P38546
Gene name |
RAN1 |
Protein name |
GTP-binding nuclear protein Ran1 |
Names |
Ras-related nuclear protein 1 |
Species |
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
KEGG Pathway |
sly:778289 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P38546
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P38546-F1 | Predicted | AlphaFoldDB |
No variants for P38546
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P38546 | |||||
No associated diseases with P38546
1 regional properties for P38546
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 14 - 164 | IPR005225 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into nucleus | The directed movement of a protein from the cytoplasm to the nucleus. |
| ribosomal subunit export from nucleus | The directed movement of a ribosomal subunit from the nucleus into the cytoplasm. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P32836 | GSP2 | GTP-binding nuclear protein GSP2/CNR2 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P32835 | GSP1 | GTP-binding nuclear protein GSP1/CNR1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P42558 | RAN | GTP-binding nuclear protein Ran | Gallus gallus (Chicken) | PR |
| Q9VZ23 | Ran | GTP-binding nuclear protein Ran | Drosophila melanogaster (Fruit fly) | PR |
| Q7F7I7 | RAN1 | GTP-binding nuclear protein Ran-1 | Oryza sativa subsp japonica (Rice) | PR |
| Q7GD79 | RAN2 | GTP-binding nuclear protein Ran-2 | Oryza sativa subsp japonica (Rice) | PR |
| O17915 | ran-1 | GTP-binding nuclear protein ran-1 | Caenorhabditis elegans | PR |
| P41916 | RAN1 | GTP-binding nuclear protein Ran-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P41917 | RAN2 | GTP-binding nuclear protein Ran-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8H156 | RAN3 | GTP-binding nuclear protein Ran-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P38547 | RAN2 | GTP-binding nuclear protein Ran2 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
| Q6GL85 | ran | GTP-binding nuclear protein Ran | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALPNQQTVD | YPSFKLVIVG | DGGTGKTTFV | KRHLTGEFEK | KYEPTIGVEV | HPLDFFTNCG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KIRFYCWDTA | GQEKFGGLRD | GYYIHGQCAI | IMFDVTARLT | YKNVPTWHRD | LCRVCENIPI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VLCGNKVDVK | NRQVKAKQVT | FHRKKNLQYY | EISAKSNYNF | EKPFLYLARK | LAGDGNLHFV |
| 190 | 200 | 210 | 220 | ||
| ESPALAPPEV | HIDLAAQALH | EEELQQAANQ | PLPDDDDEAF | E |