Q9ZW30
Gene name |
GSTU1 (GST19, At2g29490, F16P2.13) |
Protein name |
Glutathione S-transferase U1 |
Names |
AtGSTU1, GST class-tau member 1, Glutathione S-transferase 19 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G29490 |
EC number |
2.5.1.18: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZW30
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZW30-F1 | Predicted | AlphaFoldDB |
29 variants for Q9ZW30
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_12632318_C_T | 15 | A>T | No | 1000Genomes | |
| tmp_2_12632317_G_A | 15 | A>V | No | 1000Genomes | |
| tmp_2_12632240_G_C | 41 | P>A | No | 1000Genomes | |
| ENSVATH01923885 | 45 | P>S | No | 1000Genomes | |
| tmp_2_12632186_C_T | 59 | V>I | No | 1000Genomes | |
| tmp_2_12632156_C_T | 69 | E>K | No | 1000Genomes | |
| tmp_2_12632131_A_G | 77 | I>T | No | 1000Genomes | |
| tmp_2_12632129_C_T | 78 | D>N | No | 1000Genomes | |
| ENSVATH01923883 | 84 | S>N | No | 1000Genomes | |
| ENSVATH01923882 | 88 | P>S | No | 1000Genomes | |
| ENSVATH05624424 | 91 | P>R | No | 1000Genomes | |
| ENSVATH13468174 | 96 | M>V | No | 1000Genomes | |
| tmp_2_12631927_C_A | 114 | R>M | No | 1000Genomes | |
| ENSVATH05624421 | 124 | E>D | No | 1000Genomes | |
| ENSVATH00253697 | 135 | M>T | No | 1000Genomes | |
| tmp_2_12631849_T_C | 140 | E>G | No | 1000Genomes | |
| ENSVATH05624420 | 145 | D>Y | No | 1000Genomes | |
| tmp_2_12631823_C_A | 149 | G>C | No | 1000Genomes | |
| ENSVATH01923877 | 162 | M>I | No | 1000Genomes | |
| tmp_2_12631765_G_T | 168 | A>D | No | 1000Genomes | |
| ENSVATH01923876 | 172 | K>E | No | 1000Genomes | |
| ENSVATH13468152 | 172 | K>I | No | 1000Genomes | |
| ENSVATH05624418 | 174 | I>T | No | 1000Genomes | |
| ENSVATH05624417 | 199 | A>T | No | 1000Genomes | |
| ENSVATH05624416 | 199 | A>V | No | 1000Genomes | |
| ENSVATH01923873 | 202 | G>E | No | 1000Genomes | |
| tmp_2_12631624_G_T | 215 | T>N | No | 1000Genomes | |
| ENSVATH13468151 | 223 | S>F | No | 1000Genomes | |
| tmp_2_12631597_G_A | 224 | A>V | No | 1000Genomes |
No associated diseases with Q9ZW30
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.18 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutathione transferase activity | Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| glutathione metabolic process | The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| toxin catabolic process | The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P78417 | GSTO1 | Glutathione S-transferase omega-1 | Homo sapiens (Human) | PR |
| O09131 | Gsto1 | Glutathione S-transferase omega-1 | Mus musculus (Mouse) | PR |
| Q9WVL0 | Gstz1 | Maleylacetoacetate isomerase | Mus musculus (Mouse) | PR |
| Q9N1F5 | GSTO1 | Glutathione S-transferase omega-1 | Sus scrofa (Pig) | PR |
| Q9Z339 | Gsto1 | Glutathione S-transferase omega-1 | Rattus norvegicus (Rat) | PR |
| P46421 | GSTU5 | Glutathione S-transferase U5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FUS9 | GSTU18 | Glutathione S-transferase U18 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEKEESVKL | LGFWASPFSR | RVEMALKLKG | VPYEYLEEDL | PNKTPLLLEL | NPLHKKVPVL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VHNDKILLES | HLILEYIDQT | WKNSPILPQD | PYEKAMARFW | AKFIDDQILT | LGFRSLVKAE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGREVAIEET | RELLMFLEKE | VTGKDFFGGK | TIGFLDMIAG | SMIPFCLARL | WKGIGIDMIP |
| 190 | 200 | 210 | 220 | ||
| EEKFPELNRW | IKNLEEVEAV | RGCIPPREKQ | IERMTKIAET | IKSA |