Q12298
Gene name |
YDR061W (D4241) |
Protein name |
Uncharacterized ABC transporter ATP-binding protein YDR061W |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YDR061W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q12298
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q12298-F1 | Predicted | AlphaFoldDB |
18 variants for Q12298
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s04-574230 | 24 | P>S | No | SGRP | |
| s04-574320 | 54 | D>N | No | SGRP | |
| s04-574500 | 114 | Q>* | No | SGRP | |
| s04-574636 | 159 | V>A | No | SGRP | |
| s04-574750 | 197 | I>T | No | SGRP | |
| s04-574798 | 213 | S>N | No | SGRP | |
| s04-574801 | 214 | G>A | No | SGRP | |
| s04-574931 | 257 | M>I | No | SGRP | |
| s04-574950 | 264 | A>T | No | SGRP | |
| s04-574965 | 269 | E>Q | No | SGRP | |
| s04-574986 | 276 | N>D | No | SGRP | |
| s04-575465 | 435 | E>D | No | SGRP | |
| s04-575484 | 442 | K>E | No | SGRP | |
| s04-575494 | 445 | G>D | No | SGRP | |
| s04-575515 | 452 | S>I | No | SGRP | |
| s04-575531 | 457 | Q>H | No | SGRP | |
| s04-575734 | 525 | R>K | No | SGRP | |
| s04-575771 | 537 | M>I | No | SGRP |
No associated diseases with Q12298
3 regional properties for Q12298
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 8 - 265 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 307 - 537 | IPR003439-2 |
| domain | AAA+ ATPase domain | 331 - 538 | IPR003593 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8H1R4 | ABCI10 | ABC transporter I family member 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTNKFVVRI | TNALFKSSLA | SNSPPVYPKR | IRHFEILPNE | KWVIWGPGKG | KFLDVLNNKY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ICEPPLSLRF | GFLKESSNIL | PRIEQVAFKG | VMPTAHLSAR | YEYFKDDYDQ | TCKQFIFDKA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGSNAVSYKV | ETNNRQINME | LYNALVENLN | LSSLQDRWVM | GLSNGQMRRA | RLARSILKEP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DLLLIDDPFL | GLDPAAIATI | SQFLAKYDSI | EVSGGCPIVI | GLRYQDTIPA | WCTHICCVDE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KNGILFEGPI | EKLQSKMDET | RSRALKELEQ | LKKASNSKED | ISINDLICIH | PMYGKKEHEI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IKMPHLIELD | GLSVSYKGEA | VLENLHWKVQ | PGSKWHIRGD | NGSGKSTLLS | LLTAEHPQSW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NSRVIDNGVP | RRTGKTNYFD | LNSKIGMSSP | ELHAIFLKNA | GGRLNIRESV | ATGYHEASSN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NYLPIWKRLD | KNSQEIVNMY | LKYFGLDKDA | DSVLFEQLSV | SDQKLVLFVR | SLIKMPQILI |
| 490 | 500 | 510 | 520 | 530 | |
| LDEAFSGMEV | EPMMRCHEFL | EEWPGTVLVV | AHVAEETPKC | AHYLRLISPG | EYEIGDMEN |