Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SS40

Entry ID Method Resolution Chain Position Source
AF-Q9SS40-F1 Predicted AlphaFoldDB

31 variants for Q9SS40

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH02128255 21 K>Q No 1000Genomes
tmp_3_3185239_G_A 29 S>L No 1000Genomes
ENSVATH05803172 33 M>I No 1000Genomes
ENSVATH05803171 43 D>N No 1000Genomes
ENSVATH10583467 44 M>K No 1000Genomes
ENSVATH02128254 50 S>Y No 1000Genomes
ENSVATH05803169 61 L>* No 1000Genomes
ENSVATH05803168 61 L>F No 1000Genomes
ENSVATH05803170 61 L>I No 1000Genomes
ENSVATH02128253 64 L>P No 1000Genomes
ENSVATH02128252 67 T>S No 1000Genomes
ENSVATH00314937 69 N>D No 1000Genomes
tmp_3_3185068_T_A 86 K>I No 1000Genomes
ENSVATH00314936 89 I>F No 1000Genomes
tmp_3_3185003_C_T 108 V>I No 1000Genomes
ENSVATH05803167 130 L>H No 1000Genomes
ENSVATH10583466 131 S>C No 1000Genomes
tmp_3_3184859_C_T 156 V>I No 1000Genomes
tmp_3_3184775_G_A 184 L>F No 1000Genomes
tmp_3_3184763_C_A 188 V>F No 1000Genomes
tmp_3_3183966_C_A 233 R>M No 1000Genomes
tmp_3_3183950_A_C 238 N>K No 1000Genomes
ENSVATH05803160 245 P>R No 1000Genomes
ENSVATH10583398 249 I>V No 1000Genomes
tmp_3_3183835_A_C 277 Y>D No 1000Genomes
ENSVATH10583397 283 N>S No 1000Genomes
tmp_3_3183810_A_G 285 V>A No 1000Genomes
tmp_3_3183757_C_A 303 A>S No 1000Genomes
tmp_3_3183590_G_A 330 T>M No 1000Genomes
tmp_3_3183554_A_G 342 L>P No 1000Genomes
tmp_3_3183533_T_C 349 E>G No 1000Genomes

No associated diseases with Q9SS40

5 regional properties for Q9SS40

Type Name Position InterPro Accession
domain BTB/POZ domain 203 - 303 IPR000210-1
domain BTB/POZ domain 343 - 455 IPR000210-2
domain Coagulation factor 5/8 C-terminal domain 666 - 793 IPR000421
domain BTB/Kelch-associated 461 - 584 IPR011705
domain Farnesoic acid O-methyl transferase 52 - 151 IPR022041

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).

1 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0CK97 SLC35E2A Solute carrier family 35 member E2A Homo sapiens (Human) PR
Q96K37 SLC35E1 Solute carrier family 35 member E1 Homo sapiens (Human) PR
P0CK96 SLC35E2B Solute carrier family 35 member E2B Homo sapiens (Human) PR
Q8C811 Slc35e2a Solute carrier family 35 member E2A Mus musculus (Mouse) PR
Q8CD26 Slc35e1 Solute carrier family 35 member E1 Mus musculus (Mouse) PR
Q8RXL8 UXT3 UDP-xylose transporter 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRE4 URGT1 UDP-rhamnose/UDP-galactose transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H0T6 PPT2 Phosphoenolpyruvate/phosphate translocator 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSSHARGKEL IPLLSFSHQK KQPNLSISST TKMNKKNPDQ KSDMSSSSSS PKKQTLFISS
70 80 90 100 110 120
LIILWYTSNI GVLLLNKFLL SNYGFKFPIF LTMCHMSACA ILSYVSIVFL KLVPLQYLKS
130 140 150 160 170 180
RSQFLKVATL SIVFCASVVG GNISLRYLPV SFNQAVGATT PFFTALFAYI MTFKREAWVT
190 200 210 220 230 240
YGALVPVVTG VVIASGGEPG FHWFGFIMCI SATAARAFKS VLQGILLSSE GERLNSMNLM
250 260 270 280 290 300
LYMSPIAVIA LLPVTIFMEP DVMSVTLTLG RQHKYMYILL LVNSVMAYSA NLLNFLVTKH
310 320 330 340 350
TSALTLQVLG NAKGAVAVVI SILLFRNPVT VMGIGGYSIT VLGVVAYGET KRRFR