Q96JF0
PR
Gene name |
ST6GAL2 (KIAA1877, SIAT2) |
Protein name |
Beta-galactoside alpha-2,6-sialyltransferase 2 |
Names |
Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, hST6Gal II, Sialyltransferase 2 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:84620 |
EC number |
2.4.3.1: Sialyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q96JF0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q96JF0-F1 | Predicted | AlphaFoldDB |
536 variants for Q96JF0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA348112327 rs1161980629 |
4 | H>L | No |
ClinGen TOPMed gnomAD |
|
|
rs375816524 CA53860316 |
4 | H>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA348112330 rs1341113854 |
4 | H>Y | No |
ClinGen TOPMed |
|
|
CA348112324 rs1158339320 |
5 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1573262067 CA348112299 |
8 | W>* | No |
ClinGen Ensembl |
|
|
CA348112295 rs1251606516 |
8 | W>C | No |
ClinGen TOPMed |
|
|
CA53860315 rs911490484 |
9 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA348112288 rs1250388654 |
9 | R>S | No |
ClinGen gnomAD |
|
|
CA348112277 rs867465675 |
11 | R>L | No |
ClinGen TOPMed |
|
|
rs867465675 CA53860314 COSM164617 |
11 | R>Q | Variant assessed as Somatic; 0.0 impact. skin endometrium breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs985603049 CA53860313 |
12 | M>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs952861175 CA53860312 |
14 | F>L | No |
ClinGen gnomAD |
|
|
CA348112235 rs749318938 |
17 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53860310 rs1027038630 |
17 | F>L | No |
ClinGen Ensembl |
|
|
COSM331245 CA1817638 rs756320214 |
18 | A>S | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
COSM3390846 rs756320214 COSM84620 CA1817637 |
18 | A>T | pancreas [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA348112231 rs1558702853 |
18 | A>V | No |
ClinGen Ensembl |
|
|
CA348112222 rs1240125374 |
19 | W>* | No |
ClinGen gnomAD |
|
|
CA1817633 rs757601261 |
22 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1243788826 CA348112197 |
23 | F>L | No |
ClinGen gnomAD |
|
|
CA348112191 rs1335180034 |
24 | L>F | No |
ClinGen gnomAD |
|
|
CA1817632 rs752050814 |
24 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1397972342 CA348112189 |
25 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
CA348112170 rs1297296614 |
28 | I>V | No |
ClinGen gnomAD |
|
|
rs118018738 CA53860309 |
29 | Y>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1817631 rs118018738 |
29 | Y>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1817630 rs138857139 |
30 | F>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs62155507 CA1817629 |
30 | F>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1817627 rs760357607 |
31 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs771899592 CA1817625 |
32 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761755100 CA1817624 |
33 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs146572697 CA1817623 |
33 | S>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA53860307 rs893646973 |
37 | E>A | No |
ClinGen gnomAD |
|
|
rs893646973 CA348112110 |
37 | E>G | No |
ClinGen gnomAD |
|
|
rs371811755 CA1817620 |
39 | V>I | No |
ClinGen ESP ExAC gnomAD |
|
|
rs769811552 CA1817619 |
40 | P>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 40 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 41 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1277334297 CA348112084 |
41 | S>R | No |
ClinGen gnomAD |
|
|
rs746070116 CA1817618 |
42 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs1362202326 CA348112077 |
43 | L>I | No |
ClinGen gnomAD |
|
|
CA1817617 rs781329223 |
43 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA348112069 rs1390891314 |
44 | S>Y | No |
ClinGen gnomAD |
|
|
rs1422391663 CA348112059 |
45 | F>L | No |
ClinGen gnomAD |
|
|
rs1474242668 CA348112065 |
45 | F>L | No |
ClinGen gnomAD |
|
|
CA348112044 rs1424082837 |
48 | T>A | No |
ClinGen TOPMed |
|
|
CA53860306 rs916986264 |
50 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1451486411 CA348112026 |
51 | L>F | No |
ClinGen gnomAD |
|
|
rs145721349 CA1817612 |
52 | L>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs372148383 CA1817610 COSM569122 |
53 | P>L | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs750074911 CA348112011 |
54 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750074911 CA1817609 |
54 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817608 rs201439330 |
55 | Q>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1435703065 CA348112002 |
55 | Q>R | No |
ClinGen gnomAD |
|
|
CA348111994 rs1324964819 |
56 | G>V | No |
ClinGen gnomAD |
|
|
CA348111987 rs1398907540 |
57 | K>N | No |
ClinGen gnomAD |
|
|
CA348111993 rs1558702328 |
57 | K>Q | No |
ClinGen Ensembl |
|
|
rs1293048731 CA348111981 |
58 | Q>R | No |
ClinGen TOPMed |
|
|
rs761558561 CA1817607 |
59 | R>P | No |
ClinGen ExAC gnomAD |
|
|
rs761558561 CA348111975 |
59 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1171034466 CA348111976 |
59 | R>W | No |
ClinGen gnomAD |
|
|
CA348111965 rs1483884374 |
61 | I>F | No |
ClinGen Ensembl |
|
|
rs1483884374 CA348111966 |
61 | I>V | No |
ClinGen Ensembl |
|
|
rs774244072 CA348111960 |
62 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817606 rs774244072 |
62 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817605 rs762960856 |
64 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762960856 CA348111946 |
64 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762960856 CA1817604 |
64 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775329379 CA1817603 |
