Q9FZ21

PR
Gene name
GA2OX6 (At1g02400, T6A9.9)
Protein name
Gibberellin 2-beta-dioxygenase 6
Names
GA 2-oxidase 6, Gibberellin 2-beta-hydroxylase 6, Gibberellin 2-oxidase 6
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G02400
EC number
1.14.11.13: With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FZ21

Entry ID Method Resolution Chain Position Source
AF-Q9FZ21-F1 Predicted AlphaFoldDB

12 variants for Q9FZ21

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10475610 3 L>W No 1000Genomes
tmp_1_486994_A_C 11 T>P No 1000Genomes
ENSVATH07501075 16 T>R No 1000Genomes
ENSVATH01005135 21 E>D No 1000Genomes
ENSVATH04507734 25 P>S No 1000Genomes
ENSVATH01005136 40 K>N No 1000Genomes
ENSVATH01005137 47 V>G No 1000Genomes
ENSVATH04507761 258 V>G No 1000Genomes
tmp_1_489293_C_A 298 P>T No 1000Genomes
tmp_1_489296_A_G 299 R>G No 1000Genomes
tmp_1_489298_A_C 299 R>S No 1000Genomes
ENSVATH10475937 319 D>Y No 1000Genomes

No associated diseases with Q9FZ21

No regional properties for Q9FZ21

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FZ21

Functions

Description
EC Number 1.14.11.13 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
C-19 gibberellin 2-beta-dioxygenase activity Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.
dioxygenase activity Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products. [DOI:10.1016/S0040-4020(03)00944-X, GOC:bf]
metal ion binding Binding to a metal ion.

4 GO annotations of biological process

Name Definition
gibberellin biosynthetic process The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
gibberellin catabolic process The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
response to red or far red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P41213 A2 Leucoanthocyanidin dioxygenase Zea mays (Maize) PR
Q8H1S4 At1g06650 1-aminocyclopropane-1-carboxylate oxidase homolog 3 Arabidopsis thaliana (Mouse-ear cress) PR
F4KAS1 FLS4 Probable flavonol synthase 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q0WPW4 At1g77330 1-aminocyclopropane-1-carboxylate oxidase 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q96330 FLS1 Flavonol synthase/flavanone 3-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9C899 F6'H2 Feruloyl CoA ortho-hydroxylase 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FFQ5 FLS3 Flavonol synthase 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZTA3 AOP1 Probable 2-oxoglutarate-dependent dioxygenase AOP1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUN4 ACO1 1-aminocyclopropane-1-carboxylate oxidase 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVLPSSTPLQ TTGKKTISSP EYNFPVIDFS LNDRSKLSEK IVKACEVNGF FKVINHGVKP
70 80 90 100 110 120
EIIKRFEHEG EEFFNKPESD KLRAGPASPF GYGCKNIGFN GDLGELEYLL LHANPTAVAD
130 140 150 160 170 180
KSETISHDDP FKFSSATNDY IRTVRDLACE IIDLTIENLW GQKSSEVSEL IRDVRSDSIL
190 200 210 220 230 240
RLNHYPPAPY ALSGVGQIGF GEHSDPQILT VLRSNDVDGL EICSRDGLWI PIPSDPTCFF
250 260 270 280 290 300
VLVGDCLQAL TNGRFTSVRH RVLANTAKKP RMSAMYFAAP PLEAKISPLP KMVSPENPRR
310 320
YNSFTWGDYK KATYSLRLDV PRLEFFKTL