Q53GG5
PR
Gene name |
PDLIM3 (ALP) |
Protein name |
PDZ and LIM domain protein 3 |
Names |
Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:27295 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q53GG5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q53GG5-F1 | Predicted | AlphaFoldDB |
345 variants for Q53GG5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
RCV000822478 rs1227606973 CA358932890 |
3 | Q>R | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP |
|
RCV000183698 RCV002345644 CA335491 RCV000766562 RCV001364044 rs781358846 |
4 | T>M | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV001070340 rs2095752062 |
9 | G>S | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV000852989 RCV001721144 rs146768859 RCV000456516 CA335479 |
10 | P>L | Hypertrophic cardiomyopathy Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
CA112059605 RCV001037511 rs150125560 |
14 | G>S | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ESP TOPMed dbSNP gnomAD |
|
rs758987751 RCV001065995 CA3159926 |
16 | R>M | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
rs2095751946 RCV001226455 |
19 | G>A | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV001227246 rs1305441463 |
20 | G>C | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV001060524 rs2095730997 |
36 | S>N | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
rs2095730947 RCV001308782 |
44 | C>Y | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
rs778943215 CA3159897 RCV000535572 |
47 | D>E | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
rs754889669 CA3159893 RCV000795072 |
54 | G>S | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV001701792 RCV002518186 RCV000213791 RCV000462391 CA3159890 rs142951316 |
57 | T>A | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
RCV001313161 rs199476399 RCV000024530 |
60 | M>missing | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV001325423 rs770996211 |
88 | W>C | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV001208426 CA3159854 rs373657946 |
93 | S>C | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
RCV001296493 rs2095726024 |
106 | E>missing | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
CA215392 RCV000629177 rs199476400 RCV000024533 |
106 | E>A | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
rs777447396 RCV001242659 CA3159811 |
112 | G>R | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
RCV001349047 rs769389710 CA3159810 |
116 | E>Q | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
rs1295481759 RCV001302130 CA358924990 |
118 | K>N | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
RCV000852988 rs751951109 RCV002453933 CA3159805 |
122 | R>Q | Restrictive cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
RCV000024531 CA215388 RCV000181008 RCV000621333 VAR_050166 rs11944325 RCV001082000 |
127 | V>M | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
rs2095711219 RCV001043875 |
130 | G>S | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
rs773342819 CA3159776 RCV001316293 |
141 | I>T | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA3159775 RCV002332604 rs769851440 RCV000797377 |
147 | R>C | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA3159774 rs528843301 RCV000560811 RCV002521532 RCV000424303 |
147 | R>H | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
rs730880177 RCV000157406 CA346581 |
159 | I>N | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000233406 rs878854982 CA10582224 |
171 | A>T | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar dbSNP gnomAD |
|
CA3159762 RCV002348272 RCV000467359 rs138115202 |
177 | E>A | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
CA3159761 RCV000534728 rs566270712 |
178 | M>T | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD |
|
CA112044712 CA3159759 RCV000548484 rs765318874 RCV001046967 |
183 | V>L | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV001048479 rs2095701355 |
185 | I>T | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinVar dbSNP |
|
CA16618039 RCV002526986 rs1064796959 RCV000486015 |
199 | D>E | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
RCV002360779 CA358923490 RCV000697320 rs1561192175 |
219 | L>F | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV001201563 rs768821275 CA3159728 |
222 | E>K | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
rs747243505 RCV001243364 RCV002366072 CA3159727 |
226 | S>L | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000629182 rs201185673 RCV001756013 RCV000619173 CA3159726 |