65 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA53860305 rs368418036 |
66 | H>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs943721547 CA53860304 |
67 | E>* | No |
ClinGen Ensembl |
|
|
rs781338462 COSM3379726 COSM3379727 CA1817601 |
70 | P>L | Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA1817600 rs781338462 |
70 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1237609883 CA348111906 |
71 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
rs978633880 CA53860303 |
72 | G>E | No |
ClinGen TOPMed |
|
|
rs1261057134 CA348111893 |
73 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1218362810 CA348111885 |
75 | D>N | No |
ClinGen gnomAD |
|
|
rs771103475 CA1817598 |
76 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA53860302 rs911438308 |
76 | A>V | No |
ClinGen Ensembl |
|
|
rs778092767 CA1817596 COSM1526967 |
77 | R>C | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
COSM3406755 CA348111870 rs758806051 COSM3406754 |
77 | R>H | Variant assessed as Somatic; impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs758806051 CA1817595 |
77 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs529061058 CA1817594 |
79 | A>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
COSM84619 CA1817593 rs562042019 |
79 | A>V | Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs755520550 CA1817592 |
80 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA1817589 rs756916800 |
82 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA1817590 rs756916800 |
82 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817588 rs751305558 |
82 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 82 | R>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs564025581 CA348111842 |
83 | A>D | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA53860301 rs564025581 |
83 | A>G | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs762905808 CA1817586 |
83 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA348111840 rs1183264090 |
84 | H>N | No |
ClinGen TOPMed gnomAD |
|
|
CA348111829 rs1209670004 |
85 | P>Q | No |
ClinGen gnomAD |
|
|
CA348111830 rs1235891104 |
85 | P>S | No |
ClinGen gnomAD |
|
|
rs1222025531 CA348111803 |
89 | F>C | No |
ClinGen gnomAD |
|
|
rs1264064249 CA348111799 |
90 | H>D | No |
ClinGen gnomAD |
|
|
rs80079355 CA1817581 |
91 | A>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1817580 rs80079355 COSM1564874 |
91 | A>V | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs747205074 CA1817579 |
92 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs974754581 CA53860300 |
92 | G>R | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 93 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA53860299 rs966470817 |
93 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1360160407 CA348111775 |
94 | G>A | No |
ClinGen gnomAD |
|
|
rs1360160407 CA348111776 |
94 | G>E | No |
ClinGen gnomAD |
|
|
CA53860298 rs920131957 |
95 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs920131957 CA348111772 |
95 | D>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs773493469 CA1817578 |
96 | L>M | No |
ClinGen ExAC gnomAD |
|
|
rs1352697383 CA348111760 |
97 | Q>* | No |
ClinGen TOPMed |
|
|
rs779337292 CA1817575 |
99 | W>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817576 rs748401765 |
99 | W>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 103 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1181542178 CA348111714 |
103 | Q>L | No |
ClinGen gnomAD |
|
|
CA53860295 rs950847770 |
104 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA348111706 rs1473218974 |
104 | D>V | No |
ClinGen gnomAD |
|
|
rs1314073215 CA348111702 |
105 | G>R | No |
ClinGen gnomAD |
|
|
rs749819990 CA1817573 COSM1266854 |
107 | E>K | kidney oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA1817572 rs73949785 |
109 | K>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1558701728 CA348111670 |
109 | K>N | No |
ClinGen Ensembl |
|
|
rs200701778 CA1817571 |
110 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 111 | F>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817570 rs761887652 |
112 | F>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 113 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1327855726 | 113 | S>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1319444324 CA348111646 |
113 | S>T | No |
ClinGen gnomAD |
|
|
CA1817569 rs202001830 |
114 | S>F | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA1817568 COSM3406752 rs377166692 COSM3406751 |
116 | V>M | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1181856443 CA348111616 |
118 | R>G | No |
ClinGen TOPMed |
|
|
CA53860293 rs928722382 |
118 | R>K | No |
ClinGen gnomAD |
|
|
rs752395579 CA1817567 |
120 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA348111591 rs1573260197 |
121 | Q>H | No |
ClinGen Ensembl |
|
|
rs116003024 CA1817566 |
122 | S>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1817565 rs116003024 |
122 | S>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA53860291 rs866450627 |
123 | A>T | No |
ClinGen gnomAD |
|
| TCGA novel | 124 | F>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs906132688 CA53860290 |
126 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs906132688 CA348111559 |
126 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA348111557 rs1399789087 |
127 | E>K | No |
ClinGen TOPMed |
|
|
rs1422029942 COSM140420 CA348111549 |
128 | D>N | Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA1817564 rs776674229 |
131 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1328977088 CA348111512 CA348111513 |
