F4HYR3
Gene name |
At1g62320 (F24O1.4) |
Protein name |
CSC1-like protein At1g62320 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G62320 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4HYR3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4HYR3-F1 | Predicted | AlphaFoldDB |
56 variants for F4HYR3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_23044822_C_T | 12 | A>T | No | 1000Genomes | |
| ENSVATH05034335 | 37 | V>I | No | 1000Genomes | |
| ENSVATH05034333 | 67 | R>Q | No | 1000Genomes | |
| ENSVATH01436385 | 78 | D>A | No | 1000Genomes | |
| ENSVATH05034331 | 88 | I>T | No | 1000Genomes | |
| tmp_1_23044428_T_C | 112 | I>V | No | 1000Genomes | |
| ENSVATH13694623 | 135 | L>F | No | 1000Genomes | |
| tmp_1_23044320_T_C | 148 | I>V | No | 1000Genomes | |
| tmp_1_23044125_T_A | 182 | K>I | No | 1000Genomes | |
| ENSVATH13694618 | 182 | K>N | No | 1000Genomes | |
| tmp_1_23044112_C_T | 186 | M>I | No | 1000Genomes | |
| ENSVATH05034324 | 192 | Q>K | No | 1000Genomes | |
| tmp_1_23043961_C_T | 205 | V>I | No | 1000Genomes | |
| tmp_1_23043753_A_T | 247 | L>M | No | 1000Genomes | |
| ENSVATH01436372 | 251 | K>E | No | 1000Genomes | |
| ENSVATH14386836 | 278 | G>E | No | 1000Genomes | |
| ENSVATH14386835 | 286 | K>N | No | 1000Genomes | |
| ENSVATH14386814 | 290 | M>V | No | 1000Genomes | |
| ENSVATH14386813 | 295 | A>G | No | 1000Genomes | |
| ENSVATH14386813 | 295 | A>V | No | 1000Genomes | |
| ENSVATH14386811 | 305 | M>T | No | 1000Genomes | |
| ENSVATH13694601 | 306 | E>D | No | 1000Genomes | |
| tmp_1_23043417_C_A | 308 | R>S | No | 1000Genomes | |
| tmp_1_23043415_T_C | 309 | K>R | No | 1000Genomes | |
| tmp_1_23043383_G_A | 320 | Q>* | No | 1000Genomes | |
| ENSVATH00113335 | 320 | Q>P | No | 1000Genomes | |
| tmp_1_23043358_G_T | 328 | T>K | No | 1000Genomes | |
| tmp_1_23043251_C_T | 364 | A>T | No | 1000Genomes | |
| tmp_1_23043246_C_T | 365 | M>I | No | 1000Genomes | |
| ENSVATH05034303 | 398 | L>* | No | 1000Genomes | |
| tmp_1_23043128_C_G | 405 | E>Q | No | 1000Genomes | |
| ENSVATH05034297 | 420 | M>I | No | 1000Genomes | |
| ENSVATH00113329 | 442 | T>A | No | 1000Genomes | |
| tmp_1_23042934_T_C | 443 | I>V | No | 1000Genomes | |
| tmp_1_23042832_G_C | 477 | L>V | No | 1000Genomes | |
| tmp_1_23042823_C_T | 480 | V>I | No | 1000Genomes | |
| tmp_1_23042796_G_C | 489 | L>V | No | 1000Genomes | |
| tmp_1_23042789_G_T | 491 | S>Y | No | 1000Genomes | |
| ENSVATH13694588 | 503 | T>I | No | 1000Genomes | |
| ENSVATH01436360 | 552 | K>N | No | 1000Genomes | |
| ENSVATH00113327 | 562 | Q>H | No | 1000Genomes | |
| ENSVATH13694586 | 588 | V>A | No | 1000Genomes | |
| tmp_1_23042230_C_G | 628 | G>R | No | 1000Genomes | |
| ENSVATH00113325 | 630 | I>V | No | 1000Genomes | |
| tmp_1_23042149_G_C | 655 | P>A | No | 1000Genomes | |
| tmp_1_23042098_T_G | 672 | K>Q | No | 1000Genomes | |
| ENSVATH13694579 | 680 | V>I | No | 1000Genomes | |
| tmp_1_23041942_A_T | 688 | M>K | No | 1000Genomes | |
