P31425

PR
Gene name
PAL-1
Protein name
Phenylalanine ammonia-lyase 1
Names
Species
Solanum tuberosum (Potato)
KEGG Pathway
EC number
4.3.1.24: Ammonia-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

81-161 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P31425

Entry ID Method Resolution Chain Position Source
AF-P31425-F1 Predicted AlphaFoldDB

No variants for P31425

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P31425

No associated diseases with P31425

1 regional properties for P31425

Type Name Position InterPro Accession
active_site Phenylalanine/histidine ammonia-lyases, active site 202 - 218 IPR022313

Functions

Description
EC Number 4.3.1.24 Ammonia-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ammonia-lyase activity Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
phenylalanine ammonia-lyase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.

2 GO annotations of biological process

Name Definition
cinnamic acid biosynthetic process The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
L-phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P45735 PAL Phenylalanine ammonia-lyase Vitis vinifera (Grape) PR
P42357 HAL Histidine ammonia-lyase Homo sapiens (Human) PR
Q8VXG7 PAL1 Phenylalanine/tyrosine ammonia-lyase Zea mays (Maize) PR
P35492 Hal Histidine ammonia-lyase Mus musculus (Mouse) PR
P31426 PAL-2 Phenylalanine ammonia-lyase 2 Solanum tuberosum (Potato) PR
P14717 PAL Phenylalanine ammonia-lyase Oryza sativa subsp japonica (Rice) PR
Q0DZE0 ZB8 Phenylalanine ammonia-lyase Oryza sativa subsp japonica (Rice) PR
P26600 PAL5 Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P35511 PAL Phenylalanine ammonia-lyase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MAPSIAQNGH VNGEVEEVLW KKSIHDPLNW EMAVDSLRGS HLDEVKKMVD EFRKPIVKLW
70 80 90 100 110 120
GETLTVAQVA SIANADNKTS GFKVELSESA RAGVKASSDW VMDSMSKGTD SYGVTTGFCA
130 140 150 160 170 180
TSHRRTKNGG ALQKELIKFL NAGVFGNGTE STHTLPHSAT RAAMLVRINT LLQGYSGIRF
190 200 210 220 230 240
EILEAITKLI NSNITPCLPL RGTVTASGDL VPLSYIAGLL TGRPNSKAVG PSGSKLDADE
250 260 270 280 290 300
AFRVAAVSGG FFELQPKEGL ALVNGTAVGS GMASIVLYDS NILAVMFEVL SAIFAEVMNG
310 320 330 340 350 360
KPEFTDYLTH KLKHHPGQIE AAAIMEHILD GSSYVKAAQK LHEMDPLQKP KQDRYALRTS
370 380 390 400 410 420
PQWLGPQIEV IRAATKMIER EINSVNDNPL IDVSRNKAIH GGNFQGTPIG VSMDNTRLAL
430 440 450 460 470 480
ASIGKLMFAQ FSELVNDYYN NGLPSNLTAG RNPSLDYGFK GAEIAMASYC SELQFLANPV
490 500 510 520 530 540
TNHVQSAEQH NQDVNSLGLI SARKTAEAVD ILKLMSSTYL VALCQAIDLR HLEENLKSVV
550 560 570 580 590 600
KNTVSQVAKR TLTIGAIGEL HPARFCEKEL LRVVDREYLF TYADDPCSST YPLMQKLRQV
610 620 630 640 650 660
LVDHAMKNGE SEKNINSSIF QKIGAFEDEL NAVLPKEVES ARALLESGNP SIPNRITECR
670 680 690 700 710
SYPLYRLVRQ ELGTELLTGE KVRSPGEEIE KVFTAMCNGQ INDPLLECLK SWNGAPLPIC