132 | F>L | No |
ClinGen TOPMed |
|
|
CA1817563 rs766445580 |
132 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs553645667 CA1817562 |
135 | A>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA348111492 rs1191758598 |
136 | G>C | No |
ClinGen gnomAD |
|
|
CA348111468 rs199962702 |
139 | G>A | No |
ClinGen gnomAD |
|
|
rs199962702 CA53860287 |
139 | G>E | No |
ClinGen gnomAD |
|
| TCGA novel | 139 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1442834072 CA348111470 |
139 | G>W | No |
ClinGen TOPMed |
|
|
rs773296782 CA1817561 |
140 | W>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1195819265 CA348111457 |
141 | H>Y | No |
ClinGen gnomAD |
|
|
CA1817560 rs772211728 |
142 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA348111443 rs1376317618 |
143 | H>N | No |
ClinGen TOPMed |
|
|
rs867733061 CA53860286 |
145 | Q>* | No |
ClinGen Ensembl |
|
|
CA53860285 rs568673606 |
145 | Q>P | No |
ClinGen gnomAD |
|
|
CA53860284 rs142700199 |
147 | T>A | No |
ClinGen Ensembl |
|
| TCGA novel | 147 | T>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817556 rs141100958 |
150 | F>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
rs1402428532 CA348111389 |
151 | P>L | Variant assessed as Somatic; 4.621e-05 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA53860283 rs201546993 |
151 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA1817554 rs770549355 |
153 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA1817553 rs746454620 |
153 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs746454620 CA348111379 |
153 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1465277097 CA348111377 |
154 | G>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA1817550 VAR_038046 rs3796110 CA1817552 |
154 | G>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA1817551 rs3796110 |
154 | G>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs570828111 CA1817549 |
155 | E>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA348111359 rs1172503683 |
157 | G>D | No |
ClinGen gnomAD |
|
| TCGA novel | 157 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 158 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs754872937 CA348111347 |
159 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817548 rs754872937 |
159 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754872937 CA348111348 |
159 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1260390177 COSM1266856 CA348111349 |
159 | R>W | oesophagus [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA1817546 rs766249358 |
160 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA348111344 rs1489216384 |
160 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA348111330 rs1318116034 |
162 | A>G | No |
ClinGen gnomAD |
|
|
CA1817545 rs760608485 |
162 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1188693156 CA348111315 |
164 | P>L | No |
ClinGen TOPMed |
|
|
CA348111306 rs1573259525 |
166 | A>S | No |
ClinGen Ensembl |
|
| TCGA novel | 167 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1301261571 CA348111290 |
168 | V>D | No |
ClinGen gnomAD |
|
|
CA348111292 rs1310790544 |
168 | V>F | No |
ClinGen gnomAD |
|
|
CA348111286 rs1476927983 |
169 | Q>* | No |
ClinGen TOPMed |
|
|
CA1817544 rs750460237 |
169 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1558701122 CA348111281 |
170 | R>G | No |
ClinGen Ensembl |
|
| TCGA novel | 170 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348111275 rs1373349831 |
170 | R>S | No |
ClinGen gnomAD |
|
|
CA1817542 rs76671923 |
172 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs767653102 COSM369298 CA1817543 |
172 | R>W | lung large_intestine meninges [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA348111264 rs1333135819 |
173 | V>M | No |
ClinGen gnomAD |
|
|
rs768898527 CA1817539 |
174 | K>N | No |
ClinGen ExAC |
|
|
CA1817538 rs763431064 |
176 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs537038435 CA1817537 |
176 | R>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs770385803 CA348111232 CA1817536 |
177 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs771652703 CA1817534 |
178 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771652703 CA1817533 |
178 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746401401 CA1817535 |
178 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs138095673 CA1817532 |
179 | R>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 179 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817530 rs754602069 |
180 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA1817531 rs778688597 |
180 | Q>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348111220 rs1290889701 |
180 | Q>R | No |
ClinGen gnomAD |
|
| TCGA novel | 182 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1357307343 CA348111204 |
182 | R>S | No |
ClinGen TOPMed |
|
|
rs369563349 CA53860279 |
183 | S>T | No |
ClinGen ESP TOPMed |
|
|
rs185101731 CA1817529 |
184 | H>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs779852859 CA1817528 |
185 | V>G | No |
ClinGen ExAC gnomAD |
|
|
rs889490672 CA53860278 |
185 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
| TCGA novel | 187 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs750405152 CA1817526 |
187 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1558700868 CA348111165 |
188 | E>D | No |
ClinGen Ensembl |
|
|
rs762019398 CA1817524 |
189 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348111159 rs762019398 |
189 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs142741001 CA1817523 |