228 | P>L | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
RCV002375246 RCV001234833 rs148256486 CA112043810 |
232 | D>E | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
RCV000852987 RCV001702442 RCV000476923 rs143121072 CA3159720 |
233 | V>L | Cardiomyopathy Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
RCV001246970 rs143121072 COSM3392809 CA3159721 |
233 | V>M | pancreas Primary dilated cardiomyopathy [Cosmic, ClinVar] | Yes |
ClinGen cosmic curated ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
rs765915778 CA3159718 RCV001230247 |
235 | R>Q | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000786183 RCV001082207 rs142143310 RCV000509295 CA335485 RCV000221631 |
239 | D>N | Primary dilated cardiomyopathy Familial cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
rs780392840 CA3159711 RCV001216557 |
242 | N>S | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
CA358922759 RCV000801158 rs1306620317 |
243 | E>K | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
RCV000232736 RCV000181009 RCV000620242 CA215390 rs62347360 RCV000024532 |
245 | T>I | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
RCV000208383 CA088495 rs377158204 RCV002515550 |
248 | R>H | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
rs781084216 CA3159707 RCV003169014 RCV000820830 |
250 | S>L | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
rs730880178 RCV000157407 CA346583 |
258 | G>E | Primary familial hypertrophic cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar dbSNP gnomAD |
|
rs1554037747 RCV002413792 CA358922450 RCV000629181 |
260 | V>G | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
rs878854983 RCV002411057 CA10582223 RCV000227639 |
260 | V>M | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP |
|
rs750061720 RCV000695472 CA3159685 |
265 | D>G | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
rs373419233 RCV002419001 CA3159684 RCV001340359 |
267 | R>C | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
rs1188446991 RCV001702091 RCV001234012 CA358921436 |
268 | P>L | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
CA112042635 rs542630585 RCV001231601 |
268 | P>T | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
CA3159680 RCV000786185 RCV001869178 rs764497554 |
271 | T>M | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000629180 CA358921283 rs150070443 |
279 | T>K | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
RCV000234315 COSM3392807 rs150070443 CA3159672 |
279 | T>M | pancreas Primary dilated cardiomyopathy [Cosmic, ClinVar] | Yes |
ClinGen cosmic curated ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
rs779988849 RCV000629179 CA3159669 |
283 | G>S | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA3159656 rs768354891 RCV000816311 |
297 | C>Y | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
RCV000619134 RCV000786184 rs143812960 CA335475 RCV000629178 |
299 | S>N | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
CA358919911 RCV001857949 RCV000522798 rs1326853948 |
305 | V>M | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar dbSNP gnomAD |
|
rs1561187562 RCV001326029 CA358919899 |
306 | V>M | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV000629183 rs200273032 CA335487 RCV000183696 RCV002516933 |
309 | R>Q | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
RCV002377441 rs146092339 RCV001339712 CA3159633 |
310 | D>N | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
RCV000699853 CA3159630 RCV002533575 rs755255012 |
313 | R>Q | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA3159623 RCV000793921 rs756047162 RCV002370074 |
319 | V>M | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000459101 CA16611619 RCV002379419 rs1060500600 |
331 | G>V | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar dbSNP gnomAD |
|
RCV000519664 RCV001223260 CA3159612 rs747338250 |
336 | E>G | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA3159607 rs368815493 RCV000796336 |
342 | E>K | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
CA247709 rs569673500 RCV001485614 RCV000180318 |
343 | T>A | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD |
|
RCV000702610 RCV002388320 CA3159603 rs373408599 |
345 | A>T | Primary dilated cardiomyopathy Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
CA358919256 RCV000521953 RCV002527631 rs1179953014 |
347 | A>V | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP |
|
CA3159599 rs764823333 RCV001065414 |
