Q0WPW4
Gene name |
At1g77330 (F2P24.4) |
Protein name |
1-aminocyclopropane-1-carboxylate oxidase 5 |
Names |
ACC oxidase 5, AtACO5 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G77330 |
EC number |
1.14.17.4: With reduced ascorbate as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0WPW4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0WPW4-F1 | Predicted | AlphaFoldDB |
24 variants for Q0WPW4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13825756 | 14 | E>K | No | 1000Genomes | |
| tmp_1_29064378_C_T | 24 | A>T | No | 1000Genomes | |
| tmp_1_29064226_T_A | 47 | K>M | No | 1000Genomes | |
| ENSVATH05160948 | 54 | D>E | No | 1000Genomes | |
| ENSVATH05160949 | 54 | D>V | No | 1000Genomes | |
| tmp_1_29064119_C_G | 83 | E>Q | No | 1000Genomes | |
| ENSVATH00146004 | 107 | N>K | No | 1000Genomes | |
| ENSVATH01548293 | 114 | E>V | No | 1000Genomes | |
| tmp_1_29063917_A_G | 119 | V>A | No | 1000Genomes | |
| ENSVATH14487778 | 129 | V>L | No | 1000Genomes | |
| tmp_1_29063857_C_T | 139 | G>D | No | 1000Genomes | |
| tmp_1_29063689_T_C | 195 | Y>C | No | 1000Genomes | |
| ENSVATH00146003 | 204 | G>S | No | 1000Genomes | |
| tmp_1_29063660_C_T | 205 | E>K | No | 1000Genomes | |
| tmp_1_29063641_G_C | 211 | P>R | No | 1000Genomes | |
| ENSVATH00146000 | 266 | A>T | No | 1000Genomes | |
| ENSVATH13825754 | 266 | A>V | No | 1000Genomes | |
| tmp_1_29063340_C_A | 267 | V>L | No | 1000Genomes | |
| tmp_1_29063336_G_T | 268 | A>E | No | 1000Genomes | |
| tmp_1_29063324_C_T | 272 | G>E | No | 1000Genomes | |
| tmp_1_29063307_G_A | 278 | P>S | No | 1000Genomes | |
| ENSVATH05160933 | 288 | V>I | No | 1000Genomes | |
| ENSVATH14487777 | 293 | K>T | No | 1000Genomes | |
| tmp_1_29063243_G_A | 299 | P>L | No | 1000Genomes |
No associated diseases with Q0WPW4
1 regional properties for Q0WPW4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | 42 - 52 | IPR001412 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.17.4 | With reduced ascorbate as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 1-aminocyclopropane-1-carboxylate oxidase activity | Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene. |
| dioxygenase activity | Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products. [DOI:10.1016/S0040-4020(03)00944-X, GOC:bf] |
| L-ascorbic acid binding | Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
| ethylene biosynthetic process | The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P41213 | A2 | Leucoanthocyanidin dioxygenase | Zea mays (Maize) | PR |
| Q8H1S4 | At1g06650 | 1-aminocyclopropane-1-carboxylate oxidase homolog 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4KAS1 | FLS4 | Probable flavonol synthase 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q96330 | FLS1 | Flavonol synthase/flavanone 3-hydroxylase | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C899 | F6'H2 | Feruloyl CoA ortho-hydroxylase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FFQ5 | FLS3 | Flavonol synthase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FZ21 | GA2OX6 | Gibberellin 2-beta-dioxygenase 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZTA3 | AOP1 | Probable 2-oxoglutarate-dependent dioxygenase AOP1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUN4 | ACO1 | 1-aminocyclopropane-1-carboxylate oxidase 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAIPVIDFSK | LNGEEREKTL | SEIARACEEW | GFFQLVNHGI | PLELLNKVKK | LSSDCYKTER |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEAFKTSNPV | KLLNELVQKN | SGEKLENVDW | EDVFTLLDHN | QNEWPSNIKE | TMGEYREEVR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLASKMMEVM | DENLGLPKGY | IKKAFNEGME | DGEETAFFGT | KVSHYPPCPH | PELVNGLRAH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TDAGGVVLLF | QDDEYDGLQV | LKDGEWIDVQ | PLPNAIVINT | GDQIEVLSNG | RYKSAWHRVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AREEGNRRSI | ASFYNPSYKA | AIGPAAVAEE | EGSEKKYPKF | VFGDYMDVYA | NQKFMPKEPR |
| FLAVKSL |