Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SXD9

Entry ID Method Resolution Chain Position Source
AF-Q9SXD9-F1 Predicted AlphaFoldDB

229 variants for Q9SXD9

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_23173336_G_A 2 V>I No 1000Genomes
ENSVATH05037979 4 A>S No 1000Genomes
ENSVATH05037979 4 A>T No 1000Genomes
tmp_1_23173343_C_T 4 A>V No 1000Genomes
tmp_1_23173352_C_T 7 P>L No 1000Genomes
ENSVATH13699005 8 P>L No 1000Genomes
ENSVATH01440698 12 N>H No 1000Genomes
tmp_1_23173372_G_A 14 V>M No 1000Genomes
ENSVATH01440699 15 A>V No 1000Genomes
ENSVATH13699013 18 G>D No 1000Genomes
ENSVATH13699012 18 G>S No 1000Genomes
ENSVATH05037980 19 A>V No 1000Genomes
ENSVATH14390689 20 G>E No 1000Genomes
ENSVATH01440701 20 G>R No 1000Genomes
tmp_1_23173394_C_T 21 A>V No 1000Genomes
ENSVATH14390690 22 A>T No 1000Genomes
ENSVATH14390691 23 G>E No 1000Genomes
ENSVATH05037982 23 G>R No 1000Genomes
ENSVATH05037983 24 L>F No 1000Genomes
ENSVATH05037983 24 L>V No 1000Genomes
ENSVATH05037984 25 V>L No 1000Genomes
ENSVATH13699016 26 A>V No 1000Genomes
tmp_1_23173414_C_T 28 R>* No 1000Genomes
ENSVATH05037986 30 L>F No 1000Genomes
ENSVATH05037986 30 L>V No 1000Genomes
ENSVATH13699019 31 R>C No 1000Genomes
tmp_1_23173424_G_A 31 R>H No 1000Genomes
ENSVATH01440703 32 R>L No 1000Genomes
ENSVATH13699022 35 H>Y No 1000Genomes
ENSVATH01440704 37 V>I No 1000Genomes
tmp_1_23173447_G_A 39 V>I No 1000Genomes
ENSVATH07670195 40 F>L No 1000Genomes
ENSVATH13699024 41 E>K No 1000Genomes
ENSVATH07670199 42 R>C No 1000Genomes
ENSVATH01440705 42 R>H No 1000Genomes
ENSVATH01440705 42 R>P No 1000Genomes
ENSVATH05037987 43 G>E No 1000Genomes
tmp_1_23173463_A_G 44 N>S No 1000Genomes
ENSVATH01440707 45 H>Q No 1000Genomes
ENSVATH01440708 49 V>M No 1000Genomes
tmp_1_23173482_G_A 50 W>* No 1000Genomes
tmp_1_23173483_G_A 51 A>T No 1000Genomes
ENSVATH13699025 51 A>V No 1000Genomes
tmp_1_23173490_C_T 53 T>M No 1000Genomes
ENSVATH00114243 54 P>S No 1000Genomes
tmp_1_23173498_G_A 56 V>I No 1000Genomes
ENSVATH13699026 57 E>K No 1000Genomes
ENSVATH01440709 58 P>L No 1000Genomes
ENSVATH05037990 59 D>N No 1000Genomes
ENSVATH05037991 61 L>F No 1000Genomes
ENSVATH05037993 63 I>T No 1000Genomes
ENSVATH13699027 64 D>N No 1000Genomes
tmp_1_23173523_A_T 64 D>V No 1000Genomes
tmp_1_23173525_C_T 65 P>S No 1000Genomes
tmp_1_23173531_C_T 67 R>* No 1000Genomes
ENSVATH05037994 68 P>S No 1000Genomes
ENSVATH13699030 69 V>I No 1000Genomes
ENSVATH14390694 71 H>Y No 1000Genomes
ENSVATH05037995 72 S>L No 1000Genomes
tmp_1_23173549_AG_TG,A 73 S>C No 1000Genomes
ENSVATH04064652 73 S>N No 1000Genomes
tmp_1_23173562_C_T,A 77 S>F No 1000Genomes
tmp_1_23173562_C_T,A 77 S>Y No 1000Genomes
ENSVATH05038000 79 R>* No 1000Genomes
ENSVATH01440711 79 R>Q No 1000Genomes
tmp_1_23173571_C_T 80 T>I No 1000Genomes
tmp_1_23173574_T_C 81 I>T No 1000Genomes
tmp_1_23173576_A_G 82 I>V No 1000Genomes
tmp_1_23173580_C_T 83 P>L No 1000Genomes
ENSVATH13699031 83 P>T No 1000Genomes
tmp_1_23173582_C_T 84 Q>* No 1000Genomes
ENSVATH01440712 84 Q>R No 1000Genomes
ENSVATH01440713 85 E>* No 1000Genomes
ENSVATH01440713 85 E>K No 1000Genomes