348 | R>H | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000557125 rs1554037057 CA358919194 |
358 | V>I | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
CA335489 RCV001062027 rs779267023 RCV000183697 |
361 | Y>C | Primary dilated cardiomyopathy [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA358932904 rs1306716699 |
2 | P>L | No |
ClinGen gnomAD |
|
|
rs1224883567 CA358932917 |
2 | P>S | No |
ClinGen gnomAD |
|
|
CA358932898 rs1301471750 |
3 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1000933182 CA112059646 |
4 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
CA358932876 rs781358846 |
4 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159934 rs751837590 |
5 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159933 rs371901477 |
6 | I>F | No |
ClinGen ESP ExAC gnomAD |
|
|
rs372538185 CA112059626 |
6 | I>N | No |
ClinGen ESP TOPMed |
|
|
rs997411356 CA112059624 |
7 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA358932818 rs1360143548 |
7 | L>P | No |
ClinGen gnomAD |
|
|
CA358932802 rs1178742958 |
8 | P>A | No |
ClinGen gnomAD |
|
|
CA3159931 rs572128606 |
8 | P>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs572128606 CA112059622 |
8 | P>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3159930 rs572128606 |
8 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA358932786 rs1179332943 |
9 | G>D | No |
ClinGen gnomAD |
|
|
CA358932719 rs1194638169 |
12 | P>L | No |
ClinGen gnomAD |
|
|
rs775251189 CA3159929 |
12 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs767058196 CA3159928 |
13 | W>G | No |
ClinGen ExAC gnomAD |
|
|
CA358932632 rs1345291628 |
16 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1378501267 CA358932593 |
19 | G>R | No |
ClinGen gnomAD |
|
|
rs774385688 CA3159924 |
20 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA358932576 rs1305441463 |
20 | G>S | No |
ClinGen gnomAD |
|
|
CA3159923 rs773605275 |
21 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA358932527 rs1464915127 |
22 | D>G | No |
ClinGen gnomAD |
|
|
CA3159921 rs748724098 |
23 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs781486882 CA3159920 |
25 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs971677958 CA112059558 |
26 | P>R | No |
ClinGen Ensembl |
|
|
CA3159918 rs747078028 |
29 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs780461100 CA3159917 |
30 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs758667413 CA3159916 |
31 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs182803361 CA3159902 |
38 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1232029998 CA358929699 |
43 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs758509064 CA3159899 |
45 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1402305678 CA358929606 |
46 | G>R | No |
ClinGen gnomAD |
|
|
CA3159898 rs746105849 |
47 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1387380333 CA358929536 |
48 | V>I | No |
ClinGen gnomAD |
|
|
rs1436263682 CA358929476 |
49 | I>V | No |
ClinGen gnomAD |
|
|
rs1393009610 CA358929387 |
51 | A>S | No |
ClinGen gnomAD |
|
|
CA3159896 rs755994888 |
51 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752432016 CA3159895 |
52 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358929171 rs1415876308 |
56 | G>E | No |
ClinGen TOPMed |
|
|
RCV000480269 rs754882710 |
58 | E>missing | No |
ClinVar dbSNP |
|
|
rs1561201996 CA358929124 |
58 | E>G | No |
ClinGen Ensembl |
|
|
CA3159888 rs764788096 |
60 | M>L | No |
ClinGen ExAC gnomAD |
|
|
CA3159887 rs762274624 |
62 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
CA358928923 rs1259274846 |
63 | A>V | No |
ClinGen gnomAD |
|
|
rs776834572 CA3159886 |
64 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA112053623 rs1030481395 |
64 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA3159885 rs769091239 |
65 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159883 rs776072095 |
66 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA112053593 rs903031887 |
67 | D>Y | No |
ClinGen TOPMed |
|
|
CA358928800 rs1280409151 |
68 | R>G | No |
ClinGen TOPMed |
|
|
CA358928791 rs1301324218 |
68 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1561201923 CA358928689 |
71 | A>G | No |
ClinGen Ensembl |
|
|
rs772290548 CA3159882 |
73 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA358928623 rs1331970052 |
73 | A>V | No |
ClinGen gnomAD |
|
|
CA358928557 rs1209984769 |
76 | L>M | No |
ClinGen TOPMed |
|
|
CA3159880 rs766468700 |
78 | L>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159878 rs771028495 |
