Q9LU89
PR
Gene name |
B'ETA (At3g26020, MPE11.19) |
Protein name |
Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' eta isoform |
Names |
AtB' eta, PP2A, B' subunit, eta isoform |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G26020 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LU89
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LU89-F1 | Predicted | AlphaFoldDB |
26 variants for Q9LU89
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH10997691 | 25 | G>S | No | 1000Genomes | |
| ENSVATH07978803 | 43 | T>S | No | 1000Genomes | |
| tmp_3_9514505_C_G,T | 48 | A>G | No | 1000Genomes | |
| tmp_3_9514505_C_G,T | 48 | A>V | No | 1000Genomes | |
| ENSVATH00351110 | 56 | S>P | No | 1000Genomes | |
| tmp_3_9514531_C_T | 57 | P>S | No | 1000Genomes | |
| ENSVATH00351111 | 58 | A>G | No | 1000Genomes | |
| ENSVATH05919586 | 59 | G>V | No | 1000Genomes | |
| tmp_3_9514561_G_A | 67 | G>S | No | 1000Genomes | |
| tmp_3_9514580_T_C | 73 | L>P | No | 1000Genomes | |
| ENSVATH00351114 | 75 | S>T | No | 1000Genomes | |
| tmp_3_9514596_C_A | 78 | N>K | No | 1000Genomes | |
| tmp_3_9514617_C_G | 85 | N>K | No | 1000Genomes | |
| tmp_3_9514631_C_T | 90 | P>L | No | 1000Genomes | |
| tmp_3_9514729_A_T | 123 | T>S | No | 1000Genomes | |
| tmp_3_9514738_A_G | 126 | T>A | No | 1000Genomes | |
| ENSVATH05919589 | 129 | I>M | No | 1000Genomes | |
| ENSVATH10997694 | 134 | I>V | No | 1000Genomes | |
| ENSVATH10997745 | 249 | C>S | No | 1000Genomes | |
| tmp_3_9515200_G_T | 280 | V>F | No | 1000Genomes | |
| tmp_3_9515264_A_G | 301 | N>S | No | 1000Genomes | |
| tmp_3_9515416_A_T | 352 | T>S | No | 1000Genomes | |
| tmp_3_9516358_C_T | 436 | P>S | No | 1000Genomes | |
| ENSVATH05919607 | 507 | R>Q | No | 1000Genomes | |
| ENSVATH05919608 | 508 | K>N | No | 1000Genomes | |
| tmp_3_9516578_C_T | 509 | A>V | No | 1000Genomes |
No associated diseases with Q9LU89
No regional properties for Q9LU89
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9LU89 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| protein phosphatase type 2A complex | A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein phosphatase regulator activity | Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| brassinosteroid mediated signaling pathway | The series of molecular signals mediated by the detection of brassinosteroid. |
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A4FV68 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | Bos taurus (Bovine) | PR |
| Q15173 | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | Homo sapiens (Human) | PR |
| Q16537 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | Homo sapiens (Human) | PR |
| Q14738 | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | Homo sapiens (Human) | PR |
| Q15172 | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | Homo sapiens (Human) | PR |
| Q61151 | Ppp2r5e | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | Mus musculus (Mouse) | PR |
| Q6PD03 | Ppp2r5a | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | Mus musculus (Mouse) | PR |
| O04375 | B'ALPHA | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' alpha isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RW96 | B'GAMMA | Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' gamma isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LVE2 | B'ZETA | Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' zeta isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93YV6 | B'KAPPA | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LF36 | B'THETA | Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQY6 | B'DELTA | Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B' delta isoform | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWKQILSKLP | NKKSSKHEHR | GREHGGHSSS | SSHTSGASTS | KSTDNGAAKS | HAKNASPAGK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SAASDSGFKD | GNLKSSGNNN | NNNNNGVFTP | YEALPSFKDV | PNTEKQNLFI | KKLNLCRVVF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DFTDPTKNIK | EKDIKRQTLL | ELVDYVNSPN | GKFSEVGIQE | VVRMVSANIF | RTLNPQPREN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KVIDALDLEE | EEPSMDLAWP | HLQLVYELFL | RFVASPETDT | KLAKRYIDQS | FVLRLLDLFD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SEDPRERDCL | KTILHRIYGK | FMVHRPFIRK | SINNIFYRFV | FETEKHNGIA | EFLEILGSII |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NGFALPLKDE | HKVFLVRVLI | PLHKPKCLQM | YHQQLSYCIT | QFVEKDCKLA | DTVIRGLLKY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WPVTNSSKEV | MFLNELEEVL | EATQPPEFQR | CMVPLFRQIA | RCLNSLHFQV | AERALFLWNN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NHIENLIMQN | RKVILPIIFP | ALERNAQKHW | NQAVHSLTLN | VRKIFHDLDP | ELFKECLAKF |
| 490 | 500 | ||||
| KEDESKAAET | EAKREATWKR | LEELGVRKAS |