tmp_1_23173593_G_C 87 M>I No 1000Genomes
ENSVATH05038004 88 G>S No 1000Genomes
ENSVATH05038006 91 D>N No 1000Genomes
ENSVATH01440714 92 F>L No 1000Genomes
tmp_1_23173610_C_T 93 P>L No 1000Genomes
ENSVATH13699034 93 P>S No 1000Genomes
ENSVATH01440715 95 S>L No 1000Genomes
ENSVATH14390729 96 T>N No 1000Genomes
ENSVATH05038008 97 R>G No 1000Genomes
ENSVATH13699036 97 R>I No 1000Genomes
tmp_1_23173624_C_T 98 L>F No 1000Genomes
ENSVATH05038009 99 E>K No 1000Genomes
ENSVATH01440716 101 G>R No 1000Genomes
tmp_1_23173640_G_C 103 R>T No 1000Genomes
ENSVATH14390731 107 R>K No 1000Genomes
ENSVATH01440717 109 P>S No 1000Genomes
ENSVATH01440717 109 P>T No 1000Genomes
ENSVATH01440718 110 G>C No 1000Genomes
tmp_1_23173661_G_A 110 G>D No 1000Genomes
ENSVATH01440718 110 G>S No 1000Genomes
ENSVATH05038011 112 S>I No 1000Genomes
ENSVATH05038011 112 S>N No 1000Genomes
tmp_1_23173668_T_A 112 S>R No 1000Genomes
ENSVATH13699038 113 E>D No 1000Genomes
tmp_1_23173669_G_A 113 E>K No 1000Genomes
tmp_1_23173672_G_A 114 V>I No 1000Genomes
ENSVATH13699039 115 L>F No 1000Genomes
ENSVATH01440719 116 A>S No 1000Genomes
ENSVATH01440719 116 A>T No 1000Genomes
ENSVATH05038012 119 R>K No 1000Genomes
tmp_1_23173690_G_A 120 D>N No 1000Genomes
tmp_1_23173693_T_C 121 F>L No 1000Genomes
ENSVATH00114244 122 V>A No 1000Genomes
tmp_1_23173700_G_T 123 R>M No 1000Genomes
ENSVATH05038014 123 R>S No 1000Genomes
tmp_1_23173702_G_A 124 E>K No 1000Genomes
ENSVATH01440720 128 E>D No 1000Genomes
ENSVATH05038015 130 M>I No 1000Genomes
ENSVATH14390732 130 M>K No 1000Genomes
tmp_1_23173726_C_T 132 R>C No 1000Genomes
ENSVATH05038016 132 R>H No 1000Genomes
ENSVATH05038016 132 R>P No 1000Genomes
tmp_1_23173732_G_A 134 E>K No 1000Genomes
ENSVATH13699040 135 T>M No 1000Genomes
ENSVATH01440721 137 V>I No 1000Genomes
ENSVATH05038019 138 V>M No 1000Genomes
ENSVATH13699042 139 R>K No 1000Genomes
ENSVATH05038020 140 V>I No 1000Genomes
ENSVATH14390733 141 E>K No 1000Genomes
ENSVATH05038021 142 Q>H No 1000Genomes
tmp_1_23173763_G_A,C 144 G>A No 1000Genomes
tmp_1_23173763_G_A,C 144 G>E No 1000Genomes
ENSVATH01440723 144 G>R No 1000Genomes
ENSVATH01440723 144 G>W No 1000Genomes
ENSVATH01440724 145 E>K No 1000Genomes
tmp_1_23173772_C_T 147 P>L No 1000Genomes
tmp_1_23173771_C_T 147 P>S No 1000Genomes
ENSVATH13699043 148 K>R No 1000Genomes
ENSVATH13699044 149 K>N No 1000Genomes
ENSVATH05038023 150 W>* No 1000Genomes
tmp_1_23173784_G_A 151 R>K No 1000Genomes
ENSVATH13699045 152 V>F No 1000Genomes
ENSVATH13699045 152 V>I No 1000Genomes
tmp_1_23173789_A_G 153 K>E No 1000Genomes
ENSVATH01440726 153 K>N No 1000Genomes
ENSVATH01440727 154 S>F No 1000Genomes
ENSVATH01440727 154 S>Y No 1000Genomes
tmp_1_23173796_G_A 155 R>K No 1000Genomes
ENSVATH05038024 155 R>S No 1000Genomes
tmp_1_23173801_T_G 157 F>V No 1000Genomes
tmp_1_23173805_G_A 158 G>D No 1000Genomes
ENSVATH05038027 158 G>S No 1000Genomes
ENSVATH13699046 162 D>N No 1000Genomes
ENSVATH14390734 163 E>* No 1000Genomes
ENSVATH00114245 165 Y>C No 1000Genomes
ENSVATH05038028 166 D>N No 1000Genomes
ENSVATH13699047 167 A>T No 1000Genomes
tmp_1_23173832_C_T 167 A>V No 1000Genomes
