Q9D572
Gene name |
Ubxn11 (D4Bwg1540e, Soc, Ubxd5) |
Protein name |
UBX domain-containing protein 11 |
Names |
Socius, UBX domain-containing protein 5 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:67586 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D572
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D572-F1 | Predicted | AlphaFoldDB |
31 variants for Q9D572
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388720120 | 14 | V>M | No | EVA | |
| rs3388714333 | 21 | V>A | No | EVA | |
| rs263619974 | 30 | V>I | No | EVA | |
| rs3388707188 | 56 | Y>* | No | EVA | |
| rs3388706125 | 81 | L>M | No | EVA | |
| rs32633611 | 100 | R>Q | No | EVA | |
| rs253072161 | 130 | Q>R | No | EVA | |
| rs220154375 | 132 | I>M | No | EVA | |
| rs27559979 | 146 | S>G | No | EVA | |
| rs232819468 | 159 | Q>E | No | EVA | |
| rs3388714642 | 188 | F>Y | No | EVA | |
| rs27544036 | 197 | K>R | No | EVA | |
| rs222194482 | 199 | M>L | No | EVA | |
| rs864279819 | 212 | E>G | No | EVA | |
| rs265300731 | 223 | R>Q | No | EVA | |
| rs3388724233 | 224 | F>L | No | EVA | |
| rs222693408 | 234 | V>L | No | EVA | |
| rs3388717101 | 248 | P>L | No | EVA | |
| rs3388714252 | 252 | P>L | No | EVA | |
| rs3413044095 | 256 | R>L | No | EVA | |
| rs3388726353 | 357 | N>K | No | EVA | |
| rs1133078330 | 376 | A>V | No | EVA | |
| rs220916899 | 382 | S>N | No | EVA | |
| rs3388717498 | 392 | L>Q | No | EVA | |
| rs3388726352 | 397 | R>H | No | EVA | |
| rs243935477 | 409 | L>V | No | EVA | |
| rs3388706082 | 426 | Q>* | No | EVA | |
| rs13468675 | 436 | E>G | No | EVA | |
| rs3388714667 | 467 | R>W | No | EVA | |
| rs246970567 | 477 | I>S | No | EVA | |
| rs214916081 | 484 | P>T | No | EVA |
No associated diseases with Q9D572
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ubiquitin binding | Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteasome-mediated ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3SZC4 | NSFL1C | NSFL1 cofactor p47 | Bos taurus (Bovine) | PR |
| Q5ZK10 | NSFL1C | NSFL1 cofactor p47 | Gallus gallus (Chicken) | PR |
| Q14CS0 | UBXN2B | UBX domain-containing protein 2B | Homo sapiens (Human) | PR |
| Q9UNZ2 | NSFL1C | NSFL1 cofactor p47 | Homo sapiens (Human) | PR |
| Q5T124 | UBXN11 | UBX domain-containing protein 11 | Homo sapiens (Human) | PR |
| Q99KJ0 | Ubxn2a | UBX domain-containing protein 2A | Mus musculus (Mouse) | PR |
| Q0KL01 | Ubxn2b | UBX domain-containing protein 2B | Mus musculus (Mouse) | PR |
| Q9CZ44 | Nsfl1c | NSFL1 cofactor p47 | Mus musculus (Mouse) | PR |
| O35987 | Nsfl1c | NSFL1 cofactor p47 | Rattus norvegicus (Rat) | PR |
| P0C627 | Ubxn2b | UBX domain-containing protein 2B | Rattus norvegicus (Rat) | PR |
| Q8R512 | Ubxn11 | UBX domain-containing protein 11 | Rattus norvegicus (Rat) | PR |
| F4IXN6 | PUX6 | Plant UBX domain-containing protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSPLASLSK | TRKVPLESES | VNPGRRGIRV | YGNEDEVDMW | NDGQDSEEKI | SLPSCYGGIG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| APVSRQGPHD | SELMASMTRK | LQELEQQLQA | QNDEMLSKER | KILDLEDLVQ | TLQQHQNNAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LQRQEELETQ | CIQLQRQIGE | MERFLSDYGL | QWVGEPMDQE | NSEEKTVSEN | DERDWMKAKK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FWKPGDSFVP | PEVDFDKLMA | SLQDLSELVE | GEAQVTPVPG | GARFRTLEPI | PLKVYRNGIM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MFDGPFRPFY | DPSTQRCLRD | ILDGFFPSEL | QRLYPDGVPF | KVSDLRNQIY | PEDGLGQFPG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EGRVVGRQKM | RKVTDRVEET | SGSRMTAEQF | LNRLPKCIIR | QGEVIDIRGP | IRDTLQNCCP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MPARIQEIIV | ETPALASERQ | RSQESPDMPM | PLLSMLRIKS | ENGEQAFLLM | MWPEDTIGDV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RKLLAQARDM | DSAAFEILST | FPPTVYQDDT | VTLQAAGLVP | NATLLLRTRR | ALLSNPISRP |
| GSLP |