190 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1309510672 CA348111158 |
190 | D>N | No |
ClinGen gnomAD |
|
|
CA348111156 rs1309510672 |
190 | D>Y | No |
ClinGen gnomAD |
|
|
CA348111145 CA1817521 rs146192357 |
191 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1401296066 CA348111150 |
191 | D>H | No |
ClinGen gnomAD |
|
|
rs1401296066 CA348111149 |
191 | D>Y | No |
ClinGen gnomAD |
|
|
CA1817520 rs143354621 |
192 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs770332400 CA348111134 |
193 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs1486908982 CA348111136 |
193 | D>G | No |
ClinGen TOPMed |
|
|
CA53860277 rs1037175427 |
193 | D>N | No |
ClinGen Ensembl |
|
|
CA53860275 rs1027754263 |
196 | Y>* | No |
ClinGen TOPMed |
|
|
rs973523102 CA53860274 |
197 | S>A | No |
ClinGen TOPMed |
|
|
CA348111110 rs528424981 |
197 | S>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs528424981 CA1817516 |
197 | S>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs747638518 CA1817513 |
199 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA348111100 rs1422827075 |
199 | M>T | No |
ClinGen gnomAD |
|
|
rs771474102 CA1817515 |
199 | M>V | No |
ClinGen ExAC |
|
|
COSM569129 CA348111093 rs1486948627 |
200 | S>F | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA1817511 rs768311561 |
200 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs768311561 CA1817512 |
200 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA1817510 rs748959361 |
201 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs755939257 CA1817508 |
202 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348111082 rs755939257 |
202 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 204 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1242916612 CA348111069 |
204 | L>Q | No |
ClinGen gnomAD |
|
|
CA348111060 rs1416447332 |
206 | R>G | No |
ClinGen gnomAD |
|
|
rs1313466416 CA348111058 |
206 | R>Q | No |
ClinGen TOPMed |
|
|
rs1416447332 CA348111059 |
206 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1338138652 CA348111041 |
208 | W>C | No |
ClinGen gnomAD |
|
|
CA348111035 rs757152539 |
209 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53860272 rs535316547 |
209 | K>R | No |
ClinGen gnomAD |
|
|
CA53860271 rs371878571 |
210 | G>A | No |
ClinGen ESP |
|
|
CA348111031 rs1319748824 |
210 | G>W | No |
ClinGen TOPMed |
|
|
rs1386522472 CA348111020 |
212 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs751589118 CA1817504 |
213 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs1573258605 CA348111008 |
214 | S>P | No |
ClinGen Ensembl |
|
|
CA1817502 rs753008259 |
216 | M>R | No |
ClinGen ExAC gnomAD |
|
|
CA1817501 rs753008259 |
216 | M>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 216 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348110987 rs1573258571 |
217 | L>V | No |
ClinGen Ensembl |
|
|
rs746949644 CA1817500 |
218 | N>T | No |
ClinGen ExAC gnomAD |
|
|
CA348110971 rs1261444571 COSM390571 |
219 | P>L | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA348110968 COSM295846 rs1193641422 |
220 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1488876821 CA348110967 |
220 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1488876821 CA348110965 |
220 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs957977016 CA53860268 |
223 | K>R | No |
ClinGen TOPMed |
|
|
rs1266325444 CA348110941 |
224 | A>V | No |
ClinGen gnomAD |
|
|
rs776878232 CA1817498 |
228 | Y>N | No |
ClinGen ExAC gnomAD |
|
|
rs1573258434 CA348110910 |
228 | Y>S | No |
ClinGen Ensembl |
|
|
rs1573258407 CA348110902 |
229 | L>R | No |
ClinGen Ensembl |
|
|
rs1277277487 CA348110905 |
229 | L>V | No |
ClinGen gnomAD |
|
|
rs141122114 CA1817497 |
230 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA348110901 rs1573258385 |
230 | T>P | No |
ClinGen Ensembl |
|
|
rs369427384 CA348110896 |
231 | A>S | No |
ClinGen ESP gnomAD |
|
|
rs369427384 CA53860266 |
231 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA gnomAD |
|
rs1390823193 CA348110889 |
232 | N>Y | No |
ClinGen gnomAD |
|
|
rs773859154 CA1817495 |
233 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs1166420396 CA348110870 |
234 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA1817492 rs775186979 |
235 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA1817493 CA1817494 rs376167669 |
235 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs530496847 CA1817491 COSM1291277 |
237 | R>C | Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA348110858 rs530496847 |
237 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA348110856 rs1430200985 |
237 | R>P | No |
ClinGen gnomAD |
|
|
rs530496847 CA348110859 |
237 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA348110844 rs1197359205 |
239 | R>C | No |
ClinGen gnomAD |
|
|
CA1817490 COSM1004960 rs371609380 |
239 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs746969361 CA1817488 COSM1398632 CA348110841 |
240 | G>R | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD NCI-TCGA |
|
rs746969361 CA1817487 |
240 | G>W | No |
ClinGen ExAC gnomAD |
|
|
CA1817486 rs777878110 |
241 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
CA1817485 rs758618457 |
242 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348110829 rs758618457 |
242 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs371937457 CA53860265 COSM404715 |
242 | R>W | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs765501707 CA1817483 |
243 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53860264 rs1008022174 |
243 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1573257977 CA348110814 TCGA novel |
