
KEGGALQREL IRFLNAGAFG TGTDGHVLPA EATRAAMLVR INTLLQGYSG IRFEILEAIA
190 200 210 220 230 240
KLLNANVTPC LPLRGTITAS GDLVPLSYIA GLVTGRENAV AVAPDGSKVN AAEAFKIAGI
250 260 270 280 290 300
QGGFFELQPK EGLAMVNGTA VGSGLASTVL FEANILAILA EVLSAVFCEV MNGKPEYTDH
310 320 330 340 350 360
LTHKLKHHPG QIEAAAIMEH ILEGSSYMKH AKKLGELDPL MKPKQDRYAL RTSPQWLGPQ
370 380 390 400 410 420
IEVIRAATKS IEREINSVND NPLIDVSRGK ALHGGNFQGT PIGVSMDNTR LAIAAIGKLM
430 440 450 460 470 480
FAQFSELVND FYNNGLPSNL SGGRNPSLDY GFKGAEIAMA SYCSELQFLG NPVTNHVQSA
490 500 510 520 530 540
EQHNQDVNSL GLISSRKTDE AIDILKLMSS TFLIALCQAV DLRHIEENVK SAVKSCVMTV
550 560 570 580 590 600
AKKTLSTNST GDLHVARFCE KDLLKEIDRE AVFAYADDPC SHNYPLMKKL RNVLVERALA
610 620 630 640 650 660
NGAAEFNADT SVFAKVAQFE EELRATLPGA IEAARAAVEN GTAAIPSRIT ECRSYPLYRF
670 680 690 700 710
VREELGTKYL TGEKTRSPGE ELNKVLVAIN EGKHIDPLLE CLKEWNGEPL PIC