Q9FUS9
Gene name |
GSTU18 (GST29, At1g10360, F14N23.24) |
Protein name |
Glutathione S-transferase U18 |
Names |
AtGSTU18, GST class-tau member 18, Glutathione S-transferase 29 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G10360 |
EC number |
2.5.1.18: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FUS9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FUS9-F1 | Predicted | AlphaFoldDB |
25 variants for Q9FUS9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04549170 | 2 | A>T | No | 1000Genomes | |
| tmp_1_3396769_G_C | 13 | A>G | No | 1000Genomes | |
| ENSVATH00015885 | 44 | L>M | No | 1000Genomes | |
| ENSVATH00015884 | 76 | D>N | No | 1000Genomes | |
| tmp_1_3396545_G_C | 88 | P>A | No | 1000Genomes | |
| ENSVATH13874867 | 94 | R>Q | No | 1000Genomes | |
| ENSVATH04549167 | 104 | I>M | No | 1000Genomes | |
| ENSVATH04549162 | 117 | T>K | No | 1000Genomes | |
| ENSVATH01031980 | 119 | Q>K | No | 1000Genomes | |
| ENSVATH01031979 | 121 | D>E | No | 1000Genomes | |
| ENSVATH04549161 | 122 | E>K | No | 1000Genomes | |
| ENSVATH13874803 | 128 | I>K | No | 1000Genomes | |
| ENSVATH13874802 | 129 | A>T | No | 1000Genomes | |
| ENSVATH00015882 | 136 | K>E | No | 1000Genomes | |
| tmp_1_3395988_C_A | 145 | C>F | No | 1000Genomes | |
| ENSVATH10902279 | 166 | S>T | No | 1000Genomes | |
| tmp_1_3395867_C_A | 185 | E>D | No | 1000Genomes | |
| tmp_1_3395851_G_T | 191 | L>I | No | 1000Genomes | |
| ENSVATH10902278 | 197 | R>P | No | 1000Genomes | |
| ENSVATH04549160 | 198 | F>L | No | 1000Genomes | |
| ENSVATH10902277 | 206 | P>S | No | 1000Genomes | |
| ENSVATH00015879 | 208 | M>L | No | 1000Genomes | |
| ENSVATH00015878 | 225 | R>P | No | 1000Genomes | |
| tmp_1_3395746_G_T | 226 | Q>K | No | 1000Genomes | |
| ENSVATH10902276 | 227 | A>T | No | 1000Genomes |
No associated diseases with Q9FUS9
4 regional properties for Q9FUS9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glutathione S-transferase, N-terminal | 4 - 83 | IPR004045 |
| domain | Glutathione S-transferase, C-terminal | 99 - 202 | IPR004046 |
| domain | Glutathione S-transferase, C-terminal-like | 90 - 221 | IPR010987 |
| domain | Glutathione S-transferases Tau, C-terminal alpha helical domain, plant | 91 - 221 | IPR045074 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.18 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutathione transferase activity | Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| glutathione metabolic process | The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. |
| toxin catabolic process | The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P78417 | GSTO1 | Glutathione S-transferase omega-1 | Homo sapiens (Human) | PR |
| O09131 | Gsto1 | Glutathione S-transferase omega-1 | Mus musculus (Mouse) | PR |
| Q9WVL0 | Gstz1 | Maleylacetoacetate isomerase | Mus musculus (Mouse) | PR |
| Q9N1F5 | GSTO1 | Glutathione S-transferase omega-1 | Sus scrofa (Pig) | PR |
| Q9Z339 | Gsto1 | Glutathione S-transferase omega-1 | Rattus norvegicus (Rat) | PR |
| P46421 | GSTU5 | Glutathione S-transferase U5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZW30 | GSTU1 | Glutathione S-transferase U1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATEDVKLIG | SWASVYVMRA | RIALHLKSIS | YEFLQETYGS | KSELLLKSNP | VHKKMPVLIH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ADKPVCESNI | IVHYIDEAWN | SSGPSILPSH | PYDRAIARFW | AAYIDDQWFI | SVRSILTAQG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEEKKAAIAQ | VEERTKLLEK | AFNDCSQGKP | FFNGDHIGYL | DIALGSFLGW | WRVVELDANH |
| 190 | 200 | 210 | 220 | ||
| KFLDETKTPS | LVKWAERFCD | DPAVKPIMPE | ITKLAEFARK | LFPKRQA |