Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8H1S4

Entry ID Method Resolution Chain Position Source
AF-Q8H1S4-F1 Predicted AlphaFoldDB

33 variants for Q8H1S4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10708024 3 M>V No 1000Genomes
tmp_1_2035919_T_G 4 M>R No 1000Genomes
ENSVATH01019293 8 P>H No 1000Genomes
tmp_1_2035936_T_A 10 F>I No 1000Genomes
ENSVATH01019294 11 D>Y No 1000Genomes
tmp_1_2035948_A_G 14 S>G No 1000Genomes
ENSVATH10708085 31 D>E No 1000Genomes
tmp_1_2036034_T_A 42 H>Q No 1000Genomes
ENSVATH10708087 84 I>T No 1000Genomes
ENSVATH01019296 91 A>T No 1000Genomes
ENSVATH01019297 92 A>E No 1000Genomes
tmp_1_2036224_C_T 106 L>F No 1000Genomes
ENSVATH04531056 121 E>K No 1000Genomes
tmp_1_2036280_A_T 124 Q>H No 1000Genomes
tmp_1_2036279_A_C 124 Q>P No 1000Genomes
ENSVATH10708089 136 S>N No 1000Genomes
tmp_1_2036354_G_C 149 S>T No 1000Genomes
ENSVATH01019298 152 A>T No 1000Genomes
ENSVATH01019299 153 A>S No 1000Genomes
ENSVATH13858218 162 T>A No 1000Genomes
ENSVATH10708092 178 R>M No 1000Genomes
tmp_1_2036553_G_A 189 M>I No 1000Genomes
ENSVATH04531059 203 L>I No 1000Genomes
ENSVATH10708094 209 H>L No 1000Genomes
ENSVATH04531061 268 D>N No 1000Genomes
tmp_1_2036938_A_G 288 T>A No 1000Genomes
tmp_1_2036946_C_A 290 D>E No 1000Genomes
tmp_1_2036977_G_A 301 A>T No 1000Genomes
ENSVATH10708157 343 E>D No 1000Genomes
tmp_1_2037107_C_T 344 T>I No 1000Genomes
tmp_1_2037164_C_A 363 A>D No 1000Genomes
ENSVATH10708158 367 F>V No 1000Genomes
ENSVATH04531067 368 K>T No 1000Genomes

No associated diseases with Q8H1S4

1 regional properties for Q8H1S4

Type Name Position InterPro Accession
domain Septin-type guanine nucleotide-binding (G) domain 47 - 318 IPR030379

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P41213 A2 Leucoanthocyanidin dioxygenase Zea mays (Maize) PR
Q9FZ21 GA2OX6 Gibberellin 2-beta-dioxygenase 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q0WPW4 At1g77330 1-aminocyclopropane-1-carboxylate oxidase 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUN4 ACO1 1-aminocyclopropane-1-carboxylate oxidase 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZTA3 AOP1 Probable 2-oxoglutarate-dependent dioxygenase AOP1 Arabidopsis thaliana (Mouse-ear cress) PR
Q96330 FLS1 Flavonol synthase/flavanone 3-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9FFQ5 FLS3 Flavonol synthase 3 Arabidopsis thaliana (Mouse-ear cress) PR
F4KAS1 FLS4 Probable flavonol synthase 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C899 F6'H2 Feruloyl CoA ortho-hydroxylase 2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEMMKIDPLF DRASELKAFD ETKTGVKGLV DSGVSQVPRI FHHPTVKLST PKPLPSDLLH
70 80 90 100 110 120
LKTIPTIDLG GRDFQDAIKR NNAIEEIKEA AAKWGFFQVI NHGVSLELLE KMKKGVRDFH
130 140 150 160 170 180
EQSQEVRKEF YSRDFSRRFL YLSNFDLFSS PAANWRDTFS CTMAPDTPKP QDLPEICRDI
190 200 210 220 230 240
MMEYSKQVMN LGKFLFELLS EALGLEPNHL NDMDCSKGLL MLSHYYPPCP EPDLTLGTSQ
250 260 270 280 290 300
HSDNSFLTVL LPDQIEGLQV RREGHWFDVP HVSGALIINI GDLLQLITND KFISLEHRVL
310 320 330 340 350 360
ANRATRARVS VACFFTTGVR PNPRMYGPIR ELVSEENPPK YRETTIKDYA TYFNAKGLDG
TSALLHFKI