P32836

PR
Gene name
GSP2 (CNR2, YOR185C)
Protein name
GTP-binding nuclear protein GSP2/CNR2
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR185C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

155-220 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P32836

Entry ID Method Resolution Chain Position Source
AF-P32836-F1 Predicted AlphaFoldDB

2 variants for P32836

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-682100 3 A>V No SGRP
s15-682083 9 A>T No SGRP

No associated diseases with P32836

1 regional properties for P32836

Type Name Position InterPro Accession
domain Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain 331 - 488 IPR032319

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

4 GO annotations of biological process

Name Definition
nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
poly(A)+ mRNA export from nucleus The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus.
ribosomal subunit export from nucleus The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P32835 GSP1 GTP-binding nuclear protein GSP1/CNR1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P42558 RAN GTP-binding nuclear protein Ran Gallus gallus (Chicken) PR
Q9VZ23 Ran GTP-binding nuclear protein Ran Drosophila melanogaster (Fruit fly) PR
Q7GD79 RAN2 GTP-binding nuclear protein Ran-2 Oryza sativa subsp japonica (Rice) PR
Q7F7I7 RAN1 GTP-binding nuclear protein Ran-1 Oryza sativa subsp japonica (Rice) PR
O17915 ran-1 GTP-binding nuclear protein ran-1 Caenorhabditis elegans PR
Q8H156 RAN3 GTP-binding nuclear protein Ran-3 Arabidopsis thaliana (Mouse-ear cress) PR
P41916 RAN1 GTP-binding nuclear protein Ran-1 Arabidopsis thaliana (Mouse-ear cress) PR
P41917 RAN2 GTP-binding nuclear protein Ran-2 Arabidopsis thaliana (Mouse-ear cress) PR
P38546 RAN1 GTP-binding nuclear protein Ran1 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P38547 RAN2 GTP-binding nuclear protein Ran2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
Q6GL85 ran GTP-binding nuclear protein Ran Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MSAPAQNNAE VPTFKLVLVG DGGTGKTTFV KRHLTGEFEK KYIATIGVEV HPLSFYTNFG
70 80 90 100 110 120
EIKFDVWDTA GQEKFGGLRD GYYINAQCAI IMFDVTSRIT YKNVPNWHRD LVRVCENIPI
130 140 150 160 170 180
VLCGNKVDVK ERKVKAKTIT FHRKKNLQYY DISAKSNYNF EKPFLWLARK LAGNPQLEFV
190 200 210
ASPALAPPEV QVDEQLMHQY QQEMDQATAL PLPDEDDADL