AiPD: Autoinhibited Protein Database

P31512

Gene name	FMO4 (FMO2)
Protein name	Dimethylaniline monooxygenase [N-oxide-forming] 4
Names	Dimethylaniline oxidase 4, Hepatic flavin-containing monooxygenase 4, FMO 4
Species	Homo sapiens (Human)
KEGG Pathway	hsa:2329
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

379-452 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

379-452 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for P31512

Entry ID	Method	Resolution	Chain	Position	Source
AF-P31512-F1	Predicted				AlphaFoldDB

451 variants for P31512

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs1403195183 CA343171268	3	K>Q		No	ClinGen gnomAD
rs1353341129 CA343171274	3	K>R		No	ClinGen TOPMed
TCGA novel	4	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1241903 rs200011265	4	K>R		No	ClinGen ExAC TOPMed gnomAD
CA32523843 rs200011265	4	K>T		No	ClinGen ExAC TOPMed gnomAD
rs1303319200 CA343171318	5	V>A		No	ClinGen gnomAD
rs1377144297 CA343171330	6	A>E		No	ClinGen TOPMed
rs1415354699 CA343171322	6	A>T		No	ClinGen TOPMed
CA343171370 rs1254015041	8	I>T		No	ClinGen TOPMed gnomAD
rs138281959 CA32523860	9	G>R		No	ClinGen ESP TOPMed
CA1241904 rs746606362	10	A>G		No	ClinGen ExAC TOPMed gnomAD
rs770560362 CA1241905	11	G>A		No	ClinGen ExAC gnomAD
rs759456397 CA1241907	13	S>T		No	ClinGen ExAC gnomAD
TCGA novel	16	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs769820517 CA1241909 COSM229436	17	S>F	skin [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA343171526 rs1571389189	18	I>L		No	ClinGen Ensembl
CA343171555 rs1257072822	19	K>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs775526269 CA1241910	19	K>Q		No	ClinGen ExAC gnomAD
CA1241911 rs139357044	20	C>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA32523919 rs60906481	21	C>R		No	ClinGen Ensembl
rs983701724 CA343171601 CA32523941	22	V>L		No	ClinGen TOPMed
rs983701724 CA343171598	22	V>M		No	ClinGen TOPMed
CA343171629 rs1473133232 CA343171626	23	D>E		No	ClinGen TOPMed gnomAD
CA1241912 rs764173028	23	D>G		No	ClinGen ExAC gnomAD
TCGA novel	23	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1241913 CA1241914 rs751595529	24	E>D		No	ClinGen ExAC TOPMed gnomAD
CA32523993 VAR_084652 rs866374389	28	P>H	found in a patient with intellectual disability; unknown pathological significance [UniProt]	No	ClinGen UniProt Ensembl dbSNP
rs908136828 CA32523996	29	T>P		No	ClinGen TOPMed
rs1438448977 COSM349848 CA343171839	33	R>K	lung [Cosmic]	No	ClinGen cosmic curated TOPMed
rs767782831 CA1241916	34	S>T		No	ClinGen ExAC gnomAD
CA1241917 rs750763602	35	D>N		No	ClinGen ExAC gnomAD
CA343171883 rs1374387779	36	D>N		No	ClinGen TOPMed gnomAD
rs1374387779 CA343171888	36	D>Y		No	ClinGen TOPMed gnomAD
CA1241918 VAR_015367 rs72549338	37	I>T		No	ClinGen UniProt ESP ExAC TOPMed dbSNP gnomAD
rs150752522 CA1241919 CA343171912	38	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1241920 rs200385793	39	G>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs144010968 CA1241922	39	G>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA1241921 rs200385793	39	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	41	W>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343171961 rs1214868616	41	W>R		No	ClinGen Ensembl
CA1241923 rs746562406	42	K>*		No	ClinGen ExAC TOPMed gnomAD
rs529712306 CA1241924	44	T>S		No	ClinGen 1000Genomes ExAC gnomAD
CA343172004 rs1484577525	45	E>K		No	ClinGen gnomAD
CA343172047 rs1187438257	49	D>N		No	ClinGen gnomAD
rs1248531863 CA343172061	50	G>R		No	ClinGen gnomAD
rs1264718740 CA343172073	51	M>K		No	ClinGen TOPMed
CA343172083 rs1257488704 COSM239893	52	T>A	prostate [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA343172084 rs1257488704	52	T>S		No	ClinGen TOPMed gnomAD
rs141118786 CA1241949	54	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs1553252107 CA1241951	55	Y>*		No	ClinGen Ensembl
rs768614015 CA1241950	55	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs1228959558 CA343172124	55	Y>H		No	ClinGen TOPMed
rs1320023124 CA343172240	59	V>A		No	ClinGen gnomAD
CA343172234 rs1320023124	59	V>E		No	ClinGen gnomAD
