Q9LVE2
PR
Gene name |
B'ZETA (At3g21650, MIL23.22) |
Protein name |
Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' zeta isoform |
Names |
AtB' zeta, PP2A, B' subunit, zeta isoform |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G21650 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LVE2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LVE2-F1 | Predicted | AlphaFoldDB |
39 variants for Q9LVE2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_7623339_C_T | 25 | G>E | No | 1000Genomes | |
| ENSVATH05879314 | 26 | G>V | No | 1000Genomes | |
| ENSVATH05879313 | 33 | A>T | No | 1000Genomes | |
| tmp_3_7623312_G_A | 34 | S>L | No | 1000Genomes | |
| ENSVATH05879312 | 39 | T>S | No | 1000Genomes | |
| tmp_3_7623267_G_A | 49 | S>L | No | 1000Genomes | |
| tmp_3_7623250_A_G | 55 | S>P | No | 1000Genomes | |
| ENSVATH10832268 | 57 | S>L | No | 1000Genomes | |
| ENSVATH00338544 | 64 | L>P | No | 1000Genomes | |
| ENSVATH00338543 | 70 | S>G | No | 1000Genomes | |
| tmp_3_7623085_G_C | 110 | P>A | No | 1000Genomes | |
| tmp_3_7623069_G_A | 115 | P>L | No | 1000Genomes | |
| ENSVATH00338542 | 120 | G>A | No | 1000Genomes | |
| ENSVATH02174238 | 185 | A>V | No | 1000Genomes | |
| tmp_3_7622848_T_C | 189 | S>G | No | 1000Genomes | |
| tmp_3_7622831_T_C | 194 | I>M | No | 1000Genomes | |
| tmp_3_7622823_A_C | 197 | M>R | No | 1000Genomes | |
| tmp_3_7622805_G_C | 203 | S>C | No | 1000Genomes | |
| ENSVATH00338541 | 204 | L>S | No | 1000Genomes | |
| tmp_3_7622793_G_T | 207 | A>D | No | 1000Genomes | |
| tmp_3_7622782_C_T | 211 | V>I | No | 1000Genomes | |
| ENSVATH10832234 | 246 | D>E | No | 1000Genomes | |
| ENSVATH10832233 | 275 | P>S | No | 1000Genomes | |
| ENSVATH05879295 | 293 | E>D | No | 1000Genomes | |
| ENSVATH05879294 | 295 | H>N | No | 1000Genomes | |
| tmp_3_7622443_G_A | 324 | L>F | No | 1000Genomes | |
| tmp_3_7622388_T_C | 342 | Q>R | No | 1000Genomes | |
| tmp_3_7622384_C_A | 343 | Q>H | No | 1000Genomes | |
| tmp_3_7622379_G_A | 345 | S>L | No | 1000Genomes | |
| ENSVATH05879286 | 393 | Q>* | No | 1000Genomes | |
| tmp_3_7621940_G_T | 461 | Q>K | No | 1000Genomes | |
| ENSVATH05879278 | 470 | V>L | No | 1000Genomes | |
| ENSVATH00338539 | 483 | D>N | No | 1000Genomes | |
| tmp_3_7621847_C_G | 492 | E>Q | No | 1000Genomes | |
| ENSVATH05879275 | 494 | V>E | No | 1000Genomes | |
| tmp_3_7621834_T_A | 496 | K>I | No | 1000Genomes | |
| ENSVATH05879274 | 520 | V>L | No | 1000Genomes | |
| ENSVATH10832230 | 524 | A>T | No | 1000Genomes | |
| ENSVATH00338538 | 525 | V>L | No | 1000Genomes |
No associated diseases with Q9LVE2
No regional properties for Q9LVE2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9LVE2 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| protein phosphatase type 2A complex | A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein phosphatase regulator activity | Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| brassinosteroid mediated signaling pathway | The series of molecular signals mediated by the detection of brassinosteroid. |
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
| negative regulation of brassinosteroid mediated signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway. |
| negative regulation of innate immune response | Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. |
| response to photooxidative stress | Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A4FV68 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | Bos taurus (Bovine) | PR |
| Q15172 | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | Homo sapiens (Human) | PR |
| Q15173 | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | Homo sapiens (Human) | PR |
| Q16537 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | Homo sapiens (Human) | PR |
| Q14738 | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | Homo sapiens (Human) | PR |
| Q61151 | Ppp2r5e | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | Mus musculus (Mouse) | PR |
| Q6PD03 | Ppp2r5a | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | Mus musculus (Mouse) | PR |
| O04375 | B'ALPHA | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' alpha isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LF36 | B'THETA | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RW96 | B'GAMMA | Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' gamma isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93YV6 | B'KAPPA | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQY6 | B'DELTA | Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B' delta isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LU89 | B'ETA | Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' eta isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIKQIFGKLP | RKPSKSLQND | SNGEGGVNNS | YYASNSSTTS | ISKPSSTSSK | SSSASGSRVA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NGTLAPNSMS | SNRNTNQGKK | PLGGDAVVQA | GPFPSSGGVY | EALPSFRDVP | ISEKPNLFIG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLSMCCVVFD | FSDPSKNLKE | KEIKRQTLLE | LVDYVASVGF | KFNDVSMQEL | TKMVAVNLFR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TFPSANHESK | ILEIHDMDDE | EPSLEPAWPH | VQVVYEILLR | FVASPMTDAK | LAKRYIDHSF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VLKLLDLFDS | EDQREREYLK | TILHRVYGKF | MVHRPYIRKA | INNIFYRFIS | ETEKHNGIAE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLEILGSIIN | GFALPLKEEH | KLFLLRALIP | LHKPKCSSVY | HQQLSYCIVQ | FVEKDFKLAD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TVIRGLLKYW | PVTNSSKEVM | FLGELEEVLE | ATQAAEFQRC | MVPLSRQIAR | CLNSSHFQVA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ERALFLWNND | HIRNLITQNH | KVIMPIVFPA | LERNTRGHWN | QAVQSLTINV | RKVLCEIDQV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LFDECLAKFQ | VEEVNKTEVK | AKRERTWQRL | EDLATSKTVV | TNEAVLVPRF | VSSVNLTTSS |
| SESTGS |