79 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358928425 rs1191199211 |
81 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
rs776195245 CA3159862 |
83 | G>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA112052301 rs776195245 |
83 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772452819 CA3159861 |
84 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs759700320 CA3159860 |
85 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA3159859 rs577853473 |
86 | H>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3159858 rs770996211 |
88 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs1561200671 CA358927542 |
88 | W>R | No |
ClinGen Ensembl |
|
|
CA358927518 rs1178485427 |
89 | S>C | No |
ClinGen TOPMed gnomAD |
|
|
CA358927501 rs1355493976 |
90 | P>A | No |
ClinGen gnomAD |
|
|
rs749504795 CA3159856 |
91 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs1486864126 CA358927461 |
92 | V>L | No |
ClinGen gnomAD |
|
|
CA112052227 rs373657946 |
93 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1210471742 CA358927346 |
95 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
CA358927344 rs1210471742 |
95 | D>V | No |
ClinGen TOPMed gnomAD |
|
|
CA358927297 rs1354733261 |
97 | K>T | No |
ClinGen gnomAD |
|
|
CA3159853 rs746797109 |
99 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1222194139 CA358927246 |
100 | P>L | No |
ClinGen gnomAD |
|
|
rs1349820490 CA358927222 |
104 | N>D | No |
ClinGen TOPMed |
|
|
rs1448422407 CA358927199 |
107 | S>P | No |
ClinGen gnomAD |
|
|
CA3159852 rs758243142 |
109 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA358927174 rs1310886697 |
110 | Q>H | No |
ClinGen gnomAD |
|
|
rs549674569 CA358925040 |
111 | D>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3159813 rs143725812 |
111 | D>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3159814 rs143725812 |
111 | D>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1259450618 CA358925014 |
115 | F>C | No |
ClinGen gnomAD |
|
|
CA112047679 rs898065054 |
115 | F>I | No |
ClinGen TOPMed |
|
|
rs1447945863 CA358924984 |
119 | H>R | No |
ClinGen gnomAD |
|
|
CA358924979 rs1394156706 |
120 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
CA112047660 rs1036740562 |
121 | I>V | No |
ClinGen gnomAD |
|
|
rs755359056 CA3159806 |
122 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs1580248508 CA358924950 |
124 | K>N | No |
ClinGen Ensembl |
|
|
rs1456628892 CA358924924 |
128 | I>M | No |
ClinGen TOPMed gnomAD |
|
|
CA358924912 rs1418573250 |
129 | P>L | No |
ClinGen gnomAD |
|
|
CA358924881 rs866105307 |
131 | R>L | No |
ClinGen TOPMed |
|
|
CA112047618 rs866105307 |
131 | R>Q | No |
ClinGen TOPMed |
|
|
CA358924871 rs1315591311 |
132 | S>N | No |
ClinGen TOPMed |
|
|
rs772550208 CA3159803 |
133 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA112044826 rs753921891 |
133 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs942373739 CA112044816 |
137 | T>A | No |
ClinGen Ensembl |
|
|
rs762780442 CA3159777 |
140 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358924565 rs1580239851 |
144 | G>D | No |
ClinGen Ensembl |
|
|
rs1580239845 CA358924541 |
145 | S>R | No |
ClinGen Ensembl |
|
|
CA358924535 rs1477986709 |
146 | G>R | No |
ClinGen gnomAD |
|
|
CA358924523 rs769851440 |
147 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs776185705 CA3159773 |
148 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA3159772 rs768005687 |
149 | T>N | No |
ClinGen ExAC gnomAD |
|
|
RCV000492996 rs1131691306 CA358924477 |
150 | P>S | No |
ClinGen ClinVar Ensembl dbSNP |
|
|
CA358924444 rs1350389003 |
152 | S>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA3159770 rs775062269 |
153 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs1233743579 CA358924359 |
158 | T>I | No |
ClinGen gnomAD |
|
|
rs1580239737 CA358924362 |
158 | T>S | No |
ClinGen Ensembl |
|
|
CA3159767 rs779435259 |
159 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358924296 rs1346987136 |
162 | G>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1346987136 CA358924298 |
162 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
rs749708919 CA3159766 |
162 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs1170378249 CA358924289 |
163 | D>H | No |
ClinGen TOPMed |
|
|
rs1307224239 CA358924039 |
165 | K>N | No |
ClinGen gnomAD |
|
|
rs772307008 CA112044774 |
165 | K>Q | No |
ClinGen Ensembl |
|
|
rs374691561 CA3159765 |
167 | A>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs371228193 CA3159764 |