TCGA novel	62	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1437827687 CA343172303	62	V>I		No	ClinGen gnomAD
rs760882834 CA1241957	64	K>E		No	ClinGen ExAC gnomAD
rs1326683417 TCGA novel CA343172404	66	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen gnomAD NCI-TCGA
CA1241958 rs766650072	66	M>V		No	ClinGen ExAC gnomAD
CA1241960 rs759860288	73	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA343172575 CA1241963 rs375743555	75	H>Q		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	75	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1241961 rs765668600	75	H>Y		No	ClinGen ExAC TOPMed gnomAD
COSM3418325 CA1241964 rs764211255	76	E>K	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA1241965 rs750017217	78	Y>C		No	ClinGen ExAC gnomAD
CA343172684 rs1183429707	82	M>L		No	ClinGen gnomAD
rs755813731 CA1241966	84	H>D		No	ClinGen ExAC gnomAD
CA1241967 rs779621214	84	H>L		No	ClinGen ExAC TOPMed gnomAD
CA343172728 rs779621214	84	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1170087660 CA343172746	85	E>*		No	ClinGen TOPMed
rs1471852091 CA343172777	86	K>E		No	ClinGen TOPMed
CA343172785 rs1367921023	86	K>T		No	ClinGen TOPMed
TCGA novel	87	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1241969 rs754687832	88	W>G		No	ClinGen ExAC TOPMed gnomAD
rs914285583 CA32527345	89	D>E		No	ClinGen TOPMed gnomAD
rs970683537 CA32527341	89	D>N		No	ClinGen Ensembl
rs1340449588 CA343172875	90	Y>C		No	ClinGen gnomAD
rs1420791339 CA343172971	95	A>T		No	ClinGen gnomAD
CA1241971 rs369206560	95	A>V		No	ClinGen ESP ExAC gnomAD
COSM26342 CA343172997 rs1227337681	97	H>N	kidney [Cosmic]	No	ClinGen cosmic curated gnomAD
CA343173019 rs1165541553	98	F>S		No	ClinGen gnomAD
COSM1295478 rs1244787278 CA343173032	99	D>H	Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA343173054 rs1196521742	100	L>H		No	ClinGen TOPMed
rs372532398 CA1241974	103	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA1241976 rs776681630	104	I>T		No	ClinGen ExAC gnomAD
rs1456363260 CA343173231	107	K>T		No	ClinGen gnomAD
CA1241992 rs746984414	108	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs770871064 CA1241993	109	T>S		No	ClinGen ExAC gnomAD
CA343173375 rs1486419438	110	V>E		No	ClinGen gnomAD
rs781342399 CA1241994	111	C>W		No	ClinGen ExAC TOPMed gnomAD
CA32528250 rs374521853	112	S>C		No	ClinGen ESP TOPMed
CA32528252 rs919125756	113	I>T		No	ClinGen TOPMed
CA1241995 rs746006424	113	I>V		No	ClinGen ExAC gnomAD
rs770117618 CA1241996 COSM530562	114	T>M	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA1241998 rs148886711	115	K>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs72549339 CA1242000	116	R>C		No	ClinGen ExAC TOPMed gnomAD
rs72549339 CA343173409	116	R>G		No	ClinGen ExAC TOPMed gnomAD
rs762403469 CA1242001	116	R>H		No	ClinGen ExAC TOPMed gnomAD
rs72549339 CA1241999	116	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1276577349 CA343173423	118	D>E		No	ClinGen gnomAD
rs376891289 CA1242002	118	D>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA343173425 rs1453855589	119	F>I		No	ClinGen TOPMed
CA343173438 rs1354007500	120	S>F		No	ClinGen TOPMed gnomAD
CA343173436 rs1354007500	120	S>Y		No	ClinGen TOPMed gnomAD
rs1266983673 CA343173441	121	E>A		No	ClinGen gnomAD
rs142319717 CA1242004	121	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA1242006 rs368144728	122	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs560646416 CA343173454	123	G>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA343173452 rs1246695775	123	G>C		No	ClinGen gnomAD
rs560646416 CA1242007	123	G>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs758152278 CA343173482	127	V>F		No	ClinGen ExAC TOPMed gnomAD
rs758152278 CA1242008	127	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	130	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242009 COSM3802836 rs777570552	131	T>A	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA32528367 rs944061460	131	T>K		No	ClinGen TOPMed gnomAD
rs952652080 CA32528372	132	E>D		No	ClinGen gnomAD
rs751444772 CA1242010	133	G>S		No	ClinGen ExAC TOPMed gnomAD
rs527933354 CA1242011	135	Q>K		No	ClinGen 1000Genomes ExAC gnomAD
rs146361391 CA1242012	135	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1242013 rs746015058	137	R>K		No	ClinGen ExAC gnomAD