245 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen Ensembl |
|
CA348110805 rs1309029685 |
246 | L>R | No |
ClinGen TOPMed |
|
|
rs911864717 CA53860263 |
248 | R>K | No |
ClinGen TOPMed |
|
|
rs1444167346 CA348110788 |
249 | A>T | No |
ClinGen gnomAD |
|
|
CA1817481 rs374874543 |
252 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 253 | C>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs929332547 CA53860261 |
253 | C>G | No |
ClinGen TOPMed gnomAD |
|
|
CA348110749 rs1410941664 |
255 | L>Q | No |
ClinGen gnomAD |
|
|
CA348110745 rs1171387380 |
256 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1422051543 CA348110746 |
256 | R>W | No |
ClinGen gnomAD |
|
|
CA1817480 rs766673161 |
257 | S>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53860260 rs898721265 |
257 | S>R | No |
ClinGen Ensembl |
|
|
CA348110735 rs1395800929 |
258 | R>C | No |
ClinGen gnomAD |
|
|
rs1456621255 CA348110722 |
260 | R>C | No |
ClinGen gnomAD |
|
|
CA348110723 rs1456621255 |
260 | R>G | No |
ClinGen gnomAD |
|
|
rs1237864919 CA348110719 |
260 | R>H | No |
ClinGen gnomAD |
|
|
CA348110720 rs1237864919 |
260 | R>P | No |
ClinGen gnomAD |
|
|
CA53860259 rs1037689676 CA348110717 |
261 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA348110718 rs1037689676 |
261 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
COSM3701912 CA348110703 rs1345582889 COSM3701911 |
263 | T>M | Variant assessed as Somatic; 0.0 impact. liver [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA53860258 rs940168599 |
264 | L>M | No |
ClinGen Ensembl |
|
|
rs773627637 CA1817478 |
264 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs763586738 CA53860257 |
266 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763586738 CA1817477 |
266 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1443893427 CA348110679 |
268 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs769367829 CA1817474 |
272 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA53860256 rs1023555976 |
273 | A>T | No |
ClinGen TOPMed |
|
|
CA348110644 rs1176063528 |
273 | A>V | No |
ClinGen gnomAD |
|
|
CA348110643 rs1407134914 |
274 | L>M | No |
ClinGen TOPMed gnomAD |
|
|
CA348110619 rs1471254288 |
277 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1178047224 COSM3390841 COSM3390840 CA348110622 |
277 | R>W | pancreas [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA1817473 rs759140364 |
278 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348110614 rs759140364 |
278 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817472 rs776466501 CA53860255 |
280 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1485968518 CA348110601 |
281 | P>H | No |
ClinGen gnomAD |
|
|
rs1485968518 CA348110599 |
281 | P>L | No |
ClinGen gnomAD |
|
|
rs770673105 CA1817471 |
282 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770673105 CA348110598 |
282 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348110594 rs1424535500 |
282 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA1817469 rs777630203 |
283 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53860253 rs990080002 |
284 | P>H | No |
ClinGen Ensembl |
|
|
CA348110588 rs1275146606 |
284 | P>T | No |
ClinGen TOPMed |
|
|
rs1225144673 CA348110575 |
286 | S>N | No |
ClinGen gnomAD |
|
|
rs1225144673 CA348110574 |
286 | S>T | No |
ClinGen gnomAD |
|
|
rs1376433010 CA348110568 |
287 | Q>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs772153522 CA1817467 |
287 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348110552 rs139995152 CA53860252 |
289 | H>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs755206333 CA348110548 |
290 | P>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755206333 CA1817464 |
290 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754052250 COSM3708793 CA1817463 COSM88681 |
291 | R>C | ovary liver [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs754052250 CA348110546 COSM1526969 |
291 | R>S | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA1817461 rs577158909 |
292 | G>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs780431339 CA1817462 |
292 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs1021383351 CA348110536 |
293 | L>M | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 293 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348110528 rs1181487739 |
294 | R>H | No |
ClinGen gnomAD |
|
| TCGA novel | 295 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1475433439 CA348110521 |
295 | S>N | No |
ClinGen gnomAD |
|
|
CA1817460 rs750925772 |
295 | S>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 297 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs762309942 CA1817458 |
299 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348110484 rs1242196059 |
301 | S>P | No |
ClinGen gnomAD |
|
|
CA1817456 rs764747941 |
304 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA348110454 rs1475327833 |
306 | L>V | No |
ClinGen TOPMed |
|
|
CA53860249 rs899630822 |
307 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1353096914 CA348110424 |
310 | L>F | No |
ClinGen TOPMed |
|
|
CA348110413 rs1402055837 |
312 | E>G | No |
ClinGen TOPMed |
|
|
CA348110417 rs1299127472 |
312 | E>K | No |
ClinGen TOPMed |
|
|
rs1335982644 CA348110408 |
313 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA348110395 rs1295449479 |
314 | I>M | No |
ClinGen gnomAD |
|
|
rs1573256945 CA348110400 |
314 | I>V | No |
ClinGen Ensembl |
|
|
rs776213215 CA1817454 |
315 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA348110355 rs1268344857 |
318 | D>E | No |
ClinGen TOPMed |
|