167 | A>V | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1580239579 CA358924025 |
168 | A>S | No |
ClinGen Ensembl |
|
|
rs1580239567 CA358924017 |
169 | K>R | No |
ClinGen Ensembl |
|
|
rs1580239554 CA358924013 |
170 | L>M | No |
ClinGen Ensembl |
|
|
rs1580239536 CA358924005 |
171 | A>G | No |
ClinGen Ensembl |
|
|
rs1561192318 CA358923998 |
172 | P>L | No |
ClinGen Ensembl |
|
|
CA358923987 rs1328220969 |
174 | I>F | No |
ClinGen TOPMed |
|
|
CA358923988 rs1328220969 |
174 | I>V | No |
ClinGen TOPMed |
|
|
CA358923974 rs1580239482 |
176 | L>S | No |
ClinGen Ensembl |
|
|
rs1189169482 CA358923955 |
178 | M>I | No |
ClinGen gnomAD |
|
|
CA358923938 rs1255668243 |
181 | P>S | No |
ClinGen gnomAD |
|
|
rs765318874 CA358923928 |
183 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1447674398 CA358923918 |
184 | K>N | No |
ClinGen gnomAD |
|
|
CA3159758 rs761837498 |
185 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs1370714820 CA358923892 |
188 | A>D | No |
ClinGen TOPMed |
|
|
rs959658377 CA112044710 |
189 | Q>R | No |
ClinGen Ensembl |
|
|
rs763670084 CA3159756 |
190 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs369885925 CA112044709 |
190 | F>L | No |
ClinGen ESP |
|
|
rs794729096 CA335483 RCV000183694 |
191 | N>K | No |
ClinGen ClinVar Ensembl dbSNP |
|
|
rs1343442539 CA358923859 |
193 | P>L | No |
ClinGen TOPMed |
|
|
rs1300421675 CA358923862 |
193 | P>S | No |
ClinGen TOPMed |
|
|
rs760087085 CA358923835 |
196 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159753 rs771679939 |
199 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs746279543 CA3159752 |
200 | D>H | No |
ClinGen ExAC gnomAD |
|
|
CA3159751 rs774719040 |
203 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358923723 rs1399455647 |
204 | E>G | No |
ClinGen gnomAD |
|
|
CA358923712 rs1260924667 |
205 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA112044691 rs1021010073 |
208 | G>D | No |
ClinGen Ensembl |
|
|
CA358923652 rs1388637855 |
209 | Q>E | No |
ClinGen gnomAD |
|
|
CA358923630 rs1190214935 |
210 | V>F | No |
ClinGen TOPMed |
|
|
rs1248601284 CA358923560 |
215 | G>E | No |
ClinGen TOPMed |
|
|
rs1448724655 CA358923540 |
216 | E>V | No |
ClinGen TOPMed |
|
|
rs1475886457 CA358923508 |
218 | P>L | No |
ClinGen gnomAD |
|
|
rs150809809 CA3159749 |
218 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358923519 rs150809809 |
218 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375743721 CA3159748 |
220 | M>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358923476 rs375743721 |
220 | M>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358923117 rs1175762732 |
225 | A>T | No |
ClinGen Ensembl |
|
|
CA358923029 rs1356446915 |
229 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1356446915 CA358923027 |
229 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1443404539 CA358923034 |
229 | P>T | No |
ClinGen gnomAD |
|
|
CA358923013 rs1440043894 COSM1738955 |
230 | E>K | NS [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA3159723 rs777812739 |
231 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs751273771 CA3159719 |
235 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159716 rs773433295 |
236 | M>L | No |
ClinGen ExAC gnomAD |
|
|
rs770135681 CA3159715 |
237 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA3159712 rs775988516 |
241 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159713 rs768909650 COSM1220091 |
241 | R>W | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs374935162 CA3159710 |
244 | P>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1050946476 CA112043764 |
246 | Q>K | No |
ClinGen Ensembl |
|
|
rs1375808528 CA358922708 |
247 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA3159709 rs777436264 |
247 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs755863715 CA3159708 |
248 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1482521322 CA358922652 |
251 | G>S | No |
ClinGen gnomAD |
|
|
rs1257789806 CA358922599 |
253 | F>L | No |
ClinGen gnomAD |
|
|
CA358922589 rs1212344585 |
254 | R>I | No |
ClinGen gnomAD |
|
|
CA358922571 rs1254946691 |
255 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs751026139 CA3159705 |
258 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA3159702 rs750021846 |
262 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358922403 rs1580236510 |
262 | D>V | No |
ClinGen Ensembl |
|
|
CA3159701 rs765723501 |
263 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA358921472 rs1193206985 |
