Q9ULS6
PR
Gene name |
KCNS2 (KIAA1144) |
Protein name |
Potassium voltage-gated channel subfamily S member 2 |
Names |
Delayed-rectifier K(+) channel alpha subunit 2, Voltage-gated potassium channel subunit Kv9.2 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:3788 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ULS6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ULS6-F1 | Predicted | AlphaFoldDB |
351 variants for Q9ULS6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs773390011 CA4821337 |
2 | T>N | No |
ClinGen ExAC gnomAD |
|
|
rs766499929 CA4821339 |
3 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371847502 rs766499929 |
3 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1156789529 CA371847530 |
7 | W>* | No |
ClinGen gnomAD |
|
|
rs199762721 CA4821341 |
7 | W>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA182738210 rs1024886858 |
8 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs767207753 CA4821343 |
9 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA4821342 rs767207753 |
9 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs777451821 CA182738216 |
10 | S>* | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 10 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs971244387 CA371847547 |
10 | S>P | No |
ClinGen TOPMed |
|
|
CA182738214 rs971244387 COSM343788 |
10 | S>T | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs777451821 CA4821345 |
10 | S>W | No |
ClinGen ExAC gnomAD |
|
|
rs778488316 CA4821348 |
11 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 14 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821350 rs769263958 |
14 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA371847577 rs1186787704 |
15 | E>Q | No |
ClinGen TOPMed |
|
|
rs140515528 CA4821356 |
16 | D>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4821354 rs773516630 |
16 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs144362730 CA4821358 CA4821359 |
17 | G>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs144362730 CA4821357 |
17 | G>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4821361 rs760414695 |
18 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA4821362 rs763909604 |
18 | E>V | No |
ClinGen ExAC gnomAD |
|
|
rs201468098 CA4821364 |
20 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA182738236 rs972833387 |
20 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA371847610 rs1326122049 |
21 | I>L | No |
ClinGen gnomAD |
|
|
CA371847629 rs1319307633 |
23 | V>A | No |
ClinGen TOPMed |
|
|
CA371847625 rs1239828977 |
23 | V>M | No |
ClinGen TOPMed |
|
|
rs781775868 CA4821368 |
26 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs748684605 CA4821369 |
27 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA182738244 rs933828984 |
27 | K>N | No |
ClinGen TOPMed |
|
|
CA371847664 rs1334567989 |
29 | R>W | No |
ClinGen gnomAD |
|
|
CA371847677 rs1275336080 |
31 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs943624688 CA182738245 |
31 | R>S | No |
ClinGen gnomAD |
|
|
CA371847684 rs1436279030 |
32 | S>W | No |
ClinGen gnomAD |
|
|
CA371847687 rs1203917754 |
33 | H>Y | No |
ClinGen gnomAD |
|
|
rs140159901 CA4821370 |
36 | L>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1480950741 CA371847710 |
37 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1184225176 CA371847712 |
37 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA371847729 rs1365533034 |
40 | E>K | No |
ClinGen TOPMed |
|
|
CA4821373 rs771255852 |
41 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1407855949 CA371847749 |
43 | L>V | No |
ClinGen gnomAD |
|
| TCGA novel | 48 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821377 rs758514346 |
52 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA182738257 rs911026515 |
52 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1586557402 CA371847845 |
58 | L>F | No |
ClinGen Ensembl |
|
|
rs1563599625 CA371847880 |
62 | Y>* | No |
ClinGen Ensembl |
|
| TCGA novel | 64 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 68 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821381 rs761366150 |
70 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA371847945 rs572431917 |
71 | F>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1309297540 CA371847941 |
71 | F>V | No |
ClinGen gnomAD |
|
|
CA4821383 rs749873859 |
72 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs1255341726 CA371847948 |
