Q64093
PR
Gene name |
Slc6a20 |
Protein name |
Sodium- and chloride-dependent transporter XTRP3 |
Names |
Sodium/imino-acid transporter 1, Solute carrier family 6 member 20, Transporter rB21A |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:113918 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q64093
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q64093-F1 | Predicted | AlphaFoldDB |
No variants for Q64093
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q64093 | |||||
No associated diseases with Q64093
No regional properties for Q64093
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q64093 | |||
Functions
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| apical plasma membrane | The region of the plasma membrane located at the apical end of the cell. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| amino acid transmembrane transporter activity | Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. |
| amino-acid betaine transmembrane transporter activity | Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid. |
| L-proline transmembrane transporter activity | Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid. |
| neutral amino acid transmembrane transporter activity | Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. |
| proline:sodium symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in). |
| solute:sodium symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in). |
15 GO annotations of biological process
| Name | Definition |
|---|---|
| amino acid import across plasma membrane | The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. |
| amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| amino-acid betaine transport | The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| anion transmembrane transport | The process in which an anion is transported across a membrane. |
| cation transmembrane transport | The process in which a cation is transported across a membrane. |
| glycine import across plasma membrane | The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol. |
| glycine transport | The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| L-alpha-amino acid transmembrane transport | The directed movement of L-alpha-amino acid across a membrane. |
| L-amino acid transport | The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| L-proline import across plasma membrane | The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol. |
| neutral amino acid transport | The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| proline import across plasma membrane | The directed movement of proline from outside of a cell into the cytoplasmic compartment. |
| proline transmembrane transport | The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore. |
| proline transport | The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| sodium ion transmembrane transport | A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P51143 | SLC6A2 | Sodium-dependent noradrenaline transporter | Bos taurus (Bovine) | PR |
| Q9XS59 | SLC6A15 | Sodium-dependent neutral amino acid transporter B(0)AT2 | Bos taurus (Bovine) | PR |
| P23975 | SLC6A2 | Sodium-dependent noradrenaline transporter | Homo sapiens (Human) | PR |
| Q9H2J7 | SLC6A15 | Sodium-dependent neutral amino acid transporter B(0)AT2 | Homo sapiens (Human) | PR |
| Q9H1V8 | SLC6A17 | Sodium-dependent neutral amino acid transporter SLC6A17 | Homo sapiens (Human) | PR |
| Q9GZN6 | SLC6A16 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 | Homo sapiens (Human) | PR |
| Q9D687 | Slc6a19 | Sodium-dependent neutral amino acid transporter B(0)AT1 | Mus musculus (Mouse) | PR |
| O88576 | Slc6a18 | Sodium-dependent neutral amino acid transporter B(0)AT3 | Mus musculus (Mouse) | PR |
| Q8BJI1 | Slc6a17 | Sodium-dependent neutral amino acid transporter SLC6A17 | Mus musculus (Mouse) | PR |
| O55192 | Slc6a2 | Sodium-dependent noradrenaline transporter | Mus musculus (Mouse) | PR |
| O88575 | Slc6a20b | Sodium- and chloride-dependent transporter XTRP3B | Mus musculus (Mouse) | PR |
| P23978 | Slc6a1 | Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Rat) | PR |
| P28570 | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Rat) | PR |
| P31647 | Slc6a11 | Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Rat) | PR |
| P31662 | Slc6a17 | Sodium-dependent neutral amino acid transporter SLC6A17 | Rattus norvegicus (Rat) | PR |
| Q62687 | Slc6a18 | Sodium-dependent neutral amino acid transporter B(0)AT3 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRLAIKRRAS | RGQRPGPDEK | RARDMEKARP | QWGNPLQFVF | ACISYAVGLG | NVWRFPYLCQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MYGGGSFLVP | YLIMLIVEGM | PLLYLELAVG | QRMRQGSIGA | WRTISPYLSG | VGVASVVVSF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLSMYYNVIN | AWGFWYLFHS | FQDPLPWSVC | PLNSNRTGYD | EECEKASSTQ | YFWYRKTLNI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPSIQENGGV | QWEPALCLTL | AWLMVYLCIL | RGTESTGKVV | YFTALMPYCV | LIIYLVRGLT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LHGATNGLMY | MFTPKIEQLA | NPKAWINAAT | QIFFSLGLGF | GSLIAFASYN | EPSNDCQKHA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VIVSVINSST | SIFASIVTFS | IYGFKATFNY | ENCLNKVILL | LTNSFDLEDG | FLTASNLEEV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KDYLASTYPN | KYSEVFPHIR | NCSLESELNT | AVQGTGLAFI | VYAEAIKNME | VSQLWSVLYF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FMLLMLGMGS | MLGNTAAILT | PLTDSKVISS | YLPKEAISGL | VCLINCAVGM | VFTMEAGNYW |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FDIFNDYAAT | LSLLLIVLVE | TIAVCYVYGL | RRFESDLRAM | TGRPLNWYWK | AMWAFVSPLL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IIGLFIFYLS | DYILTGTLQY | QAWDATQGQL | VTKDYPPHAL | AVIGLLVASS | TMCIPLVALG |
| 610 | |||||
| TFIRNRLKRG | GSSPVA |