tmp_1_23173835_T_C 168 V>A No 1000Genomes
ENSVATH13699048 169 V>F No 1000Genomes
ENSVATH13699048 169 V>I No 1000Genomes
ENSVATH13699048 169 V>L No 1000Genomes
ENSVATH13699049 170 V>A No 1000Genomes
ENSVATH05038029 170 V>I No 1000Genomes
ENSVATH13699050 171 C>Y No 1000Genomes
ENSVATH05038031 173 G>D No 1000Genomes
ENSVATH05038030 173 G>S No 1000Genomes
ENSVATH13699052 175 Y>N No 1000Genomes
ENSVATH05038032 176 T>I No 1000Genomes
ENSVATH05038032 176 T>R No 1000Genomes
ENSVATH05038033 177 E>D No 1000Genomes
ENSVATH05038034 179 R>C No 1000Genomes
ENSVATH05038035 179 R>H No 1000Genomes
ENSVATH05038037 181 A>V No 1000Genomes
ENSVATH13699053 183 I>L No 1000Genomes
tmp_1_23173883_C_T 184 P>L No 1000Genomes
tmp_1_23173882_C_T 184 P>S No 1000Genomes
ENSVATH05038059 185 G>D No 1000Genomes
tmp_1_23175692_A_T 188 T>S No 1000Genomes
tmp_1_23175719_C_T 197 H>Y No 1000Genomes
tmp_1_23175731_G_A 201 V>I No 1000Genomes
tmp_1_23175739_A_T 203 E>D No 1000Genomes
tmp_1_23175743_G_T 205 V>F No 1000Genomes
ENSVATH05038060 206 K>Q No 1000Genomes
tmp_1_23175752_C_G 208 Q>E No 1000Genomes
tmp_1_23175753_A_C 208 Q>P No 1000Genomes
ENSVATH05038063 220 V>A No 1000Genomes
ENSVATH13699287 224 R>I No 1000Genomes
tmp_1_23175877_C_A 225 D>E No 1000Genomes
ENSVATH01440774 241 K>T No 1000Genomes
tmp_1_23175937_C_G 245 Y>* No 1000Genomes
tmp_1_23175938_G_A 246 E>K No 1000Genomes
ENSVATH13699288 249 P>S No 1000Genomes
ENSVATH05038066 252 D>E No 1000Genomes
tmp_1_23175971_C_T 257 H>Y No 1000Genomes
ENSVATH01440775 258 S>T No 1000Genomes
tmp_1_23175978_A_G 259 N>S No 1000Genomes
ENSVATH13699293 261 E>* No 1000Genomes
ENSVATH13699294 261 E>G No 1000Genomes
tmp_1_23176074_C_G 264 R>G No 1000Genomes
ENSVATH05038069 267 G>D No 1000Genomes
ENSVATH13699298 272 K>R No 1000Genomes
ENSVATH05038070 276 T>M No 1000Genomes
tmp_1_23176110_A_C 276 T>P No 1000Genomes
ENSVATH05038071 279 A>T No 1000Genomes
tmp_1_23176120_C_T 279 A>V No 1000Genomes
ENSVATH13699303 287 G>E No 1000Genomes
ENSVATH05038075 289 K>I No 1000Genomes
ENSVATH13699305 299 G>C No 1000Genomes
ENSVATH14390848 303 V>F No 1000Genomes
tmp_1_23176273_A_G 306 N>S No 1000Genomes
tmp_1_23176275_C_T 307 R>C No 1000Genomes
tmp_1_23176305_C_T 317 P>S No 1000Genomes
ENSVATH13699307 320 L>F No 1000Genomes
ENSVATH05038081 328 G>E No 1000Genomes
ENSVATH05038084 340 E>D No 1000Genomes
ENSVATH13699310 344 K>E No 1000Genomes
ENSVATH01440790 351 A>T No 1000Genomes
tmp_1_23176498_C_T 351 A>V No 1000Genomes
tmp_1_23176519_C_T 358 S>L No 1000Genomes
ENSVATH00114247 359 Q>L No 1000Genomes
tmp_1_23176544_G_C 366 K>N No 1000Genomes
ENSVATH01440793 370 L>S No 1000Genomes
ENSVATH01440794 371 K>M No 1000Genomes
ENSVATH13699314 379 K>E No 1000Genomes
ENSVATH05038085 382 T>S No 1000Genomes
ENSVATH01440796 383 H>Q No 1000Genomes
ENSVATH13699315 385 M>I No 1000Genomes
tmp_1_23176612_A_T 389 D>V No 1000Genomes
ENSVATH01440799 395 N>D No 1000Genomes
ENSVATH05038088 398 L>V No 1000Genomes
ENSVATH09351418 406 R>Q No 1000Genomes
ENSVATH01440802 426 A>S No 1000Genomes
ENSVATH09351419 427 S>N No 1000Genomes
ENSVATH09351420 435 D>N No 1000Genomes

