Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q75KU4

Entry ID Method Resolution Chain Position Source
AF-Q75KU4-F1 Predicted AlphaFoldDB

No variants for Q75KU4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q75KU4

No associated diseases with Q75KU4

3 regional properties for Q75KU4

Type Name Position InterPro Accession
domain EF-hand domain 67 - 102 IPR002048-1
domain EF-hand domain 104 - 183 IPR002048-2
binding_site EF-Hand 1, calcium-binding site 161 - 173 IPR018247

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor
  • Aleurone cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).
kinase binding Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.

1 GO annotations of biological process

Name Definition
calcium-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.

13 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P63099 PPP3R1 Calcineurin subunit B type 1 Bos taurus (Bovine) PR
A0AVX7 TESC Calcineurin B homologous protein 3 Gallus gallus (Chicken) PR
P63098 PPP3R1 Calcineurin subunit B type 1 Homo sapiens (Human) PR
Q96BS2 TESC Calcineurin B homologous protein 3 Homo sapiens (Human) PR
Q96LZ3 PPP3R2 Calcineurin subunit B type 2 Homo sapiens (Human) PR
Q9NS61 KCNIP2 Kv channel-interacting protein 2 Homo sapiens (Human) PR
Q9JKL5 Tesc Calcineurin B homologous protein 3 Mus musculus (Mouse) PR
Q63810 Ppp3r1 Calcineurin subunit B type 1 Mus musculus (Mouse) PR
Q9JJ69 Kcnip2 Kv channel-interacting protein 2 Mus musculus (Mouse) PR
Q9QXT8 Kcnip3 Calsenilin Mus musculus (Mouse) PR
P28470 Ppp3r2 Calcineurin subunit B type 2 Rattus norvegicus (Rat) PR
P63100 Ppp3r1 Calcineurin subunit B type 1 Rattus norvegicus (Rat) PR
Q7XC27 CBL1 Calcineurin B-like protein 1 Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MGCASSKQFK RPPGYEEPAV LAAQTTFTVN EVEALRELYN KMSYSIIKDG LIHKEEFQLA
70 80 90 100 110 120
LFRNSRKANL FADRVFDLFD LKRNGVIEFG EFVRSLSVFH PKAPKSEKTA FAFKLYDLRG
130 140 150 160 170 180
TGYIEKEELR EMVLALLDES DLHLSECAVE AIVDNTFSQA DSNGDGRIDP EEWEEFVKAN
190 200
PASLRNMSLP YLQDITMAFP SFVMHSEAHD