72 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1255341726 CA371847949 |
72 | D>Y | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 73 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA182738268 rs567295212 |
73 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA4821384 rs757872023 |
73 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371847955 rs567295212 |
73 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA371847962 rs1166929222 |
74 | N>S | No |
ClinGen gnomAD |
|
|
CA371847969 rs1419741727 |
75 | P>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
COSM257209 CA4821385 rs766014301 CA182738273 |
76 | E>D | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA371847982 rs1171136504 |
77 | L>P | No |
ClinGen gnomAD |
|
|
rs1415930880 CA371847997 |
79 | P>L | No |
ClinGen gnomAD |
|
|
rs1171041080 CA371847994 |
79 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA4821387 rs756745133 |
81 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA4821386 rs753185856 |
81 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA371848030 rs1271020015 |
84 | F>L | No |
ClinGen gnomAD |
|
|
rs778282146 CA4821388 |
87 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA4821389 rs749707358 |
90 | L>F | No |
ClinGen ExAC |
|
|
rs757398784 CA4821390 |
92 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA371848092 rs1452920968 |
93 | M>I | No |
ClinGen Ensembl |
|
|
CA371848087 rs1279704268 |
93 | M>K | No |
ClinGen gnomAD |
|
|
CA182738281 rs779927912 |
94 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA4821391 rs779149114 |
97 | C>R | No |
ClinGen ExAC gnomAD |
|
|
CA371848118 rs1398583859 |
98 | V>I | No |
ClinGen gnomAD |
|
|
rs1418980185 CA371848136 |
100 | S>F | No |
ClinGen TOPMed |
|
|
rs772074757 CA4821393 |
102 | S>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 104 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821396 COSM2792634 rs373045610 |
106 | E>K | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD |
|
rs1393940932 CA371848201 |
109 | G>C | No |
ClinGen gnomAD |
|
|
CA371848215 rs1174796565 |
111 | N>H | No |
ClinGen gnomAD |
|
|
rs1013751347 CA182738286 |
111 | N>K | No |
ClinGen TOPMed |
|
|
rs1383383175 CA371848244 |
115 | I>L | No |
ClinGen gnomAD |
|
|
rs1400510344 CA371848248 |
115 | I>T | No |
ClinGen gnomAD |
|
|
rs1391201111 CA371848287 |
120 | S>R | No |
ClinGen gnomAD |
|
|
rs144881255 CA4821399 |
121 | Y>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1302835506 CA371848298 |
122 | S>C | No |
ClinGen gnomAD |
|
|
CA4821400 rs772878262 |
124 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA371848322 rs1235464282 |
125 | G>D | No |
ClinGen gnomAD |
|
|
rs765976410 CA4821402 COSM1674021 |
126 | R>C | Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1215945422 CA371848329 |
126 | R>L | No |
ClinGen TOPMed |
|
| TCGA novel | 127 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756661331 CA4821404 |
128 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371848338 rs1284687712 |
128 | V>I | No |
ClinGen gnomAD |
|
|
rs1283072790 CA371848351 |
130 | P>T | No |
ClinGen TOPMed |
|
|
CA4821407 rs757602152 |
131 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821406 rs376045564 |
131 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA182738298 rs1024200511 |
132 | Q>K | No |
ClinGen TOPMed |
|
|
CA4821409 rs779150579 |
134 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs1470074390 CA371848388 |
135 | W>* | No |
ClinGen gnomAD |
|
|
rs1159570482 CA371848400 |
136 | D>E | No |
ClinGen gnomAD |
|
| TCGA novel | 137 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA371848418 rs541434350 |
139 | S>G | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA182738304 rs541434350 |
139 | S>R | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA371848439 rs1398828027 |
141 | Q>H | No |
ClinGen TOPMed |
|
|
rs1460111678 CA371848458 |
144 | T>A | No |
ClinGen gnomAD |
|
|
rs758675215 CA371848460 |
144 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA4821411 rs758675215 |
144 | T>N | No |
ClinGen ExAC gnomAD |
|
|
CA4821412 rs780101812 |
145 | T>M | No |
ClinGen ExAC gnomAD |
|
|
rs866829393 CA182738309 COSM1102900 |
149 | D>N | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1563599829 CA371848520 |
153 | A>V | No |
ClinGen Ensembl |
|
|
rs34615041 CA182738317 |
