Q9LZM0

PR
Gene name
CYCD7-1 (At5g02110, T7H20.160)
Protein name
Putative cyclin-D7-1
Names
G1/S-specific cyclin-D7-1, CycD71
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G02110
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

286-341 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LZM0

Entry ID Method Resolution Chain Position Source
AF-Q9LZM0-F1 Predicted AlphaFoldDB

134 variants for Q9LZM0

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00601056 2 D>G No 1000Genomes
tmp_5_417136_C_A 17 P>Q No 1000Genomes
tmp_5_417148_C_A 21 P>Q No 1000Genomes
tmp_5_417161_C_A 25 H>Q No 1000Genomes
ENSVATH06907012 25 H>R No 1000Genomes
ENSVATH03006301 28 H>Y No 1000Genomes
ENSVATH06907014 36 Y>D No 1000Genomes
tmp_5_417195_C_T 37 P>S No 1000Genomes
ENSVATH06907015 40 D>N No 1000Genomes
ENSVATH06907016 41 A>S No 1000Genomes
ENSVATH10495118 43 T>K No 1000Genomes
tmp_5_417240_T_A 52 L>I No 1000Genomes
tmp_5_417255_T_G,C 57 C>G No 1000Genomes
tmp_5_417255_T_G,C 57 C>R No 1000Genomes
ENSVATH10495119 58 F>L No 1000Genomes
ENSVATH00601057 59 N>S No 1000Genomes
tmp_5_417306_T_A 74 L>I No 1000Genomes
tmp_5_417316_A_T 77 Y>F No 1000Genomes
ENSVATH10495121 80 H>Q No 1000Genomes
ENSVATH06907032 91 R>W No 1000Genomes
tmp_5_417646_C_T 103 A>V No 1000Genomes
ENSVATH10495124 110 V>I No 1000Genomes
tmp_5_417675_A_T 113 T>S No 1000Genomes
tmp_5_417789_A_T 120 N>Y No 1000Genomes
ENSVATH06907039 123 V>M No 1000Genomes
ENSVATH06907040 124 E>Q No 1000Genomes
tmp_5_417817_C_T 129 T>I No 1000Genomes
ENSVATH06907041 130 S>A No 1000Genomes
ENSVATH03006321 132 S>L No 1000Genomes
ENSVATH13877791 135 S>* No 1000Genomes
tmp_5_417841_T_G 137 F>C No 1000Genomes
tmp_5_417863_A_C 144 L>F No 1000Genomes
ENSVATH06907042 150 M>I No 1000Genomes
tmp_5_417885_G_A 152 G>S No 1000Genomes
ENSVATH06907043 153 L>V No 1000Genomes
ENSVATH10495158 159 V>G No 1000Genomes
ENSVATH06907044 160 N>K No 1000Genomes
tmp_5_417910_A_C 160 N>T No 1000Genomes
ENSVATH10495159 161 T>K No 1000Genomes
tmp_5_417915_G_A 162 V>I No 1000Genomes
ENSVATH13877792 163 A>S No 1000Genomes
tmp_5_417951_G_C 174 E>Q No 1000Genomes
ENSVATH06907045 180 V>G No 1000Genomes
ENSVATH03006322 181 T>A No 1000Genomes
ENSVATH03006324 184 T>N No 1000Genomes
tmp_5_417993_A_C 188 T>P No 1000Genomes
ENSVATH06907046 189 L>F No 1000Genomes
ENSVATH03006325 192 K>Q No 1000Genomes
ENSVATH10495162 193 I>T No 1000Genomes
tmp_5_418015_T_A 195 M>K No 1000Genomes
ENSVATH03006326 199 H>D No 1000Genomes
ENSVATH03006326 199 H>N No 1000Genomes
ENSVATH03006326 199 H>Y No 1000Genomes
ENSVATH00601061 201 I>T No 1000Genomes
ENSVATH13877793 203 N>K No 1000Genomes
ENSVATH13877794 204 R>G No 1000Genomes
tmp_5_418042_G_A 204 R>Q No 1000Genomes
tmp_5_418053_C_T 208 H>Y No 1000Genomes
tmp_5_418059_C_T 210 L>F No 1000Genomes
ENSVATH03006327 212 V>D No 1000Genomes
ENSVATH03006327 212 V>G No 1000Genomes
ENSVATH03006328 213 I>L No 1000Genomes
tmp_5_418069_T_C 213 I>T No 1000Genomes
tmp_5_418071_T_A 214 C>S No 1000Genomes
ENSVATH03006333 216 L>F No 1000Genomes
ENSVATH06907053 218 M>I No 1000Genomes
tmp_5_418185_C_T 220 Q>* No 1000Genomes
tmp_5_418199_C_A 224 S>R No 1000Genomes
tmp_5_418207_C_G 227 A>G No 1000Genomes
tmp_5_418221_T_A 232 W>R No 1000Genomes
ENSVATH10495235 234 L>F No 1000Genomes
ENSVATH06907057 235 M>L No 1000Genomes
ENSVATH03006334 237 D>E No 1000Genomes
ENSVATH06907058 237 D>N No 1000Genomes
ENSVATH00601069 240 C>R No 1000Genomes
ENSVATH10495236 242 E>V No 1000Genomes
tmp_5_418258_T_G 244 I>S No 1000Genomes
ENSVATH06907059 245 M>I No 1000Genomes
tmp_5_418266_C_T 247 L>F No 1000Genomes
tmp_5_418274_A_T 249 E>D No 1000Genomes
tmp_5_418279_A_T 251 N>I No 1000Genomes
ENSVATH10495237 251 N>Y No 1000Genomes
tmp_5_418281_C_T 252 H>Y No 1000Genomes
ENSVATH06907060 253 K>N No 1000Genomes
ENSVATH00601070 262 G>E No 1000Genomes
ENSVATH06907061 262 G>R No 1000Genomes
ENSVATH00601070 262 G>V No 1000Genomes
tmp_5_418315_T_A 263 M>K No 1000Genomes
ENSVATH06907062 266 R>Q No 1000Genomes
ENSVATH06907063 267 D>N No 1000Genomes
ENSVATH13877908 269 D>E No 1000Genomes
ENSVATH03006340 269 D>N No 1000Genomes
ENSVATH00601072 273 S>A No 1000Genomes
tmp_5_418348_G_A 274 R>K No 1000Genomes
ENSVATH10495238 275 R>K No 1000Genomes
ENSVATH10495239 276 R>I No 1000Genomes
ENSVATH10495239 276 R>K No 1000Genomes
tmp_5_418357_A_G 277 Y>C No 1000Genomes
ENSVATH03006341 277 Y>H No 1000Genomes
tmp_5_418361_T_A 278 S>R No 1000Genomes
ENSVATH00601073 281 R>K No 1000Genomes
ENSVATH03006342 281 R>S No 1000Genomes
ENSVATH00601074 282 S>N No 1000Genomes
tmp_5_418376_T_G 283 I>M No 1000Genomes
ENSVATH13877909 285 S>N No 1000Genomes
ENSVATH00601075
tmp_5_418382_T_G
 285 S>R No 1000Genomes
ENSVATH06907066 292 V>A No 1000Genomes
ENSVATH06907065 292 V>L No 1000Genomes
tmp_5_418416_G_A 297 G>R No 1000Genomes
tmp_5_418419_G_A 298 D>N No 1000Genomes
ENSVATH06907068 303 D>A No 1000Genomes
ENSVATH03006347 303 D>E No 1000Genomes
tmp_5_418434_G_A 303 D>N No 1000Genomes
ENSVATH03006351 318 R>K No 1000Genomes
ENSVATH03006351 318 R>M No 1000Genomes
ENSVATH06907071 321 G>E No 1000Genomes
ENSVATH06907070 321 G>R No 1000Genomes
ENSVATH03006352 322 N>I No 1000Genomes
ENSVATH06907073 324 Q>E No 1000Genomes
tmp_5_418502_C_G 325 D>E No 1000Genomes
tmp_5_418503_A_G 326 N>D No 1000Genomes
ENSVATH06907074 326 N>K No 1000Genomes
tmp_5_418507_T_G 327 I>S No 1000Genomes
ENSVATH06907075 332 R>K No 1000Genomes
ENSVATH03006354 333 M>K No 1000Genomes
ENSVATH03006354 333 M>T No 1000Genomes
tmp_5_418527_A_T 334 T>S No 1000Genomes
ENSVATH06907076 336 E>G No 1000Genomes
ENSVATH10495242 338 S>A No 1000Genomes
ENSVATH10495243 338 S>L No 1000Genomes
ENSVATH06907077 339 N>K No 1000Genomes
ENSVATH03006355 340 Y>H No 1000Genomes
ENSVATH03006355 340 Y>N No 1000Genomes
ENSVATH06907078 341 I>T No 1000Genomes

