Q94A87
Gene name |
At1g10090 (T27I1.10) |
Protein name |
CSC1-like protein At1g10090 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G10090 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q94A87
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q94A87-F1 | Predicted | AlphaFoldDB |
44 variants for Q94A87
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00015093 | 16 | I>L | No | 1000Genomes | |
| tmp_1_3295114_C_T | 53 | R>H | No | 1000Genomes | |
| ENSVATH10882942 | 59 | A>T | No | 1000Genomes | |
| ENSVATH00015090 | 74 | E>D | No | 1000Genomes | |
| tmp_1_3294803_C_G | 101 | V>L | No | 1000Genomes | |
| ENSVATH04547856 | 109 | V>A | No | 1000Genomes | |
| ENSVATH00015086 | 119 | M>I | No | 1000Genomes | |
| tmp_1_3294488_A_G | 156 | S>P | No | 1000Genomes | |
| tmp_1_3294316_C_A | 172 | K>N | No | 1000Genomes | |
| ENSVATH04547852 | 194 | I>V | No | 1000Genomes | |
| tmp_1_3294188_G_A | 215 | A>V | No | 1000Genomes | |
| ENSVATH01030448 | 247 | V>I | No | 1000Genomes | |
| ENSVATH01030446 | 261 | V>A | No | 1000Genomes | |
| ENSVATH01030445 | 262 | L>I | No | 1000Genomes | |
| ENSVATH00015076 | 274 | I>L | No | 1000Genomes | |
| ENSVATH10882663 | 286 | L>P | No | 1000Genomes | |
| ENSVATH01030443 | 296 | E>K | No | 1000Genomes | |
| ENSVATH04547829 | 303 | V>L | No | 1000Genomes | |
| ENSVATH04547828 | 305 | F>L | No | 1000Genomes | |
| ENSVATH00015067 | 372 | T>A | No | 1000Genomes | |
| ENSVATH00015066 | 385 | K>R | No | 1000Genomes | |
| ENSVATH01030432 | 400 | E>V | No | 1000Genomes | |
| ENSVATH01030431 | 402 | V>I | No | 1000Genomes | |
| ENSVATH00015063 | 418 | T>A | No | 1000Genomes | |
| ENSVATH04547821 | 436 | S>N | No | 1000Genomes | |
| ENSVATH01030430 | 437 | Q>L | No | 1000Genomes | |
| tmp_1_3292163_A_G | 451 | I>T | No | 1000Genomes | |
| ENSVATH04547818 | 512 | V>I | No | 1000Genomes | |
| ENSVATH04547818 | 512 | V>L | No | 1000Genomes | |
| ENSVATH10882514 | 566 | L>Q | No | 1000Genomes | |
| tmp_1_3291686_T_C | 578 | K>R | No | 1000Genomes | |
| ENSVATH00015048 | 612 | V>I | No | 1000Genomes | |
| ENSVATH00015045 | 646 | Q>K | No | 1000Genomes | |
| ENSVATH10882335 | 693 | E>D | No | 1000Genomes | |
| tmp_1_3290780_G_T | 694 | S>Y | No | 1000Genomes | |
| ENSVATH04547806 | 700 | T>I | No | 1000Genomes | |
| tmp_1_3290731_A_C | 710 | D>E | No | 1000Genomes | |
| tmp_1_3290724_C_A | 713 | E>* | No | 1000Genomes | |
| ENSVATH00015041 | 733 | K>R | No | 1000Genomes | |
| ENSVATH13873157 | 746 | A>T | No | 1000Genomes | |
| ENSVATH04547803 | 749 | I>T | No | 1000Genomes | |
| ENSVATH04547802 | 750 | R>C | No | 1000Genomes | |
| ENSVATH04547801 | 751 | N>Y | No | 1000Genomes | |
| ENSVATH10882184 | 755 | F>I | No | 1000Genomes |
No associated diseases with Q94A87
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium activated cation channel activity | Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5T3F8 | TMEM63B | CSC1-like protein 2 | Homo sapiens (Human) | PR |
| Q9P1W3 | TMEM63C | Calcium permeable stress-gated cation channel 1 | Homo sapiens (Human) | PR |
| O94886 | TMEM63A | CSC1-like protein 1 | Homo sapiens (Human) | PR |
| Q91YT8 | Tmem63a | CSC1-like protein 1 | Mus musculus (Mouse) | PR |
| B5TYT3 | At1g11960 | CSC1-like protein At1g11960 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4HYR3 | At1g62320 | CSC1-like protein At1g62320 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5XEZ5 | CSC1 | Calcium permeable stress-gated cation channel 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9XEA1 | OSCA1 | Protein OSCA1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4IBD7 | RXW8 | CSC1-like protein RXW8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDVSALLTSA | GINIAICVVL | VSLYSILRKQ | PANYCVYFGR | LLSDGRVKRH | DPRWYERFAP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SPSWLVKAWE | TTEEEMLAAA | GLDAVVFIRM | VICSIRIFSI | VAVVCLAFVL | PVNYYGQKME |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HKEVHLESLG | VFTIENLNPR | SRWLWVHCLS | LYIISSAACA | LLYFEYKNIA | KKRLAHISGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ASKPSHFTVL | IRAIPQSPDQ | SYSETVSKYF | TNYYAPSYVS | HLMVYRDGFI | HRLMNETERM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CQAIKHVSPD | LSCNPSLKSC | VLCGPAATNS | FQIISNETDS | VKGLELGELT | LTTTEEERPV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AFVFFKSRYD | ALVVSEVLQT | PNPMLWVADL | APEPHDVHWR | NLRIPYRQLW | MRRIATLVGA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IAFMFVFLFP | VTFVQGLTQL | PTLSKNFPFL | KDLLNRRFME | QVITGYLPSV | ILVLFFYTVP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PLMMYFSTLE | GCVSRSQRKK | SACLKILYFT | IWNVFFVNIL | SGSVIRQFTV | LNSVRDVPAQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LAKLVPAQAG | FFMTYCFTSG | WAGLACEIMQ | PVGLIWNLIA | KVIVKNKEES | YETLRFPYHT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EIPRLLLFGL | LGFTNSVIAP | LILPFLLIYF | FFAYLIYKNQ | IINVYITKYE | SGGQYWPVFH |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NTTIFSLILS | QVIALGFFGL | KLSTVASGFT | IPLILLTLLF | SEYCRQRFAP | IFQKYPAEIL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IAMDRADEMT | GKMEEIHNNL | KVAYSQIPTC | SEESSKAGCT | SPCSDQELPD | SEELKPEKEN |
| 730 | 740 | 750 | 760 | ||
| LKADYIWEFQ | RSKSGLDLEV | KSCPSASPIR | NSPGFAEIYK | RT |