154 | F>V | No |
ClinGen Ensembl |
|
|
rs199526084 CA182738321 |
156 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4821417 rs769562533 |
156 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA4821416 rs748062861 |
156 | N>Y | No |
ClinGen ExAC gnomAD |
|
|
CA371848551 rs1488567981 |
158 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
CA371848549 rs1488567981 |
158 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs770749773 CA4821420 |
158 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs749919384 CA182738326 |
159 | S>C | No |
ClinGen TOPMed gnomAD |
|
|
rs749919384 CA371848557 |
159 | S>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1198961836 CA371848566 |
160 | K>N | No |
ClinGen Ensembl |
|
|
CA371848574 rs1183130669 |
161 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA4821422 rs759068889 |
162 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA4821423 COSM1458831 rs145156738 |
163 | G>R | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA4821427 rs765619596 |
167 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs987283877 CA182738337 |
168 | N>I | No |
ClinGen TOPMed |
|
|
rs987283877 CA371848615 |
168 | N>T | No |
ClinGen TOPMed |
|
|
CA371848622 rs1390786569 |
169 | F>Y | No |
ClinGen gnomAD |
|
|
rs1308589032 CA371848630 |
170 | R>H | Variant assessed as Somatic; 4.631e-05 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA371848632 rs1308589032 |
170 | R>L | No |
ClinGen gnomAD |
|
|
CA371848654 rs1260232955 |
174 | W>R | No |
ClinGen TOPMed |
|
|
CA371848657 rs1280450341 |
174 | W>S | No |
ClinGen TOPMed gnomAD |
|
|
rs750851877 CA182738339 |
176 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821428 rs750851877 |
176 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750851877 CA371848670 |
176 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371848674 rs1586557610 |
177 | L>P | No |
ClinGen Ensembl |
|
|
CA371848679 rs1586557612 |
178 | D>G | No |
ClinGen Ensembl |
|
|
rs1586557614 CA371848687 |
179 | N>T | No |
ClinGen Ensembl |
|
|
rs758587162 CA4821429 |
180 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs942498856 CA182738344 |
181 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1322013787 CA371848721 |
184 | V>A | No |
ClinGen gnomAD |
|
|
rs1338045934 CA371848725 |
185 | L>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1195697694 CA371848728 |
186 | S>G | No |
ClinGen gnomAD |
|
|
CA371848736 rs1271756572 |
187 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1246511291 CA371848737 |
187 | R>K | No |
ClinGen gnomAD |
|
|
CA371848747 rs1586557635 |
188 | V>G | No |
ClinGen Ensembl |
|
| TCGA novel | 190 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA371848769 rs1217558358 |
191 | I>N | No |
ClinGen TOPMed |
|
|
rs201122636 CA4821432 |
204 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs971300379 CA182738346 |
204 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA4821433 rs201740520 |
205 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 205 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 206 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA371848878 rs1254614285 |
208 | S>N | No |
ClinGen gnomAD |
|
|
CA371848888 rs1339769577 |
210 | P>T | No |
ClinGen TOPMed |
|
|
COSM1102902 CA4821436 rs138992941 |
211 | D>N | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA371848918 rs1170155388 |
214 | I>V | No |
ClinGen TOPMed |
|
|
CA4821437 rs749147597 |
215 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371848926 rs1462044926 |
215 | P>T | No |
ClinGen TOPMed |
|
|
CA182738355 rs925173886 |
216 | D>E | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 221 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770876236 CA4821438 |
221 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA4821439 rs774106966 |
222 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771554393 CA4821441 |
223 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774922579 CA4821442 |
224 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1235988192 CA371848985 |
224 | D>Y | No |
ClinGen TOPMed |
|
| TCGA novel | 225 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs762376533 CA4821443 |
226 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA371849016 rs1334947846 |
228 | E>D | No |
ClinGen TOPMed |
|
|
CA371849010 COSM3432668 rs1325431545 |
