D3ZRW8
Gene name |
Etnk2 |
Protein name |
Ethanolamine kinase 2 |
Names |
EKI 2, Ethanolamine kinase-like protein |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:360843 |
EC number |
2.7.1.82: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for D3ZRW8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-D3ZRW8-F1 | Predicted | AlphaFoldDB |
No variants for D3ZRW8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for D3ZRW8 | |||||
No associated diseases with D3ZRW8
No regional properties for D3ZRW8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for D3ZRW8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.82 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ethanolamine kinase activity | Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| in utero embryonic development | The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. |
| multicellular organism growth | The increase in size or mass of an entire multicellular organism, as opposed to cell growth. |
| phosphatidylethanolamine biosynthetic process | The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| placenta development | The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. |
| post-embryonic development | The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P20485 | CKI1 | Choline kinase | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P54352 | eas | Ethanolamine kinase | Drosophila melanogaster (Fruit fly) | PR |
| Q9HBU6 | ETNK1 | Ethanolamine kinase 1 | Homo sapiens (Human) | PR |
| P35790 | CHKA | Choline kinase alpha | Homo sapiens (Human) | PR |
| O54804 | Chka | Choline kinase alpha | Mus musculus (Mouse) | PR |
| Q9D4V0 | Etnk1 | Ethanolamine kinase 1 | Mus musculus (Mouse) | PR |
| A7MCT6 | Etnk2 | Ethanolamine kinase 2 | Mus musculus (Mouse) | PR |
| Q01134 | Chka | Choline kinase alpha | Rattus norvegicus (Rat) | PR |
| Q8L518 | At1g74320 | Probable choline kinase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVPPSAPVP | CSPFYLRRQE | ACPQCSWSME | EKAVASASCW | EPPGPPRAAV | PCFAIAVDQD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DILPGALRLI | RELRPHWKPE | QVRTKRFKDG | ITNKLLACYV | EEDMRDCVLV | RVYGEWTELL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VDRENEIRNF | QLLRAHGCAP | KLYCTFQNGL | CYEYMQGVAL | GPEHIREPQL | FRLIALEMAK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IHTIHANGSL | PKPTLWHKMH | RYFTLVKDEI | SPSLSADVPK | VEVLEQELAW | LKEHLSQLDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PVVFCHNDLL | CKNIIYDSDK | GHVRFIDYEY | AGYNYQAFDI | GNHFNEFAGV | NEVDYCRYPA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| REIQLQWLRY | YLEAQKGTAA | SPREVERLYA | QVNKFALASH | FFWALWALIQ | NQYSTINFDF |
| 370 | 380 | ||||
| LRYAVIRFNQ | YFKVKPQVSA | LEMPK |