TCGA novel	137	R>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1338446961 CA343173555 COSM677185	138	A>V	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs769883122 CA1242014	139	V>I		No	ClinGen ExAC gnomAD
CA343173561 rs1558036803	140	F>V		No	ClinGen Ensembl
rs1215631772 CA343173574	141	D>E		No	ClinGen gnomAD
rs780461281 CA1242015	141	D>G		No	ClinGen ExAC TOPMed gnomAD
CA32528430 rs199648085	146	C>Y		No	ClinGen Ensembl
rs927128151 CA32528434	147	T>A		No	ClinGen Ensembl
rs1189727804 CA343173624	149	H>P		No	ClinGen gnomAD
CA343173621 rs1464513369	149	H>Y		No	ClinGen gnomAD
CA343173631 rs1264506245	150	F>V		No	ClinGen gnomAD
TCGA novel	152	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343173653 rs1558036887	153	P>L		No	ClinGen Ensembl
rs1187331968 CA343173652	153	P>S		No	ClinGen TOPMed gnomAD
CA1242018 rs774861543	154	H>Q		No	ClinGen ExAC gnomAD
rs769093149 CA1242017	154	H>Y		No	ClinGen ExAC gnomAD
CA343173681 rs549051004	156	P>H		No	ClinGen 1000Genomes ExAC gnomAD
CA1242019 rs549051004	156	P>R		No	ClinGen 1000Genomes ExAC gnomAD
rs772696218 CA1242020	159	A>D		No	ClinGen ExAC TOPMed gnomAD
CA343173727 rs1395210968	160	F>S		No	ClinGen gnomAD
rs538568056 CA1242039	162	G>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	164	H>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs368598997 CA1242040	164	H>R		No	ClinGen ESP ExAC gnomAD
rs932694481 CA32534942	171	L>P		No	ClinGen TOPMed
TCGA novel	172	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343175087 rs1244677843	172	H>R		No	ClinGen TOPMed
rs747496222 CA1242041	172	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA32534953 rs867850762	173	S>N		No	ClinGen Ensembl
TCGA novel	175	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA32534957 rs904483581	175	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA343175188 rs1571405106	177	K>E		No	ClinGen Ensembl
CA1242042 rs769240880	179	P>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	179	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	180	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343175266 rs1299134308	181	G>S		No	ClinGen TOPMed
CA1242044 rs774988951	181	G>V		No	ClinGen ExAC TOPMed gnomAD
rs763791320 CA1242046	182	F>Y		No	ClinGen ExAC gnomAD
rs553652535 CA1242047	183	Q>H		No	ClinGen 1000Genomes ExAC gnomAD
CA1242049 rs767244751 COSM1336201	186	R>C	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA32534993 rs752631143	186	R>H		No	ClinGen TOPMed gnomAD
rs200809129 CA1242050	187	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1242051 rs755024785	188	L>*		No	ClinGen ExAC TOPMed gnomAD
CA1242052 rs368666375	188	L>F		No	ClinGen ESP ExAC gnomAD
rs1370171768 CA343175402	189	V>M		No	ClinGen gnomAD
rs1300116587 CA343175453	192	L>I		No	ClinGen gnomAD
CA1242054 rs201591723	195	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA32535015 rs781456535	196	G>R		No	ClinGen Ensembl
rs557299834 CA1242056	199	I>T		No	ClinGen ExAC TOPMed gnomAD
CA343175606 rs1226645136	199	I>V		No	ClinGen gnomAD
CA1242057 rs758743495	201	V>L		No	ClinGen ExAC TOPMed gnomAD
CA343175677 rs1221664364	203	L>F		No	ClinGen TOPMed
rs1244655500 CA343175687	204	S>G		No	ClinGen gnomAD
CA1242058 rs150913971	204	S>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA1242060 rs373804650 COSM207912	205	R>*	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs138259447 CA1242061	205	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs574075361 CA1242062	206	T>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1558040789 CA343175782	209	Q>P		No	ClinGen Ensembl
rs1558040789 CA343175785	209	Q>R		No	ClinGen Ensembl
CA1242086 rs770882505	210	V>L		No	ClinGen ExAC TOPMed gnomAD
CA343175932 rs1448734992	213	S>C		No	ClinGen TOPMed gnomAD
CA343175929 rs1448734992	213	S>R		No	ClinGen TOPMed gnomAD
CA1242088 rs145946675	214	T>I		No	ClinGen ESP ExAC gnomAD
CA1242089 rs148682062	217	G>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs763219496 CA1242091	220	V>A		No	ClinGen ExAC gnomAD
