P28554
Gene name |
PDS |
Protein name |
15-cis-phytoene desaturase, chloroplastic/chromoplastic |
Names |
Phytoene dehydrogenase, Phytoene desaturase |
Species |
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
KEGG Pathway |
sly:544073 |
EC number |
1.3.5.5: With a quinone or related compound as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P28554
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P28554-F1 | Predicted | AlphaFoldDB |
17 variants for P28554
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| vcZ187EC3 | 20 | Y>N | No | Ensembl | |
| vcZ187EC5 | 32 | E>K | No | Ensembl | |
| vcZ187EC6 | 39 | Q>L | No | Ensembl | |
| vcZ187EC6 | 39 | Q>P | No | Ensembl | |
| vcZ187ECA | 66 | R>G | No | Ensembl | |
| vcZ187ECB | 67 | L>S | No | Ensembl | |
| vcZ187ECC | 71 | L>S | No | Ensembl | |
| vcZ187ECO | 102 | F>I | No | Ensembl | |
| vcZ187EEI | 126 | T>A | No | Ensembl | |
| vcZ187EHD | 294 | D>E | No | Ensembl | |
| vcZ187EJ7 | 330 | M>V | No | Ensembl | |
| vcZ187EJD | 356 | E>Q | No | Ensembl | |
| vcZ187EKL | 424 | T>A | No | Ensembl | |
| vcZ187EN1 | 485 | T>A | No | Ensembl | |
| vcZ187EN3 | 507 | K>R | No | Ensembl | |
| vcZ187ENJ | 525 | L>I | No | Ensembl | |
| vcZ187EP0 | 572 | R>H | No | Ensembl |
No associated diseases with P28554
1 regional properties for P28554
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Amine oxidase | 121 - 562 | IPR002937 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.3.5.5 | With a quinone or related compound as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chromoplast | A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
| phytoene dehydrogenase activity | Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| carotene biosynthetic process | The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids. |
| carotenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P56560 | MAOB | Amine oxidase [flavin-containing] B | Bos taurus (Bovine) | PR |
| P21398 | MAOA | Amine oxidase [flavin-containing] A | Bos taurus (Bovine) | PR |
| Q8NB78 | KDM1B | Lysine-specific histone demethylase 2 | Homo sapiens (Human) | PR |
| P21397 | MAOA | Amine oxidase [flavin-containing] A | Homo sapiens (Human) | PR |
| P27338 | MAOB | Amine oxidase [flavin-containing] B | Homo sapiens (Human) | PR |
| O60341 | KDM1A | Lysine-specific histone demethylase 1A | Homo sapiens (Human) | PR |
| Q64133 | Maoa | Amine oxidase [flavin-containing] A | Mus musculus (Mouse) | PR |
| Q6ZQ88 | Kdm1a | Lysine-specific histone demethylase 1A | Mus musculus (Mouse) | PR |
| Q6Q2J0 | MAOA | Amine oxidase [flavin-containing] A | Sus scrofa (Pig) | PR |
| P19643 | Maob | Amine oxidase [flavin-containing] B | Rattus norvegicus (Rat) | PR |
| P21396 | Maoa | Amine oxidase [flavin-containing] A | Rattus norvegicus (Rat) | PR |
| Q6NSN2 | mao | Amine oxidase [flavin-containing] | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPQIGLVSAV | NLRVQGSSAY | LWSSRSSSLG | TESRDGCLQR | NSLCFAGSES | MGHKLKIRTP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HATTRRLVKD | LGPLKVVCID | YPRPELDNTV | NYLEAAFLSS | TFRASPRPTK | PLEIVIAGAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LGGLSTAKYL | ADAGHKPILL | EARDVLGGKV | AAWKDDDGDW | YETGLHIFFG | AYPNIQNLFG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELGINDRLQW | KEHSMIFAMP | SKPGEFSRFD | FSEALPAPLN | GILAILKNNE | MLTWPEKVKF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AIGLLPAMLG | GQSYVEAQDG | ISVKDWMRKQ | GVPDRVTDEV | FIAMSKALNF | INPDELSMQC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ILIALNRFLQ | EKHGSKMAFL | DGNPPERLCM | PIVEHIESKG | GQVRLNSRIK | KIELNEDGSV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KSFILSDGSA | IEGDAFVFAA | PVDIFKLLLP | EDWKEIPYFQ | KLEKLVGVPV | INVHIWFDRK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LKNTYDHLLF | SRSSLLSVYA | DMSVTCKEYY | NPNQSMLELV | FAPAEEWISR | SDSEIIDATM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KELATLFPDE | ISADQSKAKI | LKYHVVKTPR | SVYKTVPGCE | PCRPLQRSPI | EGFYLAGDYT |
| 550 | 560 | 570 | 580 | ||
| KQKYLASMEG | AVLSGKLCAQ | AIVQDYELLV | GRSQKKLSEA | SVV |