No associated diseases with Q9LZM0

1 regional properties for Q9LZM0

Type Name Position InterPro Accession
domain Thymidylate kinase-like domain 8 - 196 IPR039430

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cyclin-dependent protein kinase holoenzyme complex Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
cyclin-dependent protein serine/threonine kinase regulator activity Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

5 GO annotations of biological process

Name Definition
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
embryo development ending in seed dormancy The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
mitotic cell cycle phase transition The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
regulation of cyclin-dependent protein serine/threonine kinase activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.

13 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P30279 CCND2 G1/S-specific cyclin-D2 Homo sapiens (Human) PR
Q6ZMN8 CCNI2 Cyclin-I2 Homo sapiens (Human) PR
P30280 Ccnd2 G1/S-specific cyclin-D2 Mus musculus (Mouse) PR
Q8WNW2 CCND2 G1/S-specific cyclin-D2 Sus scrofa (Pig) PR
Q10QA2 CYCD5-3 Cyclin-D5-3 Oryza sativa subsp japonica (Rice) PR
Q0WQN9 CYCD4-2 Cyclin-D4-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SN11 CYCD3-3 Cyclin-D3-3 Arabidopsis thaliana (Mouse-ear cress) PR
O48790 CYCB1-4 Cyclin-B1-4 Arabidopsis thaliana (Mouse-ear cress) PR
A0MEB5 CYCA3-3 Cyclin-A3-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FMH5 CYCA3-1 Putative cyclin-A3-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8LGA1 CYCD4-1 Cyclin-D4-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C6A9 CYCA3-2 Cyclin-A3-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PFW3 SDS Cyclin-SDS Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDNLLCEESW PASPLTPEPL PNFRHRSHDN DVVKMYPEID AATMEEAIAM DLEKELCFNN
70 80 90 100 110 120
HGDKFVEFFV SKKLTDYRFH AFQWLIQTRS RLNLSYETVF SAANCFDRFV YMTCCDEWTN
130 140 150 160 170 180
WMVELVAVTS LSIASKFNEV TTPLLEELEM EGLTHMFHVN TVAQMELIIL KALEWRVNAV
190 200 210 220 230 240
TSYTFSQTLV SKIGMVGDHM IMNRITNHLL DVICDLKMLQ YPPSVVATAA IWILMEDKVC
250 260 270 280 290 300
RESIMNLFEQ NHKEKIVKCV DGMKNRDIDH QSSRRRYSEG RSILSLLQRG DVMNMNGDYN
310 320 330 340
VEDLSKIFQI FRYEKKKRDR GNHQDNIRPA KRMTIEMSNY I