RCV000891445 rs61747501 CA1242092	221	L>H		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs376908107 CA1242093	222	G>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs376908107 CA343176096	222	G>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA1242094 rs147680748	223	R>C	Variant assessed as Somatic; 4.621e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA gnomAD
rs190463354 CA1242095	223	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA343176112 rs1358907730	224	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	227	W>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	228	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1314307362 CA343176149	228	G>S		No	ClinGen gnomAD
TCGA novel	229	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343176159 rs1348284222	229	Y>H		No	ClinGen gnomAD
rs1352236197 CA343176222	233	M>I		No	ClinGen gnomAD
rs1279687796 CA343176212	233	M>V		No	ClinGen gnomAD
CA32535993 rs886598373	234	M>I		No	ClinGen Ensembl
rs1217343698 CA343176240	235	V>F		No	ClinGen gnomAD
rs1485850069 CA343176292	239	C>Y		No	ClinGen TOPMed gnomAD
rs532183323 CA1242097	240	C>R		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	242	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1259866933 CA343176385	244	A>V		No	ClinGen gnomAD
rs202193153 CA1242098	245	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1181374943 CA343176406	246	V>L		No	ClinGen gnomAD
rs747660192 CA1242100	247	L>V		No	ClinGen ExAC TOPMed gnomAD
rs777252508 CA1242101	248	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA1242102 rs200263204	250	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs770794489 CA1242103	250	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA1242104 rs770794489	250	R>P		No	ClinGen ExAC TOPMed gnomAD
rs1175995926 CA343176516	253	N>S		No	ClinGen gnomAD
CA1242106 rs769682113	255	I>M		No	ClinGen ExAC gnomAD
TCGA novel	264	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs775613281 CA1242108	265	N>K		No	ClinGen ExAC gnomAD
CA32536108 rs1013093924	266	H>Q		No	ClinGen Ensembl
rs61753345 CA32536106	266	H>Y		No	ClinGen Ensembl
CA1242110 rs559561190	267	E>D		No	ClinGen 1000Genomes ExAC gnomAD
CA343177129 rs1268871901	274	T>S		No	ClinGen TOPMed
CA1242113 rs762035221	275	K>N		No	ClinGen ExAC gnomAD
CA343177733 rs1274637242	277	K>E		No	ClinGen gnomAD
CA1242126 rs781125343	280	K>I		No	ClinGen ExAC TOPMed gnomAD
rs1011072210 CA32537411	281	F>L		No	ClinGen TOPMed
CA32537419 rs956960816	282	I>F		No	ClinGen Ensembl
CA343177824 rs1341812378	282	I>T		No	ClinGen TOPMed gnomAD
CA343177870 rs769736989	285	D>H		No	ClinGen ExAC TOPMed gnomAD
rs769736989 COSM123200 CA1242128	285	D>N	upper_aerodigestive_tract [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1272564450 CA343177906	287	L>M		No	ClinGen gnomAD
rs775247461 CA1242129	288	P>S		No	ClinGen ExAC gnomAD
rs1246755064 CA343177951	289	N>D		No	ClinGen gnomAD
rs537208861 CA1242130	292	L>F		No	ClinGen 1000Genomes ExAC
CA343178021 rs1166270928	292	L>P		No	ClinGen TOPMed
rs1428271188 CA343178045	294	G>R		No	ClinGen gnomAD
CA32537435 rs867902199	295	A>T		No	ClinGen Ensembl
CA343178085 rs768559319	296	I>N		No	ClinGen ExAC gnomAD
CA1242131 rs768559319	296	I>T		No	ClinGen ExAC gnomAD
CA1242134 rs767784790	298	M>I		No	ClinGen ExAC gnomAD
rs762017210 CA1242133	298	M>T		No	ClinGen ExAC gnomAD
rs774417198 CA1242132	298	M>V		No	ClinGen ExAC TOPMed gnomAD
CA343178129 rs773536271	299	K>*		No	ClinGen ExAC TOPMed gnomAD
CA1242135 rs773536271	299	K>E		No	ClinGen ExAC TOPMed gnomAD
CA32537483 rs981838876	300	T>A		No	ClinGen TOPMed gnomAD
CA32537498 rs756978964	301	S>R		No	ClinGen ExAC TOPMed gnomAD
rs573059844 COSM1336205 CA1242137	302	V>M	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs142455994 CA32537527	303	I>M		No	ClinGen ESP
CA1242138 rs754244016	303	I>T		No	ClinGen ExAC gnomAD
rs1022438335 CA32537532	304	E>K		No	ClinGen TOPMed gnomAD
rs1022438335 CA343178209	304	E>Q		No	ClinGen TOPMed gnomAD
TCGA novel	305	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242139 rs3737925 VAR_049090	308	T>S		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
rs1215691181 CA343178332	311	V>I		No	ClinGen gnomAD
CA343178352 rs1204618287	312	F>S		No	ClinGen TOPMed
CA343178375 rs1483501462	314	D>G		No	ClinGen TOPMed