266 | D>N | No |
ClinGen gnomAD |
|
|
CA3159683 rs539118406 |
267 | R>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3159677 rs767518283 |
272 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs776026329 CA3159678 |
272 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA3159675 rs759639015 |
273 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs759639015 CA358921375 |
273 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs774596253 CA3159674 |
275 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs1371727157 CA358921323 |
276 | A>V | No |
ClinGen gnomAD |
|
|
rs1384878275 CA358921307 |
277 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA358921293 rs747992902 |
278 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs747992902 CA3159673 |
278 | V>E | No |
ClinGen ExAC gnomAD |
|
|
CA358921277 rs1167476323 |
280 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
rs764788987 CA112042579 |
283 | G>D | No |
ClinGen Ensembl |
|
|
CA112042574 rs574011141 |
284 | G>C | No |
ClinGen ExAC gnomAD |
|
|
rs778768787 CA3159667 |
284 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs574011141 CA3159668 |
284 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA112042571 rs1002967178 |
285 | S>* | No |
ClinGen TOPMed |
|
|
rs1002967178 CA358921188 |
285 | S>L | No |
ClinGen TOPMed |
|
|
rs753475862 CA3159665 |
287 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA3159663 rs756453272 |
288 | A>E | No |
ClinGen ExAC gnomAD |
|
|
CA358921144 rs756453272 |
288 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs1561189423 CA358921153 |
288 | A>T | No |
ClinGen Ensembl |
|
|
rs768037463 CA3159661 |
289 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs1187819272 CA358921103 |
291 | M>I | No |
ClinGen gnomAD |
|
|
rs200921332 CA3159660 |
292 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs200921332 CA358921089 |
292 | P>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs763164171 CA358921018 |
296 | K>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159657 rs763164171 |
296 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1738978 rs768354891 CA3159655 |
297 | C>F | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA3159654 rs775360491 |
298 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA3159653 rs775360491 |
298 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs1580233099 CA358920965 |
299 | S>R | No |
ClinGen Ensembl |
|
|
RCV000620687 CA112042510 rs1034968896 |
299 | S>R | No |
ClinGen ClinVar TOPMed dbSNP |
|
|
CA3159652 rs745737342 |
300 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA358920964 rs1171370198 |
300 | G>S | No |
ClinGen gnomAD |
|
|
rs1364726114 CA358920918 |
302 | V>A | No |
ClinGen gnomAD |
|
|
rs945755028 CA112040611 |
303 | G>S | No |
ClinGen TOPMed |
|
|
CA358919917 rs1210309583 |
304 | A>G | No |
ClinGen gnomAD |
|
|
rs771699213 CA3159637 |
306 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774383499 CA358919858 |
308 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs779866944 CA3159636 |
308 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774383499 CA3159635 |
308 | A>V | No |
ClinGen ExAC gnomAD |
|
|
RCV000087222 rs483352737 CA229146 |
309 | R>W | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
rs1388328817 CA358919837 |
310 | D>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1388328817 CA358919834 |
310 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs747696179 CA3159632 |
311 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA112040570 rs1002047690 |
312 | Y>H | No |
ClinGen TOPMed |
|
|
CA358919786 rs144286715 |
313 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3159631 rs144286715 |
313 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs750492492 CA3159627 |
315 | P>H | No |
ClinGen ExAC gnomAD |
|
|
rs750492492 CA3159626 |
315 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs780511861 CA3159628 |
315 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs780511861 CA3159629 |
315 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA358919724 rs1248527723 |
317 | C>G | No |
ClinGen gnomAD |
|
|
CA3159625 rs765177053 |
317 | C>W | No |
ClinGen ExAC gnomAD |
|
|
rs1335155567 CA358919709 |
318 | F>C | No |
ClinGen TOPMed |
|
|
CA358919697 rs756047162 |
319 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1222033564 CA358919667 |
321 | A>T | No |
ClinGen gnomAD |
|
|
rs774470984 CA3159620 |
322 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159621 rs774470984 |
