Q8CD26

PR
Gene name
Slc35e1
Protein name
Solute carrier family 35 member E1
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:270066
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

315-396 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8CD26

Entry ID Method Resolution Chain Position Source
AF-Q8CD26-F1 Predicted AlphaFoldDB

13 variants for Q8CD26

Variant ID(s) Position Change Description Diseaes Association Provenance
rs258079223 6 T>A No EVA
rs3399172369 104 P>S No EVA
rs3399172348 138 A>P No EVA
rs213248215 174 S>I No EVA
rs3399256350 211 V>E No EVA
rs3399243863 256 S>T No EVA
rs3398796244 257 Q>G No EVA
rs51818739 324 T>I No EVA
rs3399333717 337 Y>N No EVA
rs3388988400 347 L>F No EVA
rs3388996043 351 S>F No EVA
rs3399076240 376 Q>P No EVA
rs3388991979 404 L>I No EVA

No associated diseases with Q8CD26

1 regional properties for Q8CD26

Type Name Position InterPro Accession
domain Sugar phosphate transporter domain 29 - 333 IPR004853

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0CK97 SLC35E2A Solute carrier family 35 member E2A Homo sapiens (Human) PR
P0CK96 SLC35E2B Solute carrier family 35 member E2B Homo sapiens (Human) PR
Q96K37 SLC35E1 Solute carrier family 35 member E1 Homo sapiens (Human) PR
Q8C811 Slc35e2a Solute carrier family 35 member E2A Mus musculus (Mouse) PR
Q8RXL8 UXT3 UDP-xylose transporter 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRE4 URGT1 UDP-rhamnose/UDP-galactose transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SS40 At3g10290 Probable sugar phosphate/phosphate translocator At3g10290 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H0T6 PPT2 Phosphoenolpyruvate/phosphate translocator 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAAAATAGPG AGAGVPGAGG GGGAREGARV AVLCLLWYAL SAGGNVVNKV ILSAFPFPVT
70 80 90 100 110 120
VSLCHILALC AGLPPLLRAW RVPPAPPVSG PGPGPHPASG PLLPPRFYPR YVLPLAFGKY
130 140 150 160 170 180
FASVSAHVSI WKVPVSYAHT VKATMPIWVV LLSRIIMKEK QSTKVYLSLV PIISGVLLAT
190 200 210 220 230 240
VTELSFDVWG LVSALAATLC FSLQNIFSKK VLRDSRIHHL RLLNILGCHA VFFMIPTWVL
250 260 270 280 290 300
VDLSTFLVSS DLAYVSQWPW TLLLLAVSGF CNFAQNVIAF SILNLISPLS YSVANATKRI
310 320 330 340 350 360
MVITVSLIML RNPVTSTNVL GMMTAILGVF LYNKTKYDAN QQARRHLLPI STSDLSSREH
370 380 390 400
LRSPVEKPHN GALFPQQGDF QYRNILLTDH FQYSRQGHPN SYALSRHDV