rs1266750254 CA343178373	314	D>Y		No	ClinGen gnomAD
rs1485867043 CA343178404	316	T>I		No	ClinGen TOPMed gnomAD
CA343178431 rs1264214531	317	V>A		No	ClinGen TOPMed gnomAD
TCGA novel	317	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751176716 CA1242141	318	E>K		No	ClinGen ExAC gnomAD
rs756951706 CA1242142	319	E>K		No	ClinGen ExAC TOPMed gnomAD
CA343178473 rs1197814521	320	N>Y		No	ClinGen gnomAD
CA343178491 rs1244791411	321	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs139018321 CA1242144	322	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs781027440 CA1242143	322	D>N		No	ClinGen ExAC gnomAD
rs1042767 VAR_015368 CA1242147	323	V>A		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA1242146 rs779909399	323	V>I		No	ClinGen ExAC TOPMed gnomAD
CA1242148 rs768646263	327	T>S		No	ClinGen ExAC TOPMed gnomAD
rs774400664 CA1242149	331	T>A		No	ClinGen ExAC gnomAD
rs748266769 COSM207913 CA1242150	333	S>Y	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1356385554 CA343178702	334	F>S		No	ClinGen gnomAD
TCGA novel	337	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1286598085 CA343178832	339	E>D		No	ClinGen gnomAD
CA1242151 rs61342270 VAR_015369	339	E>Q		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs773375083 CA1242152	340	P>R		No	ClinGen ExAC gnomAD
CA1242154 rs771136767	341	L>I		No	ClinGen ExAC TOPMed gnomAD
rs1474061718 CA343178930	343	S>N		No	ClinGen TOPMed
rs931705009 CA32537595	344	L>P		No	ClinGen Ensembl
rs545819580 CA32537597	345	C>F		No	ClinGen Ensembl
rs1263035771 CA343178947	345	C>R		No	ClinGen TOPMed gnomAD
rs1254204856 CA343179076	349	I>R		No	ClinGen TOPMed
rs759950250 CA1242157	349	I>V		No	ClinGen ExAC TOPMed
rs369627919 CA343179084	350	F>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs369627919 CA1242158	350	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	351	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242160 rs761364294	353	K>T		No	ClinGen ExAC gnomAD
TCGA novel	354	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1432420783 CA343179166	355	V>A		No	ClinGen gnomAD
TCGA novel	355	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242161 rs767155472	356	F>S		No	ClinGen ExAC gnomAD
TCGA novel	358	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749983842 CA1242162	359	N>Y		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	362	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs144578261 CA1242164	363	A>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144578261 CA1242163	363	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA343179295 rs1376280513	365	L>I		No	ClinGen gnomAD
rs147618632 COSM3735943 CA1242166	366	A>P	skin [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA1242167 rs200142632	368	I>S		No	ClinGen 1000Genomes ExAC gnomAD
rs747190267 CA1242171	369	G>D		No	ClinGen ExAC gnomAD
CA1242169 rs144698111	369	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144698111 CA1242170	369	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_022305 CA1242173 rs45599742 RCV000969927	372	G>S		No	ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs770318102 CA1242175	374	K>*		No	ClinGen ExAC
rs1350510661 CA343179414	375	G>R		No	ClinGen gnomAD
rs776094653 CA1242176	377	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1387060828 CA343179450	377	I>N		No	ClinGen TOPMed
CA343179488 rs1477621968	380	G>D		No	ClinGen TOPMed gnomAD
rs1011605442 CA32537749	380	G>S		No	ClinGen TOPMed gnomAD
CA1242177 rs763571421	382	E>Q		No	ClinGen ExAC gnomAD
CA1242178 rs767071769	385	A>V		No	ClinGen ExAC TOPMed gnomAD
CA1242179 rs373453446	386	R>*		No	ClinGen ESP ExAC gnomAD
rs201465482 CA1242180	386	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1427601789 CA343179583	387	W>C		No	ClinGen gnomAD
CA343179575 rs1396615524	387	W>L		No	ClinGen gnomAD
rs1247571550 CA343179620	389	T>I		No	ClinGen TOPMed
rs754718059 CA1242183	390	R>G		No	ClinGen ExAC gnomAD
CA343179633 rs1463635495	390	R>S		No	ClinGen TOPMed
CA32537845 rs1003206756	391	V>I		No	ClinGen TOPMed
rs1003206756 CA343179637	391	V>L		No	ClinGen TOPMed