228 | E>K | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1276152493 CA371849024 |
229 | I>M | No |
ClinGen TOPMed gnomAD |
|
|
CA371849022 rs1228502968 |
229 | I>T | No |
ClinGen gnomAD |
|
|
rs1346414153 CA371849029 |
230 | V>A | No |
ClinGen gnomAD |
|
|
rs1226092983 CA371849026 |
230 | V>L | No |
ClinGen TOPMed |
|
|
rs917570715 CA182738366 |
231 | E>G | No |
ClinGen TOPMed |
|
|
rs910548275 CA371849038 |
232 | H>D | No |
ClinGen gnomAD |
|
|
CA182738368 rs910548275 |
232 | H>Y | No |
ClinGen gnomAD |
|
|
CA4821445 rs765702013 |
235 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371849069 rs1444114392 |
236 | A>V | No |
ClinGen TOPMed |
|
|
CA371849074 rs1374307438 |
237 | W>* | No |
ClinGen TOPMed |
|
|
CA371849095 rs1441866449 |
240 | F>L | No |
ClinGen TOPMed |
|
|
CA4821446 rs763254980 |
243 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA182738376 rs747283529 |
245 | R>S | No |
ClinGen Ensembl |
|
|
CA371849142 rs1185090151 |
247 | A>S | No |
ClinGen gnomAD |
|
|
CA4821448 rs751710987 |
253 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371849204 rs1190671679 |
256 | F>Y | No |
ClinGen gnomAD |
|
|
CA371849225 rs1586557724 |
259 | A>T | No |
ClinGen Ensembl |
|
|
CA4821450 rs781316152 |
260 | L>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 260 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA371849232 rs1452553524 |
260 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1426643052 CA371849248 |
262 | L>R | No |
ClinGen gnomAD |
|
|
rs778907852 CA182738384 |
265 | L>F | No |
ClinGen Ensembl |
|
|
CA371849277 rs1301304122 |
266 | M>I | No |
ClinGen gnomAD |
|
|
CA4821452 rs756060141 |
268 | I>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA182738386 rs756060141 |
268 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1102905 RCV000897754 CA4821454 rs142144460 |
269 | V>I | oesophagus endometrium [Cosmic] | No |
ClinGen cosmic curated ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
rs757047371 CA4821455 |
273 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821456 rs532560696 |
274 | T>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 276 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs775032317 CA4821459 |
278 | N>K | No |
ClinGen ExAC gnomAD |
|
|
rs746548261 CA4821460 |
279 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA371849367 rs773665267 |
282 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821462 rs773665267 |
282 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763452259 CA4821463 |
283 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs143746607 CA4821465 |
284 | T>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs759775317 CA4821467 |
285 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs1362786078 CA371849392 |
286 | T>A | No |
ClinGen Ensembl |
|
|
CA4821468 rs767684188 |
289 | N>T | No |
ClinGen ExAC gnomAD |
|
|
CA371849426 rs1351275452 |
291 | G>S | No |
ClinGen TOPMed |
|
|
CA4821471 rs764274573 |
293 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA182738413 rs909380214 |
293 | V>L | No |
ClinGen Ensembl |
|
|
rs1293532424 CA371849464 |
297 | L>P | No |
ClinGen gnomAD |
|
|
CA182738419 rs867677463 |
298 | R>M | No |
ClinGen Ensembl |
|
|
rs894124156 CA182738421 |
299 | L>P | No |
ClinGen Ensembl |
|
|
rs757324627 CA4821473 |
300 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821475 rs745687970 |
301 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs758043614 CA4821476 |
302 | I>F | No |
ClinGen ExAC |
|
|
CA4821478 rs200723055 |
304 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4821479 rs370705767 |
304 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA371849511 rs771492184 |
305 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs749779842 CA4821481 |
305 | I>V | No |
ClinGen ExAC |
|
|
rs141882203 CA4821483 |
307 | K>R | No |
ClinGen ESP ExAC |
|
|
rs1489452208 CA371849536 |
309 | A>V | No |
ClinGen gnomAD |
|
|
CA4821484 rs759771726 |
311 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs567674235 CA4821486 |
316 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs760969781 CA4821487 |
316 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA4821488 rs764260125 |
317 | S>Y | No |
ClinGen ExAC gnomAD |
|
|
rs754040509 CA4821489 |
319 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371849593 rs754040509 |
319 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1164928487 CA371849594 |
