AiPD: Autoinhibited Protein Database

Gene name	ACO1 (At2g19590, F3P11.19)
Protein name	1-aminocyclopropane-1-carboxylate oxidase 1
Names	ACC oxidase 1, AtACO1
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT2G19590
EC number	1.14.17.4: With reduced ascorbate as one donor, and incorporation of one atom of oxygen
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

37-115 (Predicted disordered autoinhibitory region) PR

37-115 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9ZUN4-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH13284472	5	K>N	No	1000Genomes
ENSVATH07884333	6	E>D	No	1000Genomes
ENSVATH05535203	9	M>I	No	1000Genomes
ENSVATH13284470	10	E>Q	No	1000Genomes
ENSVATH01845827	21	G>E	No	1000Genomes
tmp_2_8477272_A_T	28	M>K	No	1000Genomes
tmp_2_8477273_T_C	28	M>V	No	1000Genomes
tmp_2_8477270_A_T	29	S>T	No	1000Genomes
tmp_2_8477125_A_C	49	D>E	No	1000Genomes
tmp_2_8477087_G_A	62	S>F	No	1000Genomes
tmp_2_8477043_T_A	77	M>L	No	1000Genomes
ENSVATH05535199	85	K>I	No	1000Genomes
tmp_2_8476820_T_C	118	T>A	No	1000Genomes
ENSVATH05535197	123	V>I	No	1000Genomes
tmp_2_8476793_G_A	127	H>Y	No	1000Genomes
ENSVATH13284461	133	L>F	No	1000Genomes
ENSVATH13284461	133	L>I	No	1000Genomes
ENSVATH13284459	136	L>V	No	1000Genomes
ENSVATH05535196	138	C>F	No	1000Genomes
ENSVATH05535196	138	C>S	No	1000Genomes
ENSVATH13284458	149	M>I	No	1000Genomes
ENSVATH13284440	196	Q>E	No	1000Genomes
tmp_2_8476559_C_T	205	D>N	No	1000Genomes
tmp_2_8476550_A_T,C	208	W>G	No	1000Genomes
tmp_2_8476550_A_T,C	208	W>R	No	1000Genomes
ENSVATH01845823	216	N>K	No	1000Genomes
ENSVATH05535195	218	T>P	No	1000Genomes
ENSVATH14521485	222	N>Y	No	1000Genomes
tmp_2_8476448_C_T	242	V>I	No	1000Genomes
tmp_2_8476394_C_T	260	A>T	No	1000Genomes
ENSVATH13284438	264	I>K	No	1000Genomes
ENSVATH13284439	264	I>L	No	1000Genomes
tmp_2_8476369_G_A	268	A>V	No	1000Genomes
ENSVATH14521474	275	S>N	No	1000Genomes
ENSVATH13284436	275	S>R	No	1000Genomes
ENSVATH00238963	296	P>S	No	1000Genomes
ENSVATH05535193	305	G>R	No	1000Genomes
tmp_2_8476246_G_T	309	S>*	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9ZUN4

		Description
EC Number	1.14.17.4	With reduced ascorbate as one donor, and incorporation of one atom of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
No GO annotations for cellular component

Name	Definition
1-aminocyclopropane-1-carboxylate oxidase activity	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene.
L-ascorbic acid binding	Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
metal ion binding	Binding to a metal ion.

Name	Definition
cellular response to fatty acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
cellular response to nitric oxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
cellular response to potassium ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.
defense response	Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
ethylene biosynthetic process	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P41213	A2	Leucoanthocyanidin dioxygenase	Zea mays (Maize)	PR
Q8H1S4	At1g06650	1-aminocyclopropane-1-carboxylate oxidase homolog 3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q96330	FLS1	Flavonol synthase/flavanone 3-hydroxylase	Arabidopsis thaliana (Mouse-ear cress)	PR
F4KAS1	FLS4	Probable flavonol synthase 4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q0WPW4	At1g77330	1-aminocyclopropane-1-carboxylate oxidase 5	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9C899	F6'H2	Feruloyl CoA ortho-hydroxylase 2	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FFQ5	FLS3	Flavonol synthase 3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FZ21	GA2OX6	Gibberellin 2-beta-dioxygenase 6	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9ZTA3	AOP1	Probable 2-oxoglutarate-dependent dioxygenase AOP1	Arabidopsis thaliana (Mouse-ear cress)	PR