322 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766415797 CA3159619 |
325 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA358919560 rs1228328230 |
327 | L>V | No |
ClinGen TOPMed |
|
|
CA358919539 rs1299231345 |
328 | K>R | No |
ClinGen gnomAD |
|
|
CA358919498 rs1365195566 |
330 | K>N | No |
ClinGen gnomAD |
|
|
rs1433516310 CA358919505 |
330 | K>T | No |
ClinGen gnomAD |
|
|
rs772792268 CA3159617 |
332 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA3159616 rs555694674 |
333 | F>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs149332321 CA3159614 |
335 | I>K | No |
ClinGen ESP ExAC gnomAD |
|
|
rs149332321 CA3159613 |
335 | I>T | No |
ClinGen ESP ExAC gnomAD |
|
|
CA358919415 rs1392077999 |
335 | I>V | No |
ClinGen gnomAD |
|
|
CA3159610 rs535502739 |
337 | G>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs368815493 CA3159608 |
342 | E>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3159605 rs764191858 |
344 | H>Y | No |
ClinGen ExAC |
|
|
rs1342006001 CA358919265 |
346 | R>G | No |
ClinGen gnomAD |
|
|
CA3159602 rs762986959 |
346 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762986959 CA3159601 |
346 | R>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs537302602 CA112040421 |
347 | A>P | No |
ClinGen Ensembl |
|
|
rs772981250 CA3159600 |
348 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs764823333 CA358919253 |
348 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761204525 CA3159598 |
351 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA358919230 rs1372648010 |
352 | P>S | No |
ClinGen gnomAD |
|
|
rs746610846 CA3159595 |
353 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs768290059 CA3159596 |
353 | E>K | No |
ClinGen ExAC |
|
|
rs894305827 CA112040381 |
355 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
rs894305827 CA358919209 |
355 | Y>F | No |
ClinGen TOPMed gnomAD |
|
|
CA358919212 rs1173227868 |
355 | Y>H | No |
ClinGen TOPMed |
|
|
rs920811532 CA112040370 |
357 | T>A | No |
ClinGen Ensembl |
|
|
rs775841507 CA3159594 |
357 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3159592 rs746412079 |
361 | Y>H | No |
ClinGen ExAC gnomAD |
No associated diseases with Q53GG5
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| adherens junction | A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| filamentous actin | A two-stranded helical polymer of the protein actin. |
| stress fiber | A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber. |
| Z disc | Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin binding | Binding to monomeric or multimeric forms of actin, including actin filaments. |
| metal ion binding | Binding to a metal ion. |
| muscle alpha-actinin binding | Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| actin cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| heart development | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
| muscle structure development | The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3SYZ8 | PDLIM3 | PDZ and LIM domain protein 3 | Bos taurus (Bovine) | PR |
| P49024 | PXN | Paxillin | Gallus gallus (Chicken) | PR |
| Q9PU47 | PDLIM3 | PDZ and LIM domain protein 3 | Gallus gallus (Chicken) | PR |
| P49023 | PXN | Paxillin | Homo sapiens (Human) | PR |
| O43294 | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein | Homo sapiens (Human) | PR |
| Q62219 | Tgfb1i1 | Transforming growth factor beta-1-induced transcript 1 protein | Mus musculus (Mouse) | PR |
| Q8VI36 | Pxn | Paxillin | Mus musculus (Mouse) | PR |
| O70209 | Pdlim3 | PDZ and LIM domain protein 3 | Mus musculus (Mouse) | PR |
| Q6QGC0 | PDLIM3 | PDZ and LIM domain protein 3 | Sus scrofa (Pig) | PR |
| Q66H76 | Pxn | Paxillin | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPQTVILPGP | APWGFRLSGG | IDFNQPLVIT | RITPGSKAAA | ANLCPGDVIL | AIDGFGTESM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| THADAQDRIK | AAAHQLCLKI | DRGETHLWSP | QVSEDGKAHP | FKINLESEPQ | DGNYFEHKHN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRPKPFVIPG | RSSGCSTPSG | IDCGSGRSTP | SSVSTVSTIC | PGDLKVAAKL | APNIPLEMEL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PGVKIVHAQF | NTPMQLYSDD | NIMETLQGQV | STALGETPLM | SEPTASVPPE | SDVYRMLHDN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RNEPTQPRQS | GSFRVLQGMV | DDGSDDRPAG | TRSVRAPVTK | VHGGSGGAQR | MPLCDKCGSG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IVGAVVKARD | KYRHPECFVC | ADCNLNLKQK | GYFFIEGELY | CETHARARTK | PPEGYDTVTL |
| YPKA |