320 | A>T | No |
ClinGen gnomAD |
|
|
CA371849603 rs1468146854 |
321 | T>I | No |
ClinGen Ensembl |
|
| TCGA novel | 324 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821490 rs757227097 |
328 | E>D | No |
ClinGen ExAC gnomAD |
|
|
rs998735488 CA182738444 |
330 | G>R | No |
ClinGen TOPMed |
|
|
rs1487296943 CA371849699 |
335 | Y>F | No |
ClinGen TOPMed |
|
|
rs957469599 CA182738449 |
336 | L>V | No |
ClinGen Ensembl |
|
|
rs1563600145 CA371849726 |
338 | V>L | No |
ClinGen Ensembl |
|
|
CA371849749 rs1586557884 |
340 | I>N | No |
ClinGen Ensembl |
|
|
rs1160438386 CA371849744 |
340 | I>V | No |
ClinGen Ensembl |
|
|
CA4821495 rs751114787 |
342 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs1292166146 CA371849769 |
342 | I>T | No |
ClinGen gnomAD |
|
|
rs1586557896 CA371849782 |
343 | F>S | No |
ClinGen Ensembl |
|
|
CA4821497 rs139025562 |
344 | S>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs769318500 CA4821499 |
345 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA371849818 rs1472287991 |
347 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
COSM1662390 CA371849819 rs1472287991 |
347 | A>T | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA371849824 rs1272046196 |
347 | A>V | No |
ClinGen TOPMed |
|
|
rs746391617 CA4821502 |
350 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA4821503 rs772271323 |
351 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA371849899 rs1398212581 |
354 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs775985081 CA4821504 |
355 | N>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1563600185 CA371849930 |
356 | E>D | No |
ClinGen Ensembl |
|
|
rs769042324 CA4821506 |
356 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA4821507 rs776827428 |
357 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761932638 CA4821508 |
359 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761932638 CA371849955 |
359 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA371849960 rs1357735601 |
359 | A>V | No |
ClinGen TOPMed |
|
|
rs1586557929 CA371849962 |
360 | T>P | No |
ClinGen Ensembl |
|
|
rs963859388 CA182738463 |
362 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA4821510 rs765435145 |
363 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765435145 COSM1319677 CA4821509 |
363 | A>V | Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs976059421 CA182738466 |
364 | C>S | No |
ClinGen Ensembl |
|
|
CA371850048 rs1563600201 |
367 | W>* | No |
ClinGen Ensembl |
|
|
rs751437110 COSM221433 CA4821513 |
370 | V>I | Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA371850118 rs1207181609 |
373 | T>S | No |
ClinGen gnomAD |
|
|
CA371850162 rs371574913 |
377 | Y>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1586557956 CA371850153 |
377 | Y>D | No |
ClinGen Ensembl |
|
| TCGA novel | 377 | Y>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs374343304 CA4821516 CA4821515 |
378 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 379 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA371850177 rs755556276 |
379 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA4821517 rs755556276 |
379 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1187451066 CA371850195 |
381 | V>I | No |
ClinGen gnomAD |
|
|
CA182738481 rs909380784 |
384 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs201873843 CA4821522 |
385 | T>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
COSM2792664 rs201873843 CA4821521 |
385 | T>M | Variant assessed as Somatic; 0.0 impact. oesophagus [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA182738486 rs201873843 |
385 | T>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1294465684 CA371850263 |
388 | K>E | No |
ClinGen TOPMed |
|
|
rs762126871 CA4821525 |
388 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA4821527 rs773398889 |
390 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs1298481405 CA371850291 |
391 | A>T | No |
ClinGen gnomAD |
|
|
CA371850298 rs1367400500 |
391 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs201132040 CA4821530 COSM1211648 |
398 | G>D | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
rs1380809648 CA371850414 |
401 | V>M | No |
ClinGen Ensembl |
|
|
rs1219662408 CA371850438 |
403 | V>I | No |
ClinGen gnomAD |
|
|
CA371850462 rs1280458788 |
405 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs755826314 CA4821534 |
