P14717

PR
Gene name
PAL (Os02g0626100, LOC_Os02g41630, B1215B07.42, OsJ_07592, P0042D01.1)
Protein name
Phenylalanine ammonia-lyase
Names
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4330034
EC number
4.3.1.24: Ammonia-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P14717

Entry ID Method Resolution Chain Position Source
AF-P14717-F1 Predicted AlphaFoldDB

No variants for P14717

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P14717

No associated diseases with P14717

1 regional properties for P14717

Type Name Position InterPro Accession
active_site Phenylalanine/histidine ammonia-lyases, active site 185 - 201 IPR022313

Functions

Description
EC Number 4.3.1.24 Ammonia-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ammonia-lyase activity Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
phenylalanine ammonia-lyase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.

2 GO annotations of biological process

Name Definition
cinnamic acid biosynthetic process The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
L-phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P45735 PAL Phenylalanine ammonia-lyase Vitis vinifera (Grape) PR
P42357 HAL Histidine ammonia-lyase Homo sapiens (Human) PR
Q8VXG7 PAL1 Phenylalanine/tyrosine ammonia-lyase Zea mays (Maize) PR
P35492 Hal Histidine ammonia-lyase Mus musculus (Mouse) PR
P31425 PAL-1 Phenylalanine ammonia-lyase 1 Solanum tuberosum (Potato) PR
P31426 PAL-2 Phenylalanine ammonia-lyase 2 Solanum tuberosum (Potato) PR
Q0DZE0 ZB8 Phenylalanine ammonia-lyase Oryza sativa subsp japonica (Rice) PR
P26600 PAL5 Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P35511 PAL Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MAGNGPINKE DPLNWGAAAA EMAGSHLDEV KRMVAQFREP LVKIQGATLR VGQVAAVAQA
70 80 90 100 110 120
KDAAGVAVEL DEEARPRVKA SSEWILNCIA HGGDIYGVTT GFGGTSHRRT KDGPALQVEL
130 140 150 160 170 180
LRHLNAGIFG TGSDGHTLPS ETVRAAMLVR INTLLQGYSG IRFEILEAIT KLLNTGVTPC
190 200 210 220 230 240
LPLRGTITAS GDLVPLSYIA GLITGRPNAQ AISPDGRKVD AAEAFKLAGI EGGFFTLNPK
250 260 270 280 290 300
EGLAIVNGTS VGSALAATVM FDANILAVLS EVLSAVFCEV MNGKPEYTDH LTHKLKHHPG
310 320 330 340 350 360
SIEAAAIMEH ILAGSSFMSH AKKVNEMDPL LKPKQDRYAL RTSPQWLGPQ IEVIRAATKS
370 380 390 400 410 420
IEREVNSVND NPVIDVHRGK ALHGGNFQGT PIGVSMDNAR LAIANIGKLM FAQFSELVNE
430 440 450 460 470 480
FYNNGLTSNL AGSRNPSLDY GFKGTEIAMA SYCSELQYLA NPITNHVQSA EQHNQDVNSL
490 500 510 520 530 540
GLVSARKTLE AVDILKLMTS TYIVALCQAV DLRHLEENIK SSVKNCVTQV AKKVLTMNPT
550 560 570 580 590 600
GDLSSARFSE KNLLTAIDRE AVFSYADDPC SANYPLMQKL RAVLVEHALT SGDAEPEASV
610 620 630 640 650 660
FSKITKFEEE LRSALPREIE AARVAVANGT APVANRIVES RSFPLYRFVR EELGCVFLTG
670 680 690 700
EKLKSPGEEC NKVFLGISQG KLIDPMLDCL KEWNGEPLPI N