| TCGA novel | 318 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs139517922 CA1817436 |
319 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs773096997 CA1817434 |
321 | L>W | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 322 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348110335 rs1329544630 |
322 | R>K | No |
ClinGen gnomAD |
|
|
CA1817433 rs767472492 |
323 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 325 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817432 rs761807841 |
327 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53859187 rs931844470 |
328 | T>A | No |
ClinGen TOPMed |
|
|
CA53859186 rs774493419 |
329 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs768765330 CA1817430 |
329 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817431 rs774493419 |
329 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA348110285 rs1193642284 |
330 | G>V | No |
ClinGen gnomAD |
|
|
CA1817429 rs749266455 |
332 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA348110275 rs1473596085 |
332 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs267598827 CA53859185 |
334 | D>N | No |
ClinGen TOPMed |
|
|
COSM1004959 CA348110260 rs267598827 |
334 | D>Y | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA1817428 rs775642020 |
335 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348110254 rs1460038786 |
335 | V>I | No |
ClinGen TOPMed |
|
|
CA1817425 rs141891229 |
337 | N>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs781512929 CA1817424 |
337 | N>I | No |
ClinGen ExAC gnomAD |
|
|
CA53859184 rs1017818811 |
338 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
CA1817423 rs757686327 |
340 | T>I | No |
ClinGen ExAC gnomAD |
|
|
VAR_038047 rs12615112 CA1817422 |
341 | I>V | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs533150647 COSM3406748 COSM267515 CA1817421 |
342 | R>C | large_intestine central_nervous_system Variant assessed as Somatic; 4.622e-05 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
COSM3390839 COSM1227680 rs758951633 CA1817420 |
342 | R>H | pancreas large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
| TCGA novel | 344 | I>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs138821621 COSM200548 CA1817418 |
346 | S>L | Variant assessed as Somatic; 0.0 impact. large_intestine urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD |
|
rs1486901516 CA348110153 |
349 | L>P | No |
ClinGen gnomAD |
|
|
rs267598826 CA53859050 |
350 | T>A | No |
ClinGen Ensembl |
|
|
CA348110139 rs1261164092 |
351 | N>K | No |
ClinGen gnomAD |
|
|
rs1573236579 CA348110141 |
351 | N>T | No |
ClinGen Ensembl |
|
|
CA1817391 rs752719123 |
353 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs368477217 CA1817390 |
357 | I>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 358 | D>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA53859048 rs141033323 |
359 | S>N | No |
ClinGen ESP TOPMed |
|
|
rs759555817 CA1817389 |
359 | S>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 364 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM3379725 CA1817387 COSM3379724 rs371333085 |
365 | V>I | pancreas [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
| TCGA novel | 367 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348109995 rs1382339735 COSM1690862 |
372 | P>S | skin [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA53859046 rs1012402259 |
376 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs772530808 CA1817384 |
376 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM2981777 COSM3772391 CA1817382 rs779528340 |
377 | A>T | pancreas [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1476485529 CA348109963 |
377 | A>V | No |
ClinGen gnomAD |
|
|
rs1558690122 CA348109947 |
380 | N>H | No |
ClinGen Ensembl |
|
|
rs745306878 CA1817380 |
380 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1426270172 CA348109919 |
382 | W>* | No |
ClinGen TOPMed |
|
|
rs1474174088 CA348109895 |
385 | K>I | No |
ClinGen gnomAD |
|
|
CA348109887 rs1399324772 |
386 | P>L | Variant assessed as Somatic; 4.877e-05 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| rs1261813632 | 386 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1411040733 COSM247610 CA348109892 |
386 | P>T | prostate [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA348109886 rs1157395736 |
387 | D>N | No |
ClinGen TOPMed |
|
|
CA1817348 rs750479581 |
390 | L>M | No |
ClinGen ExAC gnomAD |
|
|
CA1817347 rs144829459 |
392 | T>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs761970876 CA1817346 |
397 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1232121779 CA348109814 |
397 | H>Y | No |
ClinGen gnomAD |
|
|
CA53858801 COSM1690861 rs865916184 |
398 | R>C | Variant assessed as Somatic; impact. skin [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
COSM236587 CA1817345 rs144935783 |
398 | R>H | Variant assessed as Somatic; 0.0 impact. autonomic_ganglia [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA1817344 rs144935783 |
398 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 400 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs370374528 CA1817343 |
401 | N>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA348109789 rs1210068130 |
401 | N>T | No |
ClinGen gnomAD |
|
| TCGA novel | 402 | P>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 402 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817342 rs202006816 |
405 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
CA348109745 rs1237507662 |
407 | Y>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA1817341 rs770438688 |
410 | H>N | No |
ClinGen ExAC gnomAD |