406 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA4821537 rs758811663 |
408 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs753432079 CA4821536 |
408 | L>S | No |
ClinGen ExAC gnomAD |
|
|
CA371850546 rs1335226773 |
411 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1478640524 CA371850595 |
414 | S>F | No |
ClinGen gnomAD |
|
|
rs1385648936 CA371850603 |
415 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1165607979 CA371850625 |
417 | Y>D | No |
ClinGen TOPMed |
|
|
CA4821539 rs149723156 |
418 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4821540 rs755324744 |
418 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA4821538 rs149723156 |
418 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs781697576 COSM455002 CA4821541 |
419 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
COSM1102909 CA371850646 rs1321499528 |
419 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA4821542 rs748367691 |
421 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 421 | K>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821543 rs770119619 |
422 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 422 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs773134157 CA4821544 |
423 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1330511797 CA371850706 |
424 | E>K | No |
ClinGen gnomAD |
|
|
CA371850731 rs1233855483 |
425 | S>T | No |
ClinGen gnomAD |
|
|
CA4821545 rs749432677 |
426 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 427 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4821546 rs770948960 |
428 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA4821547 rs377211918 |
428 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs994439138 CA371850807 |
431 | D>H | No |
ClinGen TOPMed |
|
|
rs994439138 CA182738514 |
431 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs767287793 CA4821549 |
435 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 436 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1262137749 CA371850887 |
437 | K>N | No |
ClinGen gnomAD |
|
|
rs1266034784 CA371850912 |
440 | P>S | No |
ClinGen gnomAD |
|
| TCGA novel | 441 | S>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA371850931 rs1452738924 |
441 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA4821552 rs763859114 |
442 | V>D | No |
ClinGen ExAC gnomAD |
|
|
rs760293863 CA4821551 |
442 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821553 rs753452243 |
443 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA371850991 rs1333005998 |
446 | D>E | No |
ClinGen TOPMed |
|
|
CA371850989 rs1414555600 |
446 | D>V | No |
ClinGen gnomAD |
|
|
CA182738521 rs773696797 |
448 | Y>D | No |
ClinGen Ensembl |
|
|
CA182738525 rs906910272 |
449 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
CA4821555 rs764653918 |
449 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA4821556 rs752051290 |
450 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs1388553228 CA371851024 |
450 | H>Y | No |
ClinGen gnomAD |
|
|
CA4821557 rs755600361 |
451 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821558 rs781686718 |
451 | K>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 452 | V>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 453 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1288743836 CA371851076 |
454 | S>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA4821559 rs748561913 |
455 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA4821561 rs778018003 |
456 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA4821560 rs756265826 |
456 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs1356472651 CA371851117 |
457 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA371851123 rs1211054710 |
458 | S>N | No |
ClinGen gnomAD |
|
|
CA4821562 rs749478032 |
460 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821564 rs774471813 |
462 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA182738536 rs892956498 |
462 | M>T | No |
ClinGen TOPMed |
|
|
CA182738541 rs745804262 |
463 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs745804262 CA4821565 |
463 | S>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 466 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs772041898 CA4821566 |
467 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA371851244 rs1253798929 |
468 | S>N | No |
ClinGen TOPMed |
|
|
