Q8R512

PR
Gene name
Ubxn11 (Soc, Ubxd5)
Protein name
UBX domain-containing protein 11
Names
Socius, UBX domain-containing protein 5
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:192207
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-250 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8R512

Entry ID Method Resolution Chain Position Source
AF-Q8R512-F1 Predicted AlphaFoldDB

No variants for Q8R512

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8R512

No associated diseases with Q8R512

2 regional properties for Q8R512

Type Name Position InterPro Accession
domain UBX domain 386 - 464 IPR001012
domain SEP domain 224 - 300 IPR012989

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

1 GO annotations of molecular function

Name Definition
ubiquitin binding Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.

1 GO annotations of biological process

Name Definition
proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3SZC4 NSFL1C NSFL1 cofactor p47 Bos taurus (Bovine) PR
Q5ZK10 NSFL1C NSFL1 cofactor p47 Gallus gallus (Chicken) PR
Q14CS0 UBXN2B UBX domain-containing protein 2B Homo sapiens (Human) PR
Q9UNZ2 NSFL1C NSFL1 cofactor p47 Homo sapiens (Human) PR
Q5T124 UBXN11 UBX domain-containing protein 11 Homo sapiens (Human) PR
Q99KJ0 Ubxn2a UBX domain-containing protein 2A Mus musculus (Mouse) PR
Q0KL01 Ubxn2b UBX domain-containing protein 2B Mus musculus (Mouse) PR
Q9CZ44 Nsfl1c NSFL1 cofactor p47 Mus musculus (Mouse) PR
Q9D572 Ubxn11 UBX domain-containing protein 11 Mus musculus (Mouse) PR
O35987 Nsfl1c NSFL1 cofactor p47 Rattus norvegicus (Rat) PR
P0C627 Ubxn2b UBX domain-containing protein 2B Rattus norvegicus (Rat) PR
F4IXN6 PUX6 Plant UBX domain-containing protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSSPLASLSK TRKVPLESEP VNPGRRGIRI YGDEDEVDMV NDGQDSEEKI SLPSCYGGIG
70 80 90 100 110 120
RQGLMIHDSE LLTSMARKLQ ELEQQLKARN EEMLSKEQKI LALEDLVQTL QQHQSSTTRE
130 140 150 160 170 180
EELETQCIQL QRQVGEMERF LNDYGLQWVG EPMDQENSEG KIISESDERD WMKAKKFWKP
190 200 210 220 230 240
GDSIVPPEVD FDRLLSSLQD LSELVVEGEA QVTPVPGGAQ FRTLEPIPLK LYRNGIMMFD
250 260 270 280 290 300
GPFRPFYDPY TQRCLRDILD GFFPSELQRL YPDGVPFKVS DLRNQVYPED GLGPFPGEGR
310 320 330 340 350 360
VVGRQKIRKV TDRVEETSGS RMTAEKFLNR LPKCVIRQGE VIDIRGPIRD TLQNCCPMPV
370 380 390 400 410 420
RIQEIIVETP ALASERQRTQ ESPNMPVPPL SMLRIKSENG EQAFLLMMRP EDTIGDVRNL
430 440 450 460 470 480
LAQARDMDSA AFEILSTFPP TVYRDDTVTL QAAGLVPNAT LLLRTRRVLP ANPSFGTDSG
PGSLP