|
|
rs746461895 CA1817340 CA53858800 |
412 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1304601667 CA348109712 |
412 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA348109709 rs1240815104 |
413 | F>I | No |
ClinGen TOPMed |
|
|
CA1817338 rs771709463 |
414 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA348109698 rs1337901290 |
414 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs139141184 CA1817339 |
414 | I>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA53858799 rs917318306 |
417 | L>I | No |
ClinGen Ensembl |
|
|
CA348109679 rs917318306 |
417 | L>V | No |
ClinGen Ensembl |
|
|
rs1573232126 CA348109662 |
419 | D>G | No |
ClinGen Ensembl |
|
|
rs1055915782 CA348109665 |
419 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1055915782 CA53858798 |
419 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs1175555223 CA348109642 |
422 | Q>E | No |
ClinGen gnomAD |
|
|
rs747806776 CA1817337 |
423 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs747806776 CA348109635 |
423 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1558688170 CA348109620 |
425 | T>A | No |
ClinGen Ensembl |
|
|
CA1817336 rs778650793 |
425 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 425 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 428 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1305505 rs1159334068 CA348109585 |
430 | Q>K | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA1817335 rs754838335 |
431 | P>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA348109568 rs1255115078 |
432 | N>T | No |
ClinGen gnomAD |
|
|
rs1187149898 CA348109559 |
433 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1259038981 CA348109557 |
434 | P>A | No |
ClinGen gnomAD |
|
|
rs992026369 CA53858796 |
437 | G>A | No |
ClinGen TOPMed |
|
|
rs992026369 CA348109537 |
437 | G>D | No |
ClinGen TOPMed |
|
|
CA1817291 rs745813010 |
441 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1406759009 CA348109312 |
442 | L>F | No |
ClinGen TOPMed |
|
|
CA1817290 rs781048303 |
443 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs1345838434 CA348109300 |
444 | M>V | No |
ClinGen gnomAD |
|
|
CA1817288 rs567302242 |
445 | M>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1235340802 CA348109280 |
446 | S>F | No |
ClinGen gnomAD |
|
|
rs1573194983 CA348109282 |
446 | S>P | No |
ClinGen Ensembl |
|
|
CA1817286 rs758673479 |
447 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA1817287 rs139982021 |
447 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1817284 rs779333492 |
449 | R>T | No |
ClinGen ExAC gnomAD |
|
|
rs1249177719 CA348109239 |
452 | H>P | No |
ClinGen Ensembl |
|
|
CA1817283 rs755359262 |
452 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs932308838 CA53856366 |
453 | V>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1374324090 COSM3390838 CA348109235 |
453 | V>M | pancreas [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1436218065 CA348109226 |
454 | Y>S | No |
ClinGen gnomAD |
|
|
rs1157872116 CA348109216 |
455 | E>D | No |
ClinGen gnomAD |
|
| TCGA novel | 455 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs766724524 CA1817281 |
456 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
rs1418922434 CA348109210 |
456 | Y>S | No |
ClinGen gnomAD |
|
|
CA1817279 rs751018682 |
460 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3390837 rs762559384 CA1817277 |
461 | R>Q | Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs763640071 CA1817278 |
461 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs775069737 CA1817276 |
463 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs761386990 CA1817275 |
463 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 464 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348109168 rs1289911271 |
464 | E>K | No |
ClinGen gnomAD |
|
|
CA1817273 rs776520830 |
466 | C>W | No |
ClinGen ExAC gnomAD |
|
|
rs1573194804 CA348109145 |
467 | H>P | No |
ClinGen Ensembl |
|
|
rs1354682908 CA348109141 |
467 | H>Q | No |
ClinGen gnomAD |
|
|
CA53856364 rs199567558 |
469 | H>D | No |
ClinGen 1000Genomes |
|
|
CA1817272 rs141942088 |
470 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA348109118 rs1382127720 |
471 | L>M | No |
ClinGen gnomAD |
|
|
CA348109108 rs1287940346 |
472 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
rs375214904 CA1817270 |
474 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs375214904 CA53856363 |
474 | D>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs149599398 COSM1004955 CA1817268 |
475 | A>T | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1573194713 CA348109079 |
477 | C>R | No |
ClinGen Ensembl |
|
|
CA348109071 rs1189266638 |
478 | T>A | No |
ClinGen gnomAD |
|
|
CA348109072 rs1189266638 |
478 | T>P | No |
ClinGen gnomAD |
|
|
COSM1398629 CA348109058 rs1259672152 |
480 | G>R | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs1369823574 CA348109054 |
481 | A>T | No |
ClinGen TOPMed |
|
|
CA1817266 COSM3960928 rs755229256 |
481 | A>V | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
| TCGA novel | 484 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348109020 rs1269804780 |
486 | L>F | No |
ClinGen gnomAD |
|
|
rs1269804780 CA348109022 |
486 | L>I | No |
ClinGen gnomAD |
|
|
rs780492884 CA1817263 |
487 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs958478679 CA53856361 |
487 | Y>H | No |
ClinGen Ensembl |
|
|
rs780492884 CA348109014 |
487 | Y>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 488 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348108996 rs1246831675 |
489 | K>N | No |
ClinGen gnomAD |
