P45735
Gene name |
PAL |
Protein name |
Phenylalanine ammonia-lyase |
Names |
|
Species |
Vitis vinifera (Grape) |
KEGG Pathway |
|
EC number |
4.3.1.24: Ammonia-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P45735
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P45735-F1 | Predicted | AlphaFoldDB |
No variants for P45735
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P45735 | |||||
No associated diseases with P45735
1 regional properties for P45735
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Phenylalanine/histidine ammonia-lyases, active site | 203 - 219 | IPR022313 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.3.1.24 | Ammonia-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phenylalanine ammonia-lyase activity | Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cinnamic acid biosynthetic process | The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid. |
| L-phenylalanine catabolic process | The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P42357 | HAL | Histidine ammonia-lyase | Homo sapiens (Human) | PR |
| Q8VXG7 | PAL1 | Phenylalanine/tyrosine ammonia-lyase | Zea mays (Maize) | PR |
| P35492 | Hal | Histidine ammonia-lyase | Mus musculus (Mouse) | PR |
| P31425 | PAL-1 | Phenylalanine ammonia-lyase 1 | Solanum tuberosum (Potato) | PR |
| P14717 | PAL | Phenylalanine ammonia-lyase | Oryza sativa subsp japonica (Rice) | PR |
| Q0DZE0 | ZB8 | Phenylalanine ammonia-lyase | Oryza sativa subsp japonica (Rice) | PR |
| P26600 | PAL5 | Phenylalanine ammonia-lyase | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| TDHLTHKLKH | HPGQIEAAAI | MEHILDGSSY | VKEAKKLHEM | DPLQKPKQDR | YALRTSPQWL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GPHIEVIRAS | TKSIEREINS | VNDNPLIDVS | RNKALHGGNF | QGTPIGVSMD | NTRLAIAAIG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLMFAQFSEL | VNDFYNNGLP | SNLSGSRNPS | LDYGFKGAEI | AMASYCSELQ | FLANPVTNHV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ESAEQHNQDV | NSLGLISSRK | TAEAVDILKL | MSTTYLVALC | QAIDLRHLEE | NLKSTVKKTV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SHVAKKTLTI | GANGELHPSR | FCEKDLLKVV | DREHVFAYID | DPCSATYPLM | QKVRQVLVEH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ALNNGESEKN | GSTSIFQKIG | AFEEELKAVL | PKEVESARDG | VESGNPSIPN | RIKECRSYPL |
| 370 | 380 | 390 | 400 | 410 | |
| YKFVREELGT | GLLTGEKVRS | PGEDFDKVFT | AMCEGKIIDP | LLDCLSAWNG | APLPIC |