rs775246273 CA4821567 |
473 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821568 rs760472450 |
475 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA4821571 rs778272599 |
477 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4821572 rs541495971 |
477 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4821573 rs541495971 |
477 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
No associated diseases with Q9ULS6
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| voltage-gated potassium channel complex | A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| voltage-gated potassium channel activity | Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| potassium ion transmembrane transport | A process in which a potassium ion is transported from one side of a membrane to the other. |
| potassium ion transport | The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| protein homooligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| regulation of delayed rectifier potassium channel activity | Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity. |
22 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q4ZHA6 | KCNB2 | Potassium voltage-gated channel subfamily B member 2 | Bos taurus (Bovine) | PR |
| P17972 | Shaw | Potassium voltage-gated channel protein Shaw | Drosophila melanogaster (Fruit fly) | PR |
| Q14721 | KCNB1 | Potassium voltage-gated channel subfamily B member 1 | Homo sapiens (Human) | PR |
| Q8TDN2 | KCNV2 | Potassium voltage-gated channel subfamily V member 2 | Homo sapiens (Human) | PR |
| Q92953 | KCNB2 | Potassium voltage-gated channel subfamily B member 2 | Homo sapiens (Human) | PR |
| Q9H3M0 | KCNF1 | Potassium voltage-gated channel subfamily F member 1 | Homo sapiens (Human) | PR |
| Q96RP8 | KCNA7 | Potassium voltage-gated channel subfamily A member 7 | Homo sapiens (Human) | PR |
| P22459 | KCNA4 | Potassium voltage-gated channel subfamily A member 4 | Homo sapiens (Human) | PR |
| P22001 | KCNA3 | Potassium voltage-gated channel subfamily A member 3 | Homo sapiens (Human) | PR |
| Q16322 | KCNA10 | Potassium voltage-gated channel subfamily A member 10 | Homo sapiens (Human) | PR |
| Q09470 | KCNA1 | Potassium voltage-gated channel subfamily A member 1 | Homo sapiens (Human) | PR |
| P16389 | KCNA2 | Potassium voltage-gated channel subfamily A member 2 | Homo sapiens (Human) | PR |
| Q9UK17 | KCND3 | Potassium voltage-gated channel subfamily D member 3 | Homo sapiens (Human) | PR |
| Q03721 | KCNC4 | Potassium voltage-gated channel subfamily C member 4 | Homo sapiens (Human) | PR |
| Q80XM3 | Kcng4 | Potassium voltage-gated channel subfamily G member 4 | Mus musculus (Mouse) | PR |
| Q03717 | Kcnb1 | Potassium voltage-gated channel subfamily B member 1 | Mus musculus (Mouse) | PR |
| A6H8H5 | Kcnb2 | Potassium voltage-gated channel subfamily B member 2 | Mus musculus (Mouse) | PR |
| Q7TSH7 | Kcnf1 | Potassium voltage-gated channel subfamily F member 1 | Mus musculus (Mouse) | PR |
| O35174 | Kcns2 | Potassium voltage-gated channel subfamily S member 2 | Mus musculus (Mouse) | PR |
| O18868 | KCNB1 | Potassium voltage-gated channel subfamily B member 1 | Sus scrofa (Pig) | PR |
| P15387 | Kcnb1 | Potassium voltage-gated channel subfamily B member 1 | Rattus norvegicus (Rat) | PR |
| Q9ER26 | Kcns2 | Potassium voltage-gated channel subfamily S member 2 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTGQSLWDVS | EANVEDGEIR | INVGGFKRRL | RSHTLLRFPE | TRLGRLLLCH | SREAILELCD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DYDDVQREFY | FDRNPELFPY | VLHFYHTGKL | HVMAELCVFS | FSQEIEYWGI | NEFFIDSCCS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YSYHGRKVEP | EQEKWDEQSD | QESTTSSFDE | ILAFYNDASK | FDGQPLGNFR | RQLWLALDNP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GYSVLSRVFS | ILSILVVMGS | IITMCLNSLP | DFQIPDSQGN | PGEDPRFEIV | EHFGIAWFTF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELVARFAVAP | DFLKFFKNAL | NLIDLMSIVP | FYITLVVNLV | VESTPTLANL | GRVAQVLRLM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RIFRILKLAR | HSTGLRSLGA | TLKYSYKEVG | LLLLYLSVGI | SIFSVVAYTI | EKEENEGLAT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IPACWWWATV | SMTTVGYGDV | VPGTTAGKLT | ASACILAGIL | VVVLPITLIF | NKFSHFYRRQ |
| 430 | 440 | 450 | 460 | 470 | |
| KQLESAMRSC | DFGDGMKEVP | SVNLRDYYAH | KVKSLMASLT | NMSRSSPSEL | SLNDSLR |