|
| TCGA novel | 493 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA53856360 COSM3787836 rs1032769723 |
494 | R>C | pancreas [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs757962368 CA1817260 COSM200545 |
494 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs757962368 CA1817259 |
494 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752265203 CA1817258 |
496 | N>H | No |
ClinGen ExAC gnomAD |
|
|
CA1817257 rs764730765 |
497 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759254626 CA1817256 |
498 | G>C | No |
ClinGen ExAC gnomAD |
|
|
CA1817255 rs776266456 COSM1398628 |
499 | T>M | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 500 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817253 COSM1526975 rs760683299 COSM1266855 |
501 | G>R | lung oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1375857317 CA348108904 |
504 | H>L | No |
ClinGen gnomAD |
|
|
CA1817252 rs773338561 |
504 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs772145681 CA1817251 COSM1690860 |
505 | R>C | ovary Variant assessed as Somatic; 0.0 impact. skin [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs376753460 CA1817250 |
505 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs376753460 CA348108899 |
505 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1573194439 CA348108897 |
506 | K>Q | No |
ClinGen Ensembl |
|
| TCGA novel | 507 | G>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348108878 rs1211602212 |
508 | K>N | No |
ClinGen gnomAD |
|
|
CA1817248 rs768714929 |
508 | K>T | No |
ClinGen ExAC gnomAD |
|
|
rs1239396065 CA348108872 |
509 | V>A | No |
ClinGen TOPMed |
|
|
CA1817247 rs34558933 |
511 | L>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1817246 rs780368546 |
512 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746361790 CA1817244 |
513 | G>S | No |
ClinGen ExAC TOPMed |
|
|
CA1817240 rs200325346 |
516 | A>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs781622034 CA1817242 |
516 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA1817241 COSM267514 rs200325346 |
516 | A>V | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA1817237 rs754554820 |
518 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753592483 CA1817236 |
519 | C>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 520 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1817235 rs766262183 |
521 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1817234 rs150941884 |
522 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA348108791 rs1392084083 |
523 | S>N | No |
ClinGen gnomAD |
|
|
rs773142087 CA1817233 |
527 | P>S | No |
ClinGen ExAC gnomAD |
No associated diseases with Q96JF0
No regional properties for Q96JF0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q96JF0 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.3.1 | Sialyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi cisterna membrane | The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-galactoside alpha-2,6-sialyltransferase activity | Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| oligosaccharide metabolic process | The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. |
| protein glycosylation | A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. |
| sialylation | The covalent attachment of sialic acid to a substrate molecule. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q92184 | ST6GALNAC2 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | Gallus gallus (Chicken) | PR |
| Q92182 | ST6GAL1 | Beta-galactoside alpha-2,6-sialyltransferase 1 | Gallus gallus (Chicken) | PR |
| Q701R0 | ST6GAL2 | Beta-galactoside alpha-2,6-sialyltransferase 2 | Gallus gallus (Chicken) | PR |
| Q9UJ37 | ST6GALNAC2 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | Homo sapiens (Human) | PR |
| Q9BVH7 | ST6GALNAC5 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | Homo sapiens (Human) | PR |
| P15907 | ST6GAL1 | Beta-galactoside alpha-2,6-sialyltransferase 1 | Homo sapiens (Human) | PR |
| Q64685 | St6gal1 | Beta-galactoside alpha-2,6-sialyltransferase 1 | Mus musculus (Mouse) | PR |
| Q9QYJ1 | St6galnac5 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | Mus musculus (Mouse) | PR |
| P70277 | St6galnac2 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | Mus musculus (Mouse) | PR |
| P13721 | St6gal1 | Beta-galactoside alpha-2,6-sialyltransferase 1 | Rattus norvegicus (Rat) | PR |
| Q9SGD2 | GALT29A | Beta-1,6-galactosyltransferase GALT29A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKPHLKQWRQ | RMLFGIFAWG | LLFLLIFIYF | TDSNPAEPVP | SSLSFLETRR | LLPVQGKQRA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IMGAAHEPSP | PGGLDARQAL | PRAHPAGSFH | AGPGDLQKWA | QSQDGFEHKE | FFSSQVGRKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QSAFYPEDDD | YFFAAGQPGW | HSHTQGTLGF | PSPGEPGPRE | GAFPAAQVQR | RRVKKRHRRQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RRSHVLEEGD | DGDRLYSSMS | RAFLYRLWKG | NVSSKMLNPR | LQKAMKDYLT | ANKHGVRFRG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KREAGLSRAQ | LLCQLRSRAR | VRTLDGTEAP | FSALGWRRLV | PAVPLSQLHP | RGLRSCAVVM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SAGAILNSSL | GEEIDSHDAV | LRFNSAPTRG | YEKDVGNKTT | IRIINSQILT | NPSHHFIDSS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LYKDVILVAW | DPAPYSANLN | LWYKKPDYNL | FTPYIQHRQR | NPNQPFYILH | PKFIWQLWDI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IQENTKEKIQ | PNPPSSGFIG | ILIMMSMCRE | VHVYEYIPSV | RQTELCHYHE | LYYDAACTLG |
| 490 | 500 | 510 | 520 | ||
| AYHPLLYEKL | LVQRLNMGTQ | GDLHRKGKVV | LPGFQAVHCP | APSPVIPHS |