CA1242184 rs778691681	392	F>C		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	396	C>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343180340 rs1274967720	397	K>Q		No	ClinGen gnomAD
rs1222099767 CA343180399	398	I>M		No	ClinGen TOPMed
rs1214996948 CA343180390	398	I>T		No	ClinGen gnomAD
CA343180381 rs1463532189	398	I>V		No	ClinGen gnomAD
CA343180436 rs1242416034	399	P>L		No	ClinGen gnomAD
rs1372712616 CA343180450	400	P>S		No	ClinGen TOPMed
CA1242208 rs751478744	402	Q>P		No	ClinGen ExAC gnomAD
CA1242211 rs746024147	405	M>T		No	ClinGen ExAC gnomAD
rs1447416243 COSM424587 CA343180750	407	E>Q	Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA1242212 rs144924333	408	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1460763438 CA343180845	409	T>S		No	ClinGen TOPMed
CA1242213 rs780555012	413	Q>*		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	414	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242214 rs749720900	416	K>T		No	ClinGen ExAC gnomAD
CA1242234 rs530035886	418	G>R		No	ClinGen 1000Genomes ExAC
rs74607987 CA1242235 RCV000898213	421	K>Q		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs755311415 CA1242236	421	K>R		No	ClinGen ExAC gnomAD
CA1242237 rs779150155	423	T>S		No	ClinGen ExAC gnomAD
CA1242239 rs776355579	424	S>R		No	ClinGen ExAC TOPMed gnomAD
CA1242240 rs780656682	425	K>N		No	ClinGen ExAC gnomAD
TCGA novel	427	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242241 rs745420090	429	D>G		No	ClinGen ExAC gnomAD
rs1300006451 CA343182839	431	I>L		No	ClinGen TOPMed
rs1363658220 CA343182938	433	Y>C		No	ClinGen TOPMed
CA1242245 rs768434431	434	M>I		No	ClinGen ExAC gnomAD
rs762531063 CA1242244	434	M>T		No	ClinGen ExAC gnomAD
CA1242246 rs774083463	435	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA1242248 rs145091548	438	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1242250 rs760797954	442	G>A		No	ClinGen ExAC TOPMed gnomAD
rs1314406490 CA343183331	444	K>N		No	ClinGen gnomAD
CA343183343 rs1195454309	445	P>A		No	ClinGen gnomAD
CA1242251 rs571605691	449	L>F		No	ClinGen 1000Genomes ExAC gnomAD
rs571605691 CA1242252	449	L>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1459168057 CA343183470	450	L>P		No	ClinGen gnomAD
CA343183475 rs779320943	451	F>I		No	ClinGen ExAC gnomAD
CA1242254 rs779320943	451	F>L		No	ClinGen ExAC gnomAD
CA1242255 rs753049557	451	F>S		No	ClinGen ExAC TOPMed gnomAD
CA1242256 rs758903695	452	L>V		No	ClinGen ExAC gnomAD
TCGA novel	453	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM1689175 rs778209085 CA1242257	454	D>N	skin [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs780188433 CA32542602	454	D>V		No	ClinGen TOPMed gnomAD
CA1242258 rs747532713	456	R>G		No	ClinGen ExAC gnomAD
rs779547888 CA1242261	460	E>A		No	ClinGen ExAC TOPMed gnomAD
CA32542617 rs1010631517	460	E>K		No	ClinGen TOPMed gnomAD
CA343183809 rs1223604092	462	F>L		No	ClinGen TOPMed
rs144673669 CA1242263	463	F>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA343183913 rs1226918515	464	G>E		No	ClinGen gnomAD
rs1231575314 CA343183961	466	C>F		No	ClinGen TOPMed gnomAD
rs1320065800 CA343183952	466	C>R		No	ClinGen TOPMed gnomAD
rs1231575314 CA343183970	466	C>Y		No	ClinGen TOPMed gnomAD
CA343184024 rs1273103273	467	T>I		No	ClinGen gnomAD
TCGA novel	467	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242264 rs774175010	468	P>L		No	ClinGen ExAC gnomAD
CA1242266 rs371939085	472	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs148222001 CA1242267	472	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1242268 rs760692543	474	M>T		No	ClinGen ExAC gnomAD
CA1242269 rs150724060	476	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA1242270 rs753922065	477	G>A		No	ClinGen ExAC gnomAD
rs761585310 CA32542665	479	W>*		No	ClinGen Ensembl
CA343184273 rs1425283648	479	W>R		No	ClinGen TOPMed
rs1487980598 CA343184306	480	D>H		No	ClinGen Ensembl
rs759781175 CA1242271	481	G>R		No	ClinGen ExAC gnomAD
TCGA novel	486	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343184464 rs1156771770	488	T>N		No	ClinGen gnomAD
TCGA novel	490	W>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1242272 rs765415005	490	W>R		No	ClinGen ExAC TOPMed gnomAD
