Q8H1R4

PR
Gene name
ABCI10 (EMB2751, NAP13, At4g33460, F17M5.220)
Protein name
ABC transporter I family member 10
Names
ABC transporter ABCI.10, AtABCI10, Non-intrinsic ABC protein 13, Protein EMBRYO DEFECTIVE 2751
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G33460
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8H1R4

Entry ID Method Resolution Chain Position Source
AF-Q8H1R4-F1 Predicted AlphaFoldDB

14 variants for Q8H1R4

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_16100091_G_A 8 A>V No 1000Genomes
tmp_4_16100056_T_C 20 I>V No 1000Genomes
ENSVATH00550510 23 S>R No 1000Genomes
ENSVATH06818214 50 S>N No 1000Genomes
ENSVATH14331621 67 I>V No 1000Genomes
tmp_4_16099522_G_A 96 P>L No 1000Genomes
ENSVATH14331619 98 S>T No 1000Genomes
tmp_4_16099004_G_A 156 R>C No 1000Genomes
ENSVATH00550504 157 D>N No 1000Genomes
tmp_4_16098897_T_C 163 I>V No 1000Genomes
tmp_4_16098833_C_G 184 C>S No 1000Genomes
ENSVATH14331617 189 L>S No 1000Genomes
tmp_4_16098384_T_C 253 T>A No 1000Genomes
ENSVATH06818204 263 S>L No 1000Genomes

No associated diseases with Q8H1R4

4 regional properties for Q8H1R4

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 40 - 267 IPR003439
domain AAA+ ATPase domain 69 - 244 IPR003593
domain ABC transporter, CbiO/EcfA subunit 41 - 244 IPR015856
conserved_site ABC transporter-like, conserved site 166 - 180 IPR017871

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
chloroplast inner membrane The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.

1 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

3 GO annotations of biological process

Name Definition
chloroplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
transition metal ion homeostasis Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q12298 YDR061W Uncharacterized ABC transporter ATP-binding protein YDR061W Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
O95342 ABCB11 Bile salt export pump Homo sapiens (Human) PR
P08183 ABCB1 ATP-dependent translocase ABCB1 Homo sapiens (Human) PR
P21440 Abcb4 Phosphatidylcholine translocator ABCB4 Mus musculus (Mouse) PR
P06795 Abcb1b ATP-dependent translocase ABCB1 Mus musculus (Mouse) PR
P21447 Abcb1a ATP-dependent translocase ABCB1 Mus musculus (Mouse) PR
Q9QY30 Abcb11 Bile salt export pump Mus musculus (Mouse) PR
O70127 Abcb11 Bile salt export pump Rattus norvegicus (Rat) PR
Q9ZR72 ABCB1 ABC transporter B family member 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LJX0 ABCB19 ABC transporter B family member 19 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MNGHCLFAAS PPRLFPLRSI SSSVSPSGSY RIKFSDNVAV ECRNLCFSVS TRQGISVPIL
70 80 90 100 110 120
RDCSFRIPSG QLWMILGPNG CGKSTLLKIL AGVVNPSSGT VFVEKPKNFV FQNPDHQVVM
130 140 150 160 170 180
PTVEADVAFG LGKYHDMNQE EVKSRVIKAL EAVGMRDYMQ RPIQTLSGGQ KQRIAIAGAL
190 200 210 220 230 240
AEACKVLLLD ELTTFLDESD QMGVIKAVKD LINAKKGDVT ALWVTHRLEE LKYADGAVYM
250 260 270
ENGRVVRHGD AATISDFIKA KQSSYIDQIG S