O35403
Gene name |
Sult3a1 (St3a1) |
Protein name |
Amine sulfotransferase |
Names |
SULT-X2, Sulfotransferase 3A1, ST3A1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
|
EC number |
2.8.2.3: Sulfotransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O35403
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7V1O | X-ray | 240 A | A/B | 1-293 | PDB |
| AF-O35403-F1 | Predicted | AlphaFoldDB |
No variants for O35403
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O35403 | |||||
No associated diseases with O35403
1 regional properties for O35403
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Phox homology | 1 - 123 | IPR001683 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.8.2.3 | Sulfotransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| amine sulfotransferase activity | Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate. |
| sulfotransferase activity | Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sulfation | The addition of a sulfate group to a molecule. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P19217 | SULT1E1 | Sulfotransferase 1E1 | Bos taurus (Bovine) | PR |
| Q06520 | SULT2A1 | Sulfotransferase 2A1 | Homo sapiens (Human) | PR |
| P49888 | SULT1E1 | Sulfotransferase 1E1 | Homo sapiens (Human) | PR |
| Q9BR01 | SULT4A1 | Sulfotransferase 4A1 | Homo sapiens (Human) | PR |
| P0CC03 | Sult6b1 | Sulfotransferase 6B1 | Mus musculus (Mouse) | PR |
| P49891 | Sult1e1 | Sulfotransferase 1E1 | Mus musculus (Mouse) | PR |
| Q3UZZ6 | Sult1d1 | Sulfotransferase 1 family member D1 | Mus musculus (Mouse) | PR |
| P49890 | Ste2 | Estrogen sulfotransferase Ste2 | Rattus norvegicus (Rat) | PR |
| P17988 | Sult1a1 | Sulfotransferase 1A1 | Rattus norvegicus (Rat) | PR |
| Q9FX55 | STO9 | Cytosolic sulfotransferase 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9STQ6 | SOT3 | Cytosolic sulfotransferase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDNKDEYLLN | FKGYNFQKTL | VKMEVVENIE | NYEIRDDDIF | IVTYPKSGTI | WTQQILSLIY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FEGHRNRTEN | IETIDRAPFF | EYNIHKLDYA | KMPSPRIFSS | HIPYYLVPKG | LKDKKAKILY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MYRNPKDVLI | SYFHFSNLML | IFQNPDTVES | FMQTFLDGDV | VGSLWFDHIR | GWYEHRHDFN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IMFMSFEDMK | KDFRSSVLKI | CSFLEKELSE | EDVDAVVRQA | TFQKMKADPR | ANYEHIIKDE |
| 250 | 260 | 270 | 280 | 290 | |
| LGTRNEMGSF | LRKGVVGAWK | HYLTVDQSER | FDKIFHRNMK | NIPLKFIWDI | NEE |