P31426

PR
Gene name
PAL-2
Protein name
Phenylalanine ammonia-lyase 2
Names
Species
Solanum tuberosum (Potato)
KEGG Pathway
EC number
4.3.1.24: Ammonia-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

11-161 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P31426

Entry ID Method Resolution Chain Position Source
AF-P31426-F1 Predicted AlphaFoldDB

No variants for P31426

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P31426

No associated diseases with P31426

1 regional properties for P31426

Type Name Position InterPro Accession
active_site Phenylalanine/histidine ammonia-lyases, active site 202 - 218 IPR022313

Functions

Description
EC Number 4.3.1.24 Ammonia-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ammonia-lyase activity Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
phenylalanine ammonia-lyase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.

2 GO annotations of biological process

Name Definition
cinnamic acid biosynthetic process The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
L-phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P42357 HAL Histidine ammonia-lyase Homo sapiens (Human) PR
Q8VXG7 PAL1 Phenylalanine/tyrosine ammonia-lyase Zea mays (Maize) PR
P35492 Hal Histidine ammonia-lyase Mus musculus (Mouse) PR
P31425 PAL-1 Phenylalanine ammonia-lyase 1 Solanum tuberosum (Potato) PR
P14717 PAL Phenylalanine ammonia-lyase Oryza sativa subsp japonica (Rice) PR
Q0DZE0 ZB8 Phenylalanine ammonia-lyase Oryza sativa subsp japonica (Rice) PR
P35511 PAL Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MAPSIAQNEH INGEVKEVLW NLCKKQNYLP LNWEMAADSL RGSKLDQVKK MVDEFRKPIV
70 80 90 100 110 120
KLGGETLTVA QVASIANVDN KSNGVRVELS ESARAGVKAS SDWVMDSMSK GTDSYGVTTG
130 140 150 160 170 180
FGATSHRRTK NGGTLQKNLI RFLNAGVFGI GTESTHTLPH SATRAAMLVR INTLLQGYSG
190 200 210 220 230 240
IRFEILEAIT KLINSNISPC LPLRGTVTAS GDLVPLSYIA GLLTGRPNSK AVGPTGSKLD
250 260 270 280 290 300
AEEAFRVAGV TGGFFELQPK EGLALVNGTA VGSAMASIVL FESNILAVMF EVLSAIFAEV
310 320 330 340 350 360
MNGKPEFTDY LTHKLKHHPG QIEAAAIMEH ILDGSSYVKA AQKLHEMDPL QKPKQDRYAL
370 380 390 400 410 420
RTSPQWLGPQ IEVIRAATKM IEREINSVND NPLIDVSRNK AIHGGNFQGT PIGVSMDNTR
430 440 450 460 470 480
LALASIGKLM FAQFSELVND YYNNGLPSNL TAGRNPSLDY GFKGAEIAMA SYCSELQFLA
490 500 510 520 530 540
NPVTNHVQSA EQHNQDVNSL GLISARKTAE AVDILKLMSS TYLVALCQAI DLRHLEENLK
550 560 570 580
SVVKNTVSQV AKRTLTIGVL GELHPARFCE KELLRVVDRE YLFAYADDPC