Q94165
Gene name |
ceh-34 (C10G8.6) |
Protein name |
Homeobox protein ceh-34 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_C10G8.6 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q94165
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q94165-F1 | Predicted | AlphaFoldDB |
No variants for Q94165
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q94165 | |||||
No associated diseases with Q94165
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| transcription regulator complex | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| mesodermal cell fate specification | The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
| positive regulation of apoptotic process involved in development | Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O93307 | SIX6 | Homeobox protein SIX6 | Gallus gallus (Chicken) | PR |
| Q95RW8 | Optix | Protein Optix | Drosophila melanogaster (Fruit fly) | PR |
| O95343 | SIX3 | Homeobox protein SIX3 | Homo sapiens (Human) | PR |
| O95475 | SIX6 | Homeobox protein SIX6 | Homo sapiens (Human) | PR |
| Q15475 | SIX1 | Homeobox protein SIX1 | Homo sapiens (Human) | PR |
| Q9NPC8 | SIX2 | Homeobox protein SIX2 | Homo sapiens (Human) | PR |
| Q9QZ28 | Six6 | Homeobox protein SIX6 | Mus musculus (Mouse) | PR |
| Q62233 | Six3 | Homeobox protein SIX3 | Mus musculus (Mouse) | PR |
| Q62231 | Six1 | Homeobox protein SIX1 | Mus musculus (Mouse) | PR |
| Q62232 | Six2 | Homeobox protein SIX2 | Mus musculus (Mouse) | PR |
| Q6DHF9 | six1a | Homeobox protein six1a | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q6NZ04 | six1b | Homeobox protein six1b | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQQSYNPQNS | LTATTSYSEQ | EIVCICESLF | NEGLQTGRTE | QLANFIYNLP | QCYQVMESVL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KAQALVYFTT | QNWKMLYKLL | ECSKFSPHNH | TVLQNLWLDA | HYKEAAKTKD | RELGAVCKYR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRKKNPFPNT | IWDGEETNYC | FKSKSRNVLR | DAYKKCQYPS | VEDKRRLAQQ | TELSIIQVSN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WFKNKRQRER | AAGQLDRSSA | RSNDSDDGSS | GCESKPPMNI | DSPAPPPLPT | SFDLQPYYPS |
| 250 | |||||
| PYTFAPHCDF | SYIQNL |