No associated diseases with Q9SXD9

No regional properties for Q9SXD9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SXD9

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
guanylate cyclase activity Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
N,N-dimethylaniline monooxygenase activity Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
nitric oxide binding Binding to nitric oxide (NO).
oxygen binding Binding to oxygen (O2).

1 GO annotations of biological process

Name Definition
stomatal closure The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P31512 FMO4 Dimethylaniline monooxygenase [N-oxide-forming] 4 Homo sapiens (Human) PR
P49326 FMO5 Flavin-containing monooxygenase 5 Homo sapiens (Human) PR
P97501 Fmo3 Dimethylaniline monooxygenase [N-oxide-forming] 3 Mus musculus (Mouse) PR
P97872 Fmo5 Flavin-containing monooxygenase 5 Mus musculus (Mouse) PR
Q8K2I3 Fmo2 Dimethylaniline monooxygenase [N-oxide-forming] 2 Mus musculus (Mouse) PR
Q8VHG0 Fmo4 Dimethylaniline monooxygenase [N-oxide-forming] 4 Mus musculus (Mouse) PR
Q8K4B7 Fmo4 Dimethylaniline monooxygenase [N-oxide-forming] 4 Rattus norvegicus (Rat) PR
Q9EQ76 Fmo3 Dimethylaniline monooxygenase [N-oxide-forming] 3 Rattus norvegicus (Rat) PR
Q6IRI9 Fmo2 Dimethylaniline monooxygenase [N-oxide-forming] 2 Rattus norvegicus (Rat) PR
Q8K4C0 Fmo5 Flavin-containing monooxygenase 5 Rattus norvegicus (Rat) PR
Q9SVU0 YUC8 Probable indole-3-pyruvate monooxygenase YUCCA8 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C8T8 At1g63340 Putative flavin-containing monooxygenase FMO GS-OX-like 10 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVPAVNPPTT SNHVAVIGAG AAGLVAAREL RREGHSVVVF ERGNHIGGVW AYTPNVEPDP
70 80 90 100 110 120
LSIDPTRPVI HSSLYSSLRT IIPQECMGFT DFPFSTRLEN GSRDPRRHPG HSEVLAYLRD
130 140 150 160 170 180
FVREFKIEEM IRFETEVVRV EQAGENPKKW RVKSRNFGDI SDEIYDAVVV CNGHYTEPRH
190 200 210 220 230 240
ALIPGIDTWP GKQIHSHNYR VPEQVKDQVV VVIGSSVSGV DISRDIANVT KEVHISSRST
250 260 270 280 290 300
KPETYEKLPG YDNLWLHSNI ETVREDGSVV FKNGKTVYAD TIMHCTGYKY YFPFLDTKGE
310 320 330 340 350 360
VTVEDNRVGP LYKHVFPPAL SPGLSFIGLP WQVIPFPMFE LQSKWVAAVL AGRVSLPSQE
370 380 390 400 410 420
EMEDTKMFYL KLEASCIPKR YTHLMAELDS QFVYNNWLAD QCDYPRIEKW REQMFYKVFK
430 440 450 460
RIQSQASTYK DDWDDDHLIA EAYEDFVKFP SNYPSSLIER EYTS