Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SGD2

Entry ID Method Resolution Chain Position Source
AF-Q9SGD2-F1 Predicted AlphaFoldDB

22 variants for Q9SGD2

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH04538652 4 S>P No 1000Genomes
ENSVATH04538654 19 A>T No 1000Genomes
ENSVATH04538656 43 S>T No 1000Genomes
tmp_1_2608544_T_G 46 L>R No 1000Genomes
tmp_1_2608550_C_T 48 T>I No 1000Genomes
tmp_1_2608553_A_G 49 E>G No 1000Genomes
ENSVATH04538659 86 S>R No 1000Genomes
ENSVATH01024435 93 S>F No 1000Genomes
ENSVATH10780618 94 M>T No 1000Genomes
ENSVATH04538661 173 R>K No 1000Genomes
ENSVATH04538664 188 N>D No 1000Genomes
tmp_1_2608976_A_G 190 Q>R No 1000Genomes
tmp_1_2608990_A_G 195 I>V No 1000Genomes
ENSVATH10780619 209 T>I No 1000Genomes
ENSVATH04538665 238 S>G No 1000Genomes
tmp_1_2609177_C_T 257 P>L No 1000Genomes
tmp_1_2609185_G_T 260 V>F No 1000Genomes
tmp_1_2609251_G_C 282 D>H No 1000Genomes
ENSVATH00011558 295 K>E No 1000Genomes
ENSVATH00011559 295 K>R No 1000Genomes
ENSVATH04538671 305 G>R No 1000Genomes
ENSVATH00011563 378 S>N No 1000Genomes

No associated diseases with Q9SGD2

No regional properties for Q9SGD2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SGD2

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
galactosyltransferase activity Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
sialyltransferase activity Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.

1 GO annotations of biological process

Name Definition
protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

11 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q92184 ST6GALNAC2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Gallus gallus (Chicken) PR
Q92182 ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 Gallus gallus (Chicken) PR
Q701R0 ST6GAL2 Beta-galactoside alpha-2,6-sialyltransferase 2 Gallus gallus (Chicken) PR
P15907 ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 Homo sapiens (Human) PR
Q9UJ37 ST6GALNAC2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Homo sapiens (Human) PR
Q96JF0 ST6GAL2 Beta-galactoside alpha-2,6-sialyltransferase 2 Homo sapiens (Human) PR
Q9BVH7 ST6GALNAC5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Homo sapiens (Human) PR
Q64685 St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 Mus musculus (Mouse) PR
Q9QYJ1 St6galnac5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Mus musculus (Mouse) PR
P70277 St6galnac2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Mus musculus (Mouse) PR
P13721 St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKRSVRPLFS ALLFAFFAAT LICRVAIRRS SFSFASAIAE LGSSGLMTED IVFNETLLEF
70 80 90 100 110 120
AAIDPGEPNF KQEVDLISDY DHTRRSHRRH FSSMSIRPSE QQRRVSRDIA SSSKFPVTLR
130 140 150 160 170 180
SSQAYRYWSE FKRNLRLWAR RRAYEPNIML DLIRLVKNPI DVHNGVVSIS SERYLSCAVV
190 200 210 220 230 240
GNSGTLLNSQ YGDLIDKHEI VIRLNNAKTE RFEKKVGSKT NISFINSNIL HQCGRRESCY
250 260 270 280 290 300
CHPYGETVPI VMYICQPIHV LDYTLCKPSH RAPLLITDPR FDVMCARIVK YYSVKKFLEE
310 320 330 340 350 360
KKAKGFVDWS KDHEGSLFHY SSGMQAVMLA VGICEKVSVF GFGKLNSTKH HYHTNQKAEL
370 380 390
KLHDYEAEYR LYRDLENSPR AIPFLPKEFK IPLVQVYH