| tmp_1_23041750_G_C | 752 | A>G | No | 1000Genomes | |
| tmp_1_23041746_G_C | 753 | S>R | No | 1000Genomes | |
| ENSVATH13694571 | 759 | G>S | No | 1000Genomes | |
| tmp_1_23041691_C_T | 772 | G>S | No | 1000Genomes | |
| ENSVATH01436345 | 775 | K>N | No | 1000Genomes | |
| ENSVATH01436344 | 776 | P>A | No | 1000Genomes | |
| tmp_1_23041678_G_A | 776 | P>L | No | 1000Genomes | |
| ENSVATH01436344 | 776 | P>S | No | 1000Genomes |
No associated diseases with F4HYR3
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium activated cation channel activity | Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5T3F8 | TMEM63B | CSC1-like protein 2 | Homo sapiens (Human) | PR |
| Q9P1W3 | TMEM63C | Calcium permeable stress-gated cation channel 1 | Homo sapiens (Human) | PR |
| O94886 | TMEM63A | CSC1-like protein 1 | Homo sapiens (Human) | PR |
| Q91YT8 | Tmem63a | CSC1-like protein 1 | Mus musculus (Mouse) | PR |
| B5TYT3 | At1g11960 | CSC1-like protein At1g11960 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5XEZ5 | CSC1 | Calcium permeable stress-gated cation channel 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94A87 | At1g10090 | CSC1-like protein At1g10090 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9XEA1 | OSCA1 | Protein OSCA1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4IBD7 | RXW8 | CSC1-like protein RXW8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATLADIGLA | AAINILSALI | FLLLFAILRI | QPFNDRVYFP | KWYLKGVRSS | PVNSGAFVSK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IMNLDFRSYV | RFLNWMPDAL | KMPEPELIDH | AGLDSAVYLR | IYLIGLKIFG | PIALLSWSIL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VPVNWTSDGL | QLAKLRNVTS | SNIDKLSISN | VERGSDRFWA | HLVMAYAFTF | WTCYVLMKEY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EKIAAMRLSF | LQSEKRRADQ | FTVLVRNVPP | DSDESISENV | QHFFLVNHPD | HYLTHQVVYN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANELAKLVED | KKKMQNWLDY | YQLKYTRNKE | QRPRVKMGFL | GLWGKKVDAM | DHYTAEIEKL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SEQIMEERKR | IKKDDKSVMQ | AAFVSFKTRW | GAAVCAQTQQ | TKNPTEWLTE | WAPEAREMYW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PNLAMPYVSL | TVRRFVMHIA | FFFLTFFFII | PIAFVQSLAS | IEGIEKSAPF | LSPIVKNKLM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KSLIQGFLPG | IVLKLFLIFL | PTILMIMSKF | EGFISISSLE | RRAAFRYYIF | NLVNVFLGSV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ITGSAFEQLD | SFLKQSANDI | PRTVGVAIPI | KATFFITYIM | VDGWAGVAGE | IFRLKPLVIF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| HLKNFFFVKT | EKDREEAMDP | GQIDFYATEP | RIQLYFLLGL | VYAPVTPVLL | PFIIFFFGFA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| YLVFRHQIIN | VYNQKYESAG | AFWPDVHGRI | ISALIISQIL | LLGLMSTKGK | VQSTPFLLVL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| AILTFGFHRF | CKGRYESAFV | INPLQEAMIK | DTLERAREPN | LNLKGFLQNA | YVHPVFKDEE |
| 730 | 740 | 750 | 760 | 770 | |
| DSDEEGLIED | SDDEDCVVVQ | TKRQRSRRTT | VASSNASRGS | SQSTPFNQLD | LGKGKPET |