CA1242273 rs143713856	492	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA343184572 rs1342687646	493	T>A		No	ClinGen TOPMed gnomAD
CA1242274 rs758709702	493	T>I		No	ClinGen ExAC TOPMed gnomAD
rs764452020 CA1242276	494	L>S		No	ClinGen ExAC gnomAD
rs764452020 CA1242275	494	L>W		No	ClinGen ExAC gnomAD
rs375299942 CA1242277	496	P>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs1571418663 CA343184763	499	T>P		No	ClinGen Ensembl
CA1242279 rs145740321	500	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs748800692 CA343184794	500	R>L		No	ClinGen ExAC TOPMed gnomAD
CA1242280 COSM207914 rs748800692	500	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA343184800 rs1206138640	501	I>T		No	ClinGen gnomAD
CA343184820 rs1571418703	502	V>A		No	ClinGen Ensembl
TCGA novel	502	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs547773096 CA1242281	504	D>G		No	ClinGen 1000Genomes ExAC gnomAD
CA343184862 rs1264858587	504	D>H		No	ClinGen gnomAD
CA343184881 rs1186784868	505	S>C		No	ClinGen gnomAD
CA343184876 rs1571418726	505	S>P		No	ClinGen Ensembl
CA32542733 rs909729685	506	S>F		No	ClinGen TOPMed gnomAD
CA1242283 rs747858852	511	M>R		No	ClinGen ExAC gnomAD
TCGA novel	511	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs963535946 CA32542743	513	H>R		No	ClinGen gnomAD
CA1242284 rs149704605	515	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA343185067 rs773207586	517	A>P		No	ClinGen ExAC TOPMed
CA1242286 rs773207586	517	A>T		No	ClinGen ExAC TOPMed
CA343185078 rs1160297459	517	A>V		No	ClinGen gnomAD
CA1242289 rs369590128	518	W>*		No	ClinGen 1000Genomes ESP ExAC gnomAD
rs1284055613 CA343185081	518	W>G		No	ClinGen TOPMed
CA343185084 rs746928621	518	W>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1284055613 CA343185080	518	W>R		No	ClinGen TOPMed
rs746928621 CA1242288	518	W>S		No	ClinGen ExAC gnomAD
rs770011693	520	A>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs772753816 CA343185110	520	A>S		No	ClinGen ExAC TOPMed gnomAD
rs772753816 CA1242290	520	A>T		No	ClinGen ExAC TOPMed gnomAD
CA1242291 rs759492132	520	A>V		No	ClinGen ExAC gnomAD
rs1397913954 CA343185120	521	P>S		No	ClinGen gnomAD
rs1315905234 COSM239894 CA343185148	522	V>F	prostate [Cosmic]	No	ClinGen cosmic curated TOPMed
TCGA novel	523	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs775513653 CA343185185	525	A>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs775513653 CA1242293	525	A>T		No	ClinGen ExAC gnomAD
rs569945058 CA32542822	526	S>A		No	ClinGen 1000Genomes gnomAD
CA343185196 rs1209645186	526	S>F		No	ClinGen gnomAD
CA343185224 rs1175040665	528	L>P		No	ClinGen gnomAD
rs1483928943 CA343185221	528	L>V		No	ClinGen gnomAD
CA1242296 rs751981160	530	I>F		No	ClinGen ExAC gnomAD
CA343185277 rs1180438107	533	S>P		No	ClinGen gnomAD
CA32542871 rs979718811	534	S>*		No	ClinGen TOPMed gnomAD
CA343185291 rs979718811	534	S>L		No	ClinGen TOPMed gnomAD
RCV000961323 CA1242297 rs75661671	534	S>P		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs45487792 CA1242298 VAR_022306	536	F>L		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
rs1398072927 CA343185315	536	F>L		No	ClinGen gnomAD
rs1173227293 CA343185321	537	L>*		No	ClinGen gnomAD
rs750972952 CA1242299	541	R>S		No	ClinGen ExAC
CA343185358 rs1360011832	541	R>T		No	ClinGen gnomAD
rs148854023 CA1242301	542	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA343185362 rs1466048320	542	D>H		No	ClinGen TOPMed gnomAD
rs1296461722 CA343185371	543	K>T		No	ClinGen gnomAD
rs45528740 VAR_022307 CA32542949	544	L>R		No	ClinGen UniProt TOPMed dbSNP
CA1242302 rs747797120	548	M>I		No	ClinGen ExAC gnomAD
CA32542953 rs938589120	548	M>R		No	ClinGen Ensembl
rs758181610 CA1242303	549	S>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA1242306 rs200262164	553	V>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1201982453 CA343185442	554	S>N		No	ClinGen TOPMed
TCGA novel	555	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1323144332 CA343185454	556	W>R		No	ClinGen TOPMed
rs776381577 CA1242307	557	R>*		No	ClinGen ExAC TOPMed gnomAD
CA1242308 rs745827392	557	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1346965744 CA343185473	559	G>R		No	ClinGen TOPMed

No associated diseases with P31512

No regional properties for P31512

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for P31512

Functions

		Description
EC Number
Subcellular Localization	Microsome membrane ; Single-pass membrane protein Endoplasmic reticulum membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

2 GO annotations of cellular component

Name	Definition
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name	Definition
flavin adenine dinucleotide binding	Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
monooxygenase activity	Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
N,N-dimethylaniline monooxygenase activity	Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
NADP binding	Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.

3 GO annotations of biological process

Name	Definition
energy homeostasis	Any process involved in the balance between food intake (energy input) and energy expenditure.
negative regulation of fatty acid oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.
xenobiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.

12 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P49326	FMO5	Flavin-containing monooxygenase 5	Homo sapiens (Human)	PR
P97501	Fmo3	Dimethylaniline monooxygenase [N-oxide-forming] 3	Mus musculus (Mouse)	PR
Q8K2I3	Fmo2	Dimethylaniline monooxygenase [N-oxide-forming] 2	Mus musculus (Mouse)	PR
P97872	Fmo5	Flavin-containing monooxygenase 5	Mus musculus (Mouse)	PR
Q8VHG0	Fmo4	Dimethylaniline monooxygenase [N-oxide-forming] 4	Mus musculus (Mouse)	PR
Q6IRI9	Fmo2	Dimethylaniline monooxygenase [N-oxide-forming] 2	Rattus norvegicus (Rat)	PR
Q9EQ76	Fmo3	Dimethylaniline monooxygenase [N-oxide-forming] 3	Rattus norvegicus (Rat)	PR
Q8K4C0	Fmo5	Flavin-containing monooxygenase 5	Rattus norvegicus (Rat)	PR
Q8K4B7	Fmo4	Dimethylaniline monooxygenase [N-oxide-forming] 4	Rattus norvegicus (Rat)	PR
Q9SVU0	YUC8	Probable indole-3-pyruvate monooxygenase YUCCA8	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SXD9	At1g62580	Flavin-containing monooxygenase FMO GS-OX-like 7	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9C8T8	At1g63340	Putative flavin-containing monooxygenase FMO GS-OX-like 10	Arabidopsis thaliana (Mouse-ear cress)	PR

10	20	30	40	50	60
MAKKVAVIGA	GVSGLSSIKC	CVDEDLEPTC	FERSDDIGGL	WKFTESSKDG	MTRVYKSLVT
70	80	90	100	110	120
NVCKEMSCYS	DFPFHEDYPN	FMNHEKFWDY	LQEFAEHFDL	LKYIQFKTTV	CSITKRPDFS
130	140	150	160	170	180
ETGQWDVVTE	TEGKQNRAVF	DAVMVCTGHF	LNPHLPLEAF	PGIHKFKGQI	LHSQEYKIPE
190	200	210	220	230	240
GFQGKRVLVI	GLGNTGGDIA	VELSRTAAQV	LLSTRTGTWV	LGRSSDWGYP	YNMMVTRRCC
250	260	270	280	290	300
SFIAQVLPSR	FLNWIQERKL	NKRFNHEDYG	LSITKGKKAK	FIVNDELPNC	ILCGAITMKT
310	320	330	340	350	360
SVIEFTETSA	VFEDGTVEEN	IDVVIFTTGY	TFSFPFFEEP	LKSLCTKKIF	LYKQVFPLNL
370	380	390	400	410	420
ERATLAIIGL	IGLKGSILSG	TELQARWVTR	VFKGLCKIPP	SQKLMMEATE	KEQLIKRGVF
430	440	450	460	470	480
KDTSKDKFDY	IAYMDDIAAC	IGTKPSIPLL	FLKDPRLAWE	VFFGPCTPYQ	YRLMGPGKWD
490	500	510	520	530	540
GARNAILTQW	DRTLKPLKTR	IVPDSSKPAS	MSHYLKAWGA	PVLLASLLLI	CKSSLFLKLV
